aspirin-triggered resolvin D1 [Ligand Id: 6239] activity data from GtoPdb and ChEMBL

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ChEMBL ligand: CHEMBL519495
  • FPR2/ALX in Human [GtoPdb: 223] [UniProtKB: P25090]
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  • TRPV3 in Human [GtoPdb: 509] [UniProtKB: Q8NET8]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
FPR2/ALX in Human [GtoPdb: 223] [UniProtKB: P25090]
GtoPdb - - 11.1 pEC50 - - - Am J Pathol (2012) 180: 2018-27 [PMID:22449948]
TRPV3 in Human [GtoPdb: 509] [UniProtKB: Q8NET8]
GtoPdb Calcium imaging - 6.4 pIC50 398 nM IC50 Br J Pharmacol (2012) 165: 683-92 [PMID:21718307]

ChEMBL data shown on this page come from version 31:

Gaulton A, Hersey A, Nowotka M, Bento AP, Chambers J, Mendez D, Mutowo P, Atkinson F, Bellis LJ, Cibrián-Uhalte E, Davies M, Dedman N, Karlsson A, Magariños MP, Overington JP, Papadatos G, Smit I, Leach AR. (2017) 'The ChEMBL database in 2017.' Nucleic Acids Res., 45(D1). DOI: 10.1093/nar/gkw1074. [PMCID:5210557]