tandutinib [Ligand Id: 5695] activity data from GtoPdb

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  • platelet derived growth factor receptor beta in Human [GtoPdb: 1804] [UniProtKB: P09619]
  • This target only has 0 pki data point
  • 0
1 _lig_chart_1 platelet derived growth factor receptor beta Human
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  • KIT proto-oncogene, receptor tyrosine kinase in Human [GtoPdb: 1805] [UniProtKB: P10721]
  • This target only has 0 pki data point
  • 0
2 _lig_chart_2 KIT proto-oncogene, receptor tyrosine kinase Human
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  • colony stimulating factor 1 receptor in Human [GtoPdb: 1806] [UniProtKB: P07333]
  • This target only has 0 pki data point
  • 0
3 _lig_chart_3 colony stimulating factor 1 receptor Human
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  • fms related receptor tyrosine kinase 3 in Human [GtoPdb: 1807] [UniProtKB: P36888]
  • This target only has 0 pki data point
  • 0
4 _lig_chart_4 fms related receptor tyrosine kinase 3 Human
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
platelet derived growth factor receptor beta in Human [GtoPdb: 1804] [UniProtKB: P09619]
GtoPdb - - 6.7 pIC50 200 nM IC50 Cancer Cell (2002) 1: 421-32 [PMID:12124172]
KIT proto-oncogene, receptor tyrosine kinase in Human [GtoPdb: 1805] [UniProtKB: P10721]
GtoPdb - - 6.77 pIC50 170 nM IC50 Cancer Cell (2002) 1: 421-32 [PMID:12124172]
colony stimulating factor 1 receptor in Human [GtoPdb: 1806] [UniProtKB: P07333]
GtoPdb - - 5.46 pIC50 3430 nM IC50 Cancer Cell (2002) 1: 421-32 [PMID:12124172]
fms related receptor tyrosine kinase 3 in Human [GtoPdb: 1807] [UniProtKB: P36888]
GtoPdb - - 8.52 pKd 3 nM Kd Nat Biotechnol (2011) 29: 1046-51 [PMID:22037378]
GtoPdb - - 6.66 pIC50 220 nM IC50 Cancer Cell (2002) 1: 421-32 [PMID:12124172]

Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.