[3H]azietomidate [Ligand Id: 5404] activity data from GtoPdb and ChEMBL

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ChEMBL ligand: CHEMBL23812
  • nicotinic acetylcholine receptor δ subunit/nicotinic acetylcholine receptor α1 subunit/nicotinic acetylcholine receptor γ subunit/nicotinic acetylcholine receptor β1 subunit/Nicotinic acetylcholine receptor alpha1/beta1/gamma/delta in Mouse [ChEMBL: CHEMBL3038460] [GtoPdb: 476, 462, 475, 471] [UniProtKB: P02716, P04756, P04760, P09690]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
nicotinic acetylcholine receptor δ subunit/nicotinic acetylcholine receptor α1 subunit/nicotinic acetylcholine receptor γ subunit/nicotinic acetylcholine receptor β1 subunit/Nicotinic acetylcholine receptor alpha1/beta1/gamma/delta in Mouse (target type: PROTEIN COMPLEX) [ChEMBL: CHEMBL3038460] [GtoPdb: 476, 462, 475, 471] [UniProtKB: P02716, P04756, P04760, P09690]
ChEMBL Inhibition of recombinant embryonic mouse muscle Nicotinic Acetylcholine Receptor (3 oocytes) B 4.6 pIC50 25000 nM IC50 J Med Chem (2003) 46: 1257-1265 [PMID:12646036]

ChEMBL data shown on this page come from version 32:

Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]