Zn2+ [Ligand Id: 566] activity data from GtoPdb

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  • β2-adrenoceptor in Human [GtoPdb: 29] [UniProtKB: P07550]
  • 4.3
1 _lig_chart_1 β2-adrenoceptor Human
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  • GPR83 in Mouse [GtoPdb: 119] [UniProtKB: P30731]
  • This target only has 0 pki data point
  • 0
2 _lig_chart_2 GPR83 Mouse
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  • glycine receptor α1 subunit in Human [GtoPdb: 423] [UniProtKB: P23415]
  • This target only has 0 pki data point
  • 0
3 _lig_chart_3 glycine receptor α1 subunit Human
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  • glycine receptor α2 subunit in Human [GtoPdb: 424] [UniProtKB: P23416]
  • This target only has 0 pki data point
  • 0
4 _lig_chart_4 glycine receptor α2 subunit Human
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  • glycine receptor α3 subunit in Human [GtoPdb: 425] [UniProtKB: O75311]
  • This target only has 0 pki data point
  • 0
5 _lig_chart_5 glycine receptor α3 subunit Human
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  • glycine receptor β subunit in Human [GtoPdb: 427] [UniProtKB: P48167]
  • This target only has 0 pki data point
  • 0
6 _lig_chart_6 glycine receptor β subunit Human
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  • TRPA1 in Mouse [GtoPdb: 485] [UniProtKB: Q8BLA8]
  • This target only has 0 pki data point
  • 0
7 _lig_chart_7 TRPA1 Mouse
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  • TRPM1 in Human [GtoPdb: 493] [UniProtKB: Q7Z4N2]
  • This target only has 0 pki data point
  • 0
8 _lig_chart_8 TRPM1 Human
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  • TRPM2 in Human [GtoPdb: 494] [UniProtKB: O94759]
  • This target only has 0 pki data point
  • 0
9 _lig_chart_9 TRPM2 Human
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  • ZAC in Human [GtoPdb: 587] [UniProtKB: Q401N2]
  • This target only has 0 pki data point
  • 0
10 _lig_chart_10 ZAC Human
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  • ASIC1 in Human [GtoPdb: 684] [UniProtKB: P78348]
  • This target only has 0 pki data point
  • 0
11 _lig_chart_11 ASIC1 Human
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  • ASIC3 in Human [GtoPdb: 686] [UniProtKB: Q9UHC3]
  • This target only has 0 pki data point
  • 0
12 _lig_chart_12 ASIC3 Human
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  • ClC-4 in Human [GtoPdb: 703] [UniProtKB: P51793]
  • This target only has 0 pki data point
  • 0
13 _lig_chart_13 ClC-4 Human
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  • Maxi Cl- in Human [GtoPdb: 709]
  • This target only has 0 pki data point
  • 0
14 _lig_chart_14 Maxi Cl- Human
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  • Hv1 in Human [GtoPdb: 746] [UniProtKB: Q96D96]
  • This target only has 0 pki data point
  • 0
15 _lig_chart_15 Hv1 Human
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
β2-adrenoceptor in Human [GtoPdb: 29] [UniProtKB: P07550]
GtoPdb - - 3.3 pKi - - - J Biol Chem (2003) 278: 352-6 [PMID:12409304];
Mol Pharmacol (2002) 61: 65-72 [PMID:11752207]
GtoPdb - - 5.3 pKi - - - J Biol Chem (2003) 278: 352-6 [PMID:12409304];
Mol Pharmacol (2002) 61: 65-72 [PMID:11752207]
GPR83 in Mouse [GtoPdb: 119] [UniProtKB: P30731]
GtoPdb - - 5 pEC50 10200 nM EC50 PLoS ONE (2013) 8: e53347 [PMID:23335960]
glycine receptor α1 subunit in Human [GtoPdb: 423] [UniProtKB: P23415]
GtoPdb - - 4.8 pIC50 15000 nM IC50
GtoPdb - - 7.4 pEC50 37 nM EC50
glycine receptor α2 subunit in Human [GtoPdb: 424] [UniProtKB: P23416]
GtoPdb - - 3.4 pIC50 360000 nM IC50
GtoPdb - - 6.3 pEC50 540 nM EC50
glycine receptor α3 subunit in Human [GtoPdb: 425] [UniProtKB: O75311]
GtoPdb - - 3.8 pIC50 150000 nM IC50
glycine receptor β subunit in Human [GtoPdb: 427] [UniProtKB: P48167]
GtoPdb - - 3.7 pIC50 180000 nM IC50
GtoPdb - - 4.9 pIC50 13000 nM IC50
TRPA1 in Mouse [GtoPdb: 485] [UniProtKB: Q8BLA8]
GtoPdb Calcium imaging - 2.3 pEC50 - - - Nat Chem Biol (2009) 5: 183-90 [PMID:19202543];
Proc Natl Acad Sci USA (2009) 106: 8374-9 [PMID:19416844]
TRPM1 in Human [GtoPdb: 493] [UniProtKB: Q7Z4N2]
GtoPdb - - 6 pIC50 1000 nM IC50
TRPM2 in Human [GtoPdb: 494] [UniProtKB: O94759]
GtoPdb - - 6 pIC50 1000 nM IC50
ZAC in Human [GtoPdb: 587] [UniProtKB: Q401N2]
GtoPdb - - 3.7 pEC50 - - EC50 J Biol Chem (2003) 278: 712-7 [PMID:12381728];
Biochem Pharmacol (2016) 103: 109-17 [PMID:26872532]
ASIC1 in Human [GtoPdb: 684] [UniProtKB: P78348]
GtoPdb - - 8.2 pIC50 ~7 nM IC50 J Neurosci (2004) 24: 8678-89 [PMID:15470133]
ASIC3 in Human [GtoPdb: 686] [UniProtKB: Q9UHC3]
GtoPdb - - 4.2 pIC50 61000 nM IC50 Neuroscience (2010) 169: 574-83 [PMID:20580786]
ClC-4 in Human [GtoPdb: 703] [UniProtKB: P51793]
GtoPdb - - 4.3 pIC50 50000 nM IC50 Biophys J (2008) 95: 4668-75 [PMID:18658230]
Maxi Cl- in Human [GtoPdb: 709]
GtoPdb - - 4.3 pIC50 50000 nM IC50 Biophys J (2008) 95: 4668-75 [PMID:18658230]
Hv1 in Human [GtoPdb: 746] [UniProtKB: Q96D96]
GtoPdb - - 6.3 pIC50 ~500 nM IC50

Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.