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1
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β2-adrenoceptor
Human
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2
_lig_chart_2
GPR83
Mouse
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7
_lig_chart_7
TRPA1
Mouse
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8
_lig_chart_8
TRPM1
Human
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9
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TRPM2
Human
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10
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ZAC
Human
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11
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ASIC1
Human
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12
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ASIC3
Human
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13
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ClC-4
Human
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15
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Hv1
Human
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DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
---|---|---|---|---|---|---|---|---|
β2-adrenoceptor in Human [GtoPdb: 29] [UniProtKB: P07550] | ||||||||
GtoPdb | - | - | 3.3 | pKi | - | - | - |
J Biol Chem (2003) 278: 352-6 [PMID:12409304]; Mol Pharmacol (2002) 61: 65-72 [PMID:11752207] |
GtoPdb | - | - | 5.3 | pKi | - | - | - |
J Biol Chem (2003) 278: 352-6 [PMID:12409304]; Mol Pharmacol (2002) 61: 65-72 [PMID:11752207] |
GPR83 in Mouse [GtoPdb: 119] [UniProtKB: P30731] | ||||||||
GtoPdb | - | - | 5 | pEC50 | 10200 | nM | EC50 | PLoS ONE (2013) 8: e53347 [PMID:23335960] |
glycine receptor α1 subunit in Human [GtoPdb: 423] [UniProtKB: P23415] | ||||||||
GtoPdb | - | - | 4.8 | pIC50 | 15000 | nM | IC50 | |
GtoPdb | - | - | 7.4 | pEC50 | 37 | nM | EC50 | |
glycine receptor α2 subunit in Human [GtoPdb: 424] [UniProtKB: P23416] | ||||||||
GtoPdb | - | - | 3.4 | pIC50 | 360000 | nM | IC50 | |
GtoPdb | - | - | 6.3 | pEC50 | 540 | nM | EC50 | |
glycine receptor α3 subunit in Human [GtoPdb: 425] [UniProtKB: O75311] | ||||||||
GtoPdb | - | - | 3.8 | pIC50 | 150000 | nM | IC50 | |
glycine receptor β subunit in Human [GtoPdb: 427] [UniProtKB: P48167] | ||||||||
GtoPdb | - | - | 3.7 | pIC50 | 180000 | nM | IC50 | |
GtoPdb | - | - | 4.9 | pIC50 | 13000 | nM | IC50 | |
TRPA1 in Mouse [GtoPdb: 485] [UniProtKB: Q8BLA8] | ||||||||
GtoPdb | Calcium imaging | - | 2.3 | pEC50 | - | - | - |
Nat Chem Biol (2009) 5: 183-90 [PMID:19202543]; Proc Natl Acad Sci USA (2009) 106: 8374-9 [PMID:19416844] |
TRPM1 in Human [GtoPdb: 493] [UniProtKB: Q7Z4N2] | ||||||||
GtoPdb | - | - | 6 | pIC50 | 1000 | nM | IC50 | |
TRPM2 in Human [GtoPdb: 494] [UniProtKB: O94759] | ||||||||
GtoPdb | - | - | 6 | pIC50 | 1000 | nM | IC50 | |
ZAC in Human [GtoPdb: 587] [UniProtKB: Q401N2] | ||||||||
GtoPdb | - | - | 3.7 | pEC50 | - | - | EC50 |
J Biol Chem (2003) 278: 712-7 [PMID:12381728]; Biochem Pharmacol (2016) 103: 109-17 [PMID:26872532] |
ASIC1 in Human [GtoPdb: 684] [UniProtKB: P78348] | ||||||||
GtoPdb | - | - | 8.2 | pIC50 | ~7 | nM | IC50 | J Neurosci (2004) 24: 8678-89 [PMID:15470133] |
ASIC3 in Human [GtoPdb: 686] [UniProtKB: Q9UHC3] | ||||||||
GtoPdb | - | - | 4.2 | pIC50 | 61000 | nM | IC50 | Neuroscience (2010) 169: 574-83 [PMID:20580786] |
ClC-4 in Human [GtoPdb: 703] [UniProtKB: P51793] | ||||||||
GtoPdb | - | - | 4.3 | pIC50 | 50000 | nM | IC50 | Biophys J (2008) 95: 4668-75 [PMID:18658230] |
Maxi Cl- in Human [GtoPdb: 709] | ||||||||
GtoPdb | - | - | 4.3 | pIC50 | 50000 | nM | IC50 | Biophys J (2008) 95: 4668-75 [PMID:18658230] |
Hv1 in Human [GtoPdb: 746] [UniProtKB: Q96D96] | ||||||||
GtoPdb | - | - | 6.3 | pIC50 | ~500 | nM | IC50 |
Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.