Zn2+ [Ligand Id: 566] activity data from GtoPdb

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  • β2-adrenoceptor in Human [GtoPdb: 29] [UniProtKB: P07550]
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  • GPR83 in Mouse [GtoPdb: 119] [UniProtKB: P30731]
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  • glycine receptor α1 subunit in Human [GtoPdb: 423] [UniProtKB: P23415]
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  • glycine receptor α2 subunit in Human [GtoPdb: 424] [UniProtKB: P23416]
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  • glycine receptor α3 subunit in Human [GtoPdb: 425] [UniProtKB: O75311]
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  • glycine receptor β subunit in Human [GtoPdb: 427] [UniProtKB: P48167]
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  • TRPA1 in Mouse [GtoPdb: 485] [UniProtKB: Q8BLA8]
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  • TRPM1 in Human [GtoPdb: 493] [UniProtKB: Q7Z4N2]
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  • TRPM2 in Human [GtoPdb: 494] [UniProtKB: O94759]
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  • ZAC in Human [GtoPdb: 587] [UniProtKB: Q401N2]
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  • ASIC1 in Human [GtoPdb: 684] [UniProtKB: P78348]
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  • ASIC3 in Human [GtoPdb: 686] [UniProtKB: Q9UHC3]
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  • ClC-4 in Human [GtoPdb: 703] [UniProtKB: P51793]
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  • Maxi Cl- in Human [GtoPdb: 709]
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  • Hv1 in Human [GtoPdb: 746] [UniProtKB: Q96D96]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
β2-adrenoceptor in Human [GtoPdb: 29] [UniProtKB: P07550]
GtoPdb - - 3.3 pKi - - - J. Biol. Chem. (2003) 278: 352-6 [PMID:12409304];
Mol. Pharmacol. (2002) 61: 65-72 [PMID:11752207]
GtoPdb - - 5.3 pKi - - - J. Biol. Chem. (2003) 278: 352-6 [PMID:12409304];
Mol. Pharmacol. (2002) 61: 65-72 [PMID:11752207]
GPR83 in Mouse [GtoPdb: 119] [UniProtKB: P30731]
GtoPdb - - 5 pEC50 10200 nM EC50 PLoS ONE (2013) 8: e53347 [PMID:23335960]
glycine receptor α1 subunit in Human [GtoPdb: 423] [UniProtKB: P23415]
GtoPdb - - 4.8 pIC50 15000 nM IC50
GtoPdb - - 7.4 pEC50 37 nM EC50
glycine receptor α2 subunit in Human [GtoPdb: 424] [UniProtKB: P23416]
GtoPdb - - 3.4 pIC50 360000 nM IC50
GtoPdb - - 6.3 pEC50 540 nM EC50
glycine receptor α3 subunit in Human [GtoPdb: 425] [UniProtKB: O75311]
GtoPdb - - 3.8 pIC50 150000 nM IC50
glycine receptor β subunit in Human [GtoPdb: 427] [UniProtKB: P48167]
GtoPdb - - 3.7 pIC50 180000 nM IC50
GtoPdb - - 4.9 pIC50 13000 nM IC50
TRPA1 in Mouse [GtoPdb: 485] [UniProtKB: Q8BLA8]
GtoPdb Calcium imaging - 2.3 pEC50 - - - Nat. Chem. Biol. (2009) 5: 183-90 [PMID:19202543];
Proc. Natl. Acad. Sci. U.S.A. (2009) 106: 8374-9 [PMID:19416844]
TRPM1 in Human [GtoPdb: 493] [UniProtKB: Q7Z4N2]
GtoPdb - - 6 pIC50 1000 nM IC50
TRPM2 in Human [GtoPdb: 494] [UniProtKB: O94759]
GtoPdb - - 6 pIC50 1000 nM IC50
ZAC in Human [GtoPdb: 587] [UniProtKB: Q401N2]
GtoPdb - - 3.7 pEC50 - - EC50 J. Biol. Chem. (2003) 278: 712-7 [PMID:12381728];
Biochem. Pharmacol. (2016) 103: 109-17 [PMID:26872532]
ASIC1 in Human [GtoPdb: 684] [UniProtKB: P78348]
GtoPdb - - 8.2 pIC50 ~7 nM IC50
ASIC3 in Human [GtoPdb: 686] [UniProtKB: Q9UHC3]
GtoPdb - - 4.2 pIC50 61000 nM IC50
ClC-4 in Human [GtoPdb: 703] [UniProtKB: P51793]
GtoPdb - - 4.3 pIC50 50000 nM IC50 Biophys. J. (2008) 95: 4668-75 [PMID:18658230]
Maxi Cl- in Human [GtoPdb: 709]
GtoPdb - - 4.3 pIC50 50000 nM IC50 Biophys. J. (2008) 95: 4668-75 [PMID:18658230]
Hv1 in Human [GtoPdb: 746] [UniProtKB: Q96D96]
GtoPdb - - 6.3 pIC50 ~500 nM IC50

Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.