AC45594 [Ligand Id: 5422] activity data from GtoPdb and ChEMBL

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ChEMBL ligand: CHEMBL193558 (A-45594)
  • Androgen receptor/Androgen Receptor in Rat [ChEMBL: CHEMBL3072] [GtoPdb: 628] [UniProtKB: P15207]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
Androgen receptor/Androgen Receptor in Rat (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3072] [GtoPdb: 628] [UniProtKB: P15207]
ChEMBL Inhibitory concentration against recombinant rat androgen receptor expressed in Escherichia coli using [3H]methyltrienolone (R 1881) B 4.83 pIC50 14791.08 nM IC50 J. Med. Chem. (2005) 48: 5666-5674 [PMID:16134935]
Steroidogenic factor 1 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL4666] [GtoPdb: 632] [UniProtKB: Q13285]
ChEMBL Inverse agonist activity at SF-1 F 5.14 pIC50 7300 nM IC50 J. Med. Chem. (2011) 54: 2266-2281 [PMID:21391689]

ChEMBL data shown on this page come from version 31:

Gaulton A, Hersey A, Nowotka M, Bento AP, Chambers J, Mendez D, Mutowo P, Atkinson F, Bellis LJ, Cibrián-Uhalte E, Davies M, Dedman N, Karlsson A, Magariños MP, Overington JP, Papadatos G, Smit I, Leach AR. (2017) 'The ChEMBL database in 2017.' Nucleic Acids Res., 45(D1). DOI: 10.1093/nar/gkw1074. [PMCID:5210557]