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ChEMBL ligand: CHEMBL1187471 (Galmic) |
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DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
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GAL1 receptor/Galanin receptor 1 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL4894] [GtoPdb: 243] [UniProtKB: P47211] | ||||||||
ChEMBL | Binding affinity to human GalR1 | B | 4.47 | pKi | 34200 | nM | Ki | J Med Chem (2010) 53: 1871-1875 [PMID:20121116] |
GtoPdb | - | - | 4.47 | pKi | 34200 | nM | Ki |
Neuropeptides (2005) 39: 161-3 [PMID:15944006]; Proc Natl Acad Sci USA (2004) 101: 10470-5 [PMID:15240875] |
GAL2 receptor/Galanin receptor 2 in Rat (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL5577] [GtoPdb: 244] [UniProtKB: O08726] | ||||||||
GtoPdb | - | - | 5 | pKd | >10000 | nM | Kd |
Proc Natl Acad Sci USA (2004) 101: 10470-5 [PMID:15240875]; Neuropeptides (2005) 39: 143-6 [PMID:15944002] |
ChEMBL | Binding affinity to rat GalR2 | B | 4 | pKi | >100000 | nM | Ki | J Med Chem (2010) 53: 1871-1875 [PMID:20121116] |
ChEMBL data shown on this page come from version 33:
Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]