bag-2 [Ligand Id: 6189] activity data from GtoPdb and ChEMBL
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| ChEMBL ligand: CHEMBL1084942 |
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| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
|---|---|---|---|---|---|---|---|---|
| BB3 receptor/Bombesin receptor subtype-3 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL4080] [GtoPdb: 40] [UniProtKB: P32247] | ||||||||
| GtoPdb | - | - | 7.02 | pIC50 | 96 | nM | IC50 | Cell Metab (2010) 11: 101-12 [PMID:20096642] |
| ChEMBL | Agonistic activity at human BRS3 expressed in HEK293AEO cells by aequorin bioluminescence assay | F | 6.88 | pEC50 | 133 | nM | EC50 | Bioorg Med Chem Lett (2010) 20: 1913-1917 [PMID:20167483] |
| BB3 receptor/Bombesin receptor subtype-3 in Mouse (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL1075140] [GtoPdb: 40] [UniProtKB: O54798] | ||||||||
| GtoPdb | - | - | 8.18 | pIC50 | 6.6 | nM | IC50 | Cell Metab (2010) 11: 101-12 [PMID:20096642] |
| ChEMBL | Agonistic activity at mouse BRS3 expressed in HEK293AEO cells by aequorin bioluminescence assay | F | 8.1 | pEC50 | 7.9 | nM | EC50 | Bioorg Med Chem Lett (2010) 20: 1913-1917 [PMID:20167483] |
| BB3 receptor in Rat [GtoPdb: 40] [UniProtKB: Q8K418] | ||||||||
| GtoPdb | - | - | 7.99 | pIC50 | 10.3 | nM | IC50 | Cell Metab (2010) 11: 101-12 [PMID:20096642] |
ChEMBL data shown on this page come from version 34:
Zdrazil B, Felix E, Hunter F, Manners EJ, Blackshaw J, Corbett S, de Veij M, Ioannidis H, Lopez DM, Mosquera JF, Magarinos MP, Bosc N, Arcila R, Kizilören T, Gaulton A, Bento AP, Adasme MF, Monecke P, Landrum GA, Leach AR. (2024). The ChEMBL Database in 2023: a drug discovery platform spanning multiple bioactivity data types and time periods. Nucleic Acids Res., 52(D1). DOI: 10.1093/nar/gkad1004. [EPMCID:10767899] [PMID:37933841]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]
