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ChEMBL ligand: CHEMBL1254577 |
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DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
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PLD1/Phospholipase D1 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2536] [GtoPdb: 1433] [UniProtKB: Q13393] | ||||||||
ChEMBL | Inhibition of PLD1 in human calu1 cells | B | 5.82 | pIC50 | 1500 | nM | IC50 | J. Med. Chem. (2010) 53: 6706-6719 [PMID:20735042] |
ChEMBL | Inhibition of PLD1 (unknown origin) | B | 5.82 | pIC50 | 1500 | nM | IC50 | Bioorg Med Chem Lett (2018) 28: 3670-3673 [PMID:30528979] |
PLD2/Phospholipase D2 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2734] [GtoPdb: 1434] [UniProtKB: O14939] | ||||||||
ChEMBL | Inhibition of human GST-tagged PLD2A in human HEK293 cells | B | 7.7 | pIC50 | 20 | nM | IC50 | J. Med. Chem. (2010) 53: 6706-6719 [PMID:20735042] |
ChEMBL | Inhibition of PLD2 (unknown origin) | B | 7.7 | pIC50 | 20 | nM | IC50 | Bioorg Med Chem Lett (2018) 28: 3670-3673 [PMID:30528979] |
GtoPdb | - | - | 7.7 | pIC50 | 19.9 | nM | IC50 | J Med Chem (2010) 53: 6706-19 [PMID:20735042] |
ChEMBL data shown on this page come from version 28:
Gaulton A, Hersey A, Nowotka M, Bento AP, Chambers J, Mendez D, Mutowo P, Atkinson F, Bellis LJ, CibriƔn-Uhalte E, Davies M, Dedman N, Karlsson A, MagariƱos MP, Overington JP, Papadatos G, Smit I, Leach AR. (2017) 'The ChEMBL database in 2017.' Nucleic Acids Res., 45(D1). DOI: 10.1093/nar/gkw1074. [PMCID:5210557]