galanin(1-16) (rat/mouse/pig) [Ligand Id: 6087] activity data from GtoPdb

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  • GAL1 receptor in Human [GtoPdb: 243] [UniProtKB: P47211]
  • GAL1 receptor in Mouse [GtoPdb: 243] [UniProtKB: P56479]
  • GAL1 receptor in Rat [GtoPdb: 243] [UniProtKB: Q62805]
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  • GAL2 receptor in Human [GtoPdb: 244] [UniProtKB: O43603]
  • GAL2 receptor in Mouse [GtoPdb: 244] [UniProtKB: O88854]
  • GAL2 receptor in Rat [GtoPdb: 244] [UniProtKB: O08726]
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  • GAL3 receptor in Human [GtoPdb: 245] [UniProtKB: O60755]
  • GAL3 receptor in Rat [GtoPdb: 245] [UniProtKB: O88626]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
GAL1 receptor in Human [GtoPdb: 243] [UniProtKB: P47211]
GtoPdb - - 9.3 pKi 0.5 nM Ki J Pharmacol Exp Ther (1998) 287: 448-56 [PMID:9808667];
Peptides (1998) 19: 1771-81 [PMID:9880084];
Proc Natl Acad Sci USA (1994) 91: 9780-3 [PMID:7524088];
J Med Chem (2008) 51: 8038-47 [PMID:19053761]
GtoPdb - - 9.22 pIC50 0.6 nM IC50 Biochem Biophys Res Commun (1997) 233: 823-8 [PMID:9168941];
Brain Res Mol Brain Res (1998) 58: 156-69 [PMID:9685625]
GAL1 receptor in Mouse [GtoPdb: 243] [UniProtKB: P56479]
GtoPdb - - 8.99 pKi 1.02 nM Ki FEBS Lett (1997) 411: 225-30 [PMID:9271210];
J Neurochem (1998) 71: 2252-9 [PMID:9832122]
GAL1 receptor in Rat [GtoPdb: 243] [UniProtKB: Q62805]
GtoPdb - - 9.02 pKi 0.95 nM Ki J Mol Neurosci (1995) 6: 33-41 [PMID:8562318];
Brain Res Mol Brain Res (1995) 34: 179-89 [PMID:8750821];
J Biol Chem (1997) 272: 24612-6 [PMID:9305929];
J Biol Chem (1998) 273: 23321-6 [PMID:9722565];
FEBS Lett (1998) 434: 277-82 [PMID:9742938];
Mol Pharmacol (1997) 52: 337-43 [PMID:9281594];
J Biol Chem (1997) 272: 31949-52 [PMID:9405385]
GtoPdb - - 9.57 pIC50 0.27 nM IC50 Biochem Biophys Res Commun (1997) 233: 823-8 [PMID:9168941];
FEBS Lett (1997) 405: 285-90 [PMID:9108306]
GAL2 receptor in Human [GtoPdb: 244] [UniProtKB: O43603]
GtoPdb - - 8.8 pKi 1.6 nM Ki Peptides (1998) 19: 1771-81 [PMID:9880084];
J Med Chem (2008) 51: 8038-47 [PMID:19053761];
Biochem Biophys Res Commun (1998) 243: 474-9 [PMID:9480833]
GtoPdb - - 8.66 pIC50 2.17 nM IC50 Brain Res Mol Brain Res (1998) 58: 156-69 [PMID:9685625]
GtoPdb - - 9.38 pEC50 0.42 nM EC50 Peptides (1998) 19: 1771-81 [PMID:9880084];
Brain Res Mol Brain Res (1998) 58: 156-69 [PMID:9685625]
GAL2 receptor in Mouse [GtoPdb: 244] [UniProtKB: O88854]
GtoPdb - - 7.93 pKi 11.8 nM Ki J Neurochem (1998) 71: 2252-9 [PMID:9832122]
GAL2 receptor in Rat [GtoPdb: 244] [UniProtKB: O08726]
GtoPdb - - 8.74 pKi 1.8 nM Ki J Biol Chem (1997) 272: 24612-6 [PMID:9305929];
J Biol Chem (1998) 273: 23321-6 [PMID:9722565];
Mol Pharmacol (1997) 52: 337-43 [PMID:9281594];
J Biol Chem (1997) 272: 31949-52 [PMID:9405385];
FEBS Lett (1998) 434: 277-82 [PMID:9742938];
J Neurochem (1998) 71: 2252-9 [PMID:9832122]
GtoPdb - - 8.52 pIC50 3 nM IC50 Brain Res Mol Brain Res (1997) 51: 49-59 [PMID:9427506];
FEBS Lett (1997) 405: 285-90 [PMID:9108306]
GtoPdb - - 7.03 pEC50 94 nM EC50 J Biol Chem (1997) 272: 24612-6 [PMID:9305929]
GAL3 receptor in Human [GtoPdb: 245] [UniProtKB: O60755]
GtoPdb - - 6.5 pKi 316.23 nM Ki J Biol Chem (1998) 273: 23321-6 [PMID:9722565];
Peptides (1998) 19: 1771-81 [PMID:9880084]
GAL3 receptor in Rat [GtoPdb: 245] [UniProtKB: O88626]
GtoPdb - - 7.3 pKi 49.6 nM Ki J Biol Chem (1998) 273: 23321-6 [PMID:9722565];
J Biol Chem (1997) 272: 31949-52 [PMID:9405385];
FEBS Lett (1998) 434: 277-82 [PMID:9742938]

Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.