aspirin-triggered resolvin D1 [Ligand Id: 6239] activity data from GtoPdb and ChEMBL

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ChEMBL ligand: CHEMBL519495
  • FPR2/ALX in Human [GtoPdb: 223] [UniProtKB: P25090]
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  • TRPV3 in Human [GtoPdb: 509] [UniProtKB: Q8NET8]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
FPR2/ALX in Human [GtoPdb: 223] [UniProtKB: P25090]
GtoPdb - - 11.1 pEC50 - - - Am J Pathol (2012) 180: 2018-27 [PMID:22449948]
TRPV3 in Human [GtoPdb: 509] [UniProtKB: Q8NET8]
GtoPdb Calcium imaging - 6.4 pIC50 398 nM IC50 Br J Pharmacol (2012) 165: 683-92 [PMID:21718307]

ChEMBL data shown on this page come from version 32:

Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]