MRS5151 [Ligand Id: 5622] activity data from GtoPdb

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  • A1 receptor in Human [GtoPdb: 18] [UniProtKB: P30542]
  • A1 receptor in Mouse [GtoPdb: 18] [UniProtKB: Q60612]
1 _lig_chart_1 A1 receptor HumanMouse
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  • A2A receptor in Human [GtoPdb: 19] [UniProtKB: P29274]
  • A2A receptor in Mouse [GtoPdb: 19] [UniProtKB: Q60613]
2 _lig_chart_2 A2A receptor HumanMouse
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  • A3 receptor in Human [GtoPdb: 21] [UniProtKB: P0DMS8]
  • A3 receptor in Mouse [GtoPdb: 21] [UniProtKB: Q61618]
3 _lig_chart_3 A3 receptor HumanMouse
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
A1 receptor in Human [GtoPdb: 18] [UniProtKB: P30542]
GtoPdb - - 4.83 pKi 14900 nM Ki Bioorg. Med. Chem. Lett. (2008) 18: 2813-9 [PMID:18424135]
A1 receptor in Mouse [GtoPdb: 18] [UniProtKB: Q60612]
GtoPdb - - 4.98 pKi 10500 nM Ki Bioorg. Med. Chem. Lett. (2008) 18: 2813-9 [PMID:18424135]
A2A receptor in Human [GtoPdb: 19] [UniProtKB: P29274]
GtoPdb - - 5 pKi >10000 nM Ki Bioorg. Med. Chem. Lett. (2008) 18: 2813-9 [PMID:18424135]
A2A receptor in Mouse [GtoPdb: 19] [UniProtKB: Q60613]
GtoPdb - - 5 pKi >10000 nM Ki Bioorg. Med. Chem. Lett. (2008) 18: 2813-9 [PMID:18424135]
A3 receptor in Human [GtoPdb: 21] [UniProtKB: P0DMS8]
GtoPdb - - 8.62 pKi 2.38 nM Ki Bioorg. Med. Chem. Lett. (2008) 18: 2813-9 [PMID:18424135]
A3 receptor in Mouse [GtoPdb: 21] [UniProtKB: Q61618]
GtoPdb - - 7.61 pKi 24.4 nM Ki Bioorg. Med. Chem. Lett. (2008) 18: 2813-9 [PMID:18424135]

Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.