[3H]azietomidate [Ligand Id: 5404] activity data from GtoPdb and ChEMBL

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ChEMBL ligand: CHEMBL23812
  • nicotinic acetylcholine receptor δ subunit/nicotinic acetylcholine receptor α1 subunit/nicotinic acetylcholine receptor γ subunit/nicotinic acetylcholine receptor β1 subunit/Nicotinic acetylcholine receptor alpha1/beta1/gamma/delta in Mouse [ChEMBL: CHEMBL3038460] [GtoPdb: 476, 462, 475, 471] [UniProtKB: P02716, P04756, P04760, P09690]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
nicotinic acetylcholine receptor δ subunit/nicotinic acetylcholine receptor α1 subunit/nicotinic acetylcholine receptor γ subunit/nicotinic acetylcholine receptor β1 subunit/Nicotinic acetylcholine receptor alpha1/beta1/gamma/delta in Mouse (target type: PROTEIN COMPLEX) [ChEMBL: CHEMBL3038460] [GtoPdb: 476, 462, 475, 471] [UniProtKB: P02716, P04756, P04760, P09690]
ChEMBL Inhibition of recombinant embryonic mouse muscle Nicotinic Acetylcholine Receptor (3 oocytes) B 4.6 pIC50 25000 nM IC50 J. Med. Chem. (2003) 46: 1257-1265 [PMID:12646036]

ChEMBL data shown on this page come from version 31:

Gaulton A, Hersey A, Nowotka M, Bento AP, Chambers J, Mendez D, Mutowo P, Atkinson F, Bellis LJ, Cibrián-Uhalte E, Davies M, Dedman N, Karlsson A, Magariños MP, Overington JP, Papadatos G, Smit I, Leach AR. (2017) 'The ChEMBL database in 2017.' Nucleic Acids Res., 45(D1). DOI: 10.1093/nar/gkw1074. [PMCID:5210557]