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ChEMBL ligand: CHEMBL36060 (CGP-12177A) |
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DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
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β1-adrenoceptor/Beta-1 adrenergic receptor in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL213] [GtoPdb: 28] [UniProtKB: P08588] | ||||||||
GtoPdb | - | - | 9.2 | pKd | - | - | - |
Naunyn Schmiedebergs Arch Pharmacol (2004) 369: 525-32 [PMID:15060759]; Br J Pharmacol (2005) 144: 317-22 [PMID:15655528] |
GtoPdb | - | - | 9.9 | pKd | - | - | - | Naunyn Schmiedebergs Arch Pharmacol (2004) 369: 525-32 [PMID:15060759] |
ChEMBL | Inhibition of I-iodocyanopindolol binding to human beta 1 adrenergic receptors | B | 9.6 | pKi | 0.25 | nM | Ki | J. Med. Chem. (2001) 44: 1456-1466 [PMID:11311069] |
β2-adrenoceptor/Beta-2 adrenergic receptor in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL210] [GtoPdb: 29] [UniProtKB: P07550] | ||||||||
ChEMBL | Inhibition of I-iodocyanopindolol binding to human beta 2 adrenergic receptors | B | 10 | pKi | 0.1 | nM | Ki | J. Med. Chem. (2001) 44: 1456-1466 [PMID:11311069] |
ChEMBL data shown on this page come from version 31:
Gaulton A, Hersey A, Nowotka M, Bento AP, Chambers J, Mendez D, Mutowo P, Atkinson F, Bellis LJ, CibriƔn-Uhalte E, Davies M, Dedman N, Karlsson A, MagariƱos MP, Overington JP, Papadatos G, Smit I, Leach AR. (2017) 'The ChEMBL database in 2017.' Nucleic Acids Res., 45(D1). DOI: 10.1093/nar/gkw1074. [PMCID:5210557]