compound 56 [PMID: 8568816] [Ligand Id: 5956] activity data from GtoPdb and ChEMBL

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ChEMBL ligand: CHEMBL35820
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  • epidermal growth factor receptor in Human [GtoPdb: 1797] [UniProtKB: P00533]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
Fructose-1,6-bisphosphatase in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3975] [UniProtKB: P09467]
ChEMBL Concentration required to inhibit the human liver recombinant fructose-1,6-bisphosphatase. B 5.77 pIC50 1700 nM IC50 Bioorg. Med. Chem. Lett. (2001) 11: 17-21 [PMID:11140724]
Fructose-1,6-bisphosphatase in Pig (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2263] [UniProtKB: P00636]
ChEMBL Compound was evaluated for its concentration required to inhibit the porcine kidney F16BPase B 5 pIC50 >10000 nM IC50 Bioorg. Med. Chem. Lett. (2001) 11: 17-21 [PMID:11140724]
Fructose-1,6-bisphosphatase in Rat (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL4391] [UniProtKB: P19112]
ChEMBL Compound was evaluated for its concentration required to inhibit the rat liver F16BPase B 5 pIC50 >10000 nM IC50 Bioorg. Med. Chem. Lett. (2001) 11: 17-21 [PMID:11140724]
epidermal growth factor receptor in Human [GtoPdb: 1797] [UniProtKB: P00533]
GtoPdb - - 11.22 pIC50 0.01 nM IC50 J. Med. Chem. (1996) 39: 267-76 [PMID:8568816]

ChEMBL data shown on this page come from version 27:

Gaulton A, Hersey A, Nowotka M, Bento AP, Chambers J, Mendez D, Mutowo P, Atkinson F, Bellis LJ, CibriƔn-Uhalte E, Davies M, Dedman N, Karlsson A, MagariƱos MP, Overington JP, Papadatos G, Smit I, Leach AR. (2017) 'The ChEMBL database in 2017.' Nucleic Acids Res., 45(D1). DOI: 10.1093/nar/gkw1074. [PMCID:5210557]