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ChEMBL ligand: CHEMBL36060 (CGP-12177A) |
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DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
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β1-adrenoceptor/Beta-1 adrenergic receptor in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL213] [GtoPdb: 28] [UniProtKB: P08588] | ||||||||
GtoPdb | - | - | 9.2 | pKd | - | - | - |
Naunyn Schmiedebergs Arch Pharmacol (2004) 369: 525-32 [PMID:15060759]; Br J Pharmacol (2005) 144: 317-22 [PMID:15655528] |
GtoPdb | - | - | 9.9 | pKd | - | - | - | Naunyn Schmiedebergs Arch Pharmacol (2004) 369: 525-32 [PMID:15060759] |
ChEMBL | Inhibition of I-iodocyanopindolol binding to human beta 1 adrenergic receptors | B | 9.6 | pKi | 0.25 | nM | Ki | J Med Chem (2001) 44: 1456-1466 [PMID:11311069] |
β2-adrenoceptor/Beta-2 adrenergic receptor in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL210] [GtoPdb: 29] [UniProtKB: P07550] | ||||||||
ChEMBL | Inhibition of I-iodocyanopindolol binding to human beta 2 adrenergic receptors | B | 10 | pKi | 0.1 | nM | Ki | J Med Chem (2001) 44: 1456-1466 [PMID:11311069] |
ChEMBL data shown on this page come from version 32:
Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]