compound 9n [PMID: 18752940] [Ligand Id: 5795] activity data from GtoPdb and ChEMBL

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ChEMBL ligand: CHEMBL490599
  • HCA2 receptor/Hydroxycarboxylic acid receptor 2 in Human [ChEMBL: CHEMBL3785] [GtoPdb: 312] [UniProtKB: Q8TDS4]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
HCA2 receptor/Hydroxycarboxylic acid receptor 2 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3785] [GtoPdb: 312] [UniProtKB: Q8TDS4]
ChEMBL Displacement of [3H]nicotinic acid from human GPR109A receptor expressed in CHO cells B 6.77 pIC50 170 nM IC50 Bioorg. Med. Chem. Lett. (2008) 18: 4948-4951 [PMID:18752940]
GtoPdb - - 6.77 pEC50 170 nM EC50 Bioorg. Med. Chem. Lett. (2008) 18: 4948-51 [PMID:18752940]
ChEMBL Agonist activity at human GPR109A receptor expressed in CHO cells by [35S]GTPgammaS binding assay F 6.92 pEC50 120 nM EC50 Bioorg. Med. Chem. Lett. (2008) 18: 4948-4951 [PMID:18752940]

ChEMBL data shown on this page come from version 26:

Gaulton A, Hersey A, Nowotka M, Bento AP, Chambers J, Mendez D, Mutowo P, Atkinson F, Bellis LJ, CibriƔn-Uhalte E, Davies M, Dedman N, Karlsson A, MagariƱos MP, Overington JP, Papadatos G, Smit I, Leach AR. (2017) 'The ChEMBL database in 2017.' Nucleic Acids Res., 45(D1). DOI: 10.1093/nar/gkw1074. [PMCID:5210557]