N-acetyl-4-benzoquinoneimine [Ligand Id: 6299] activity data from GtoPdb and ChEMBL
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| ChEMBL ligand: CHEMBL33232 |
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| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
|---|---|---|---|---|---|---|---|---|
| Macrophage migration inhibitory factor in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2085] [UniProtKB: P14174] | ||||||||
| ChEMBL | Inhibition of recombinant human MIF tautomerase activity after 5 to 20 mins in presence of BSA by dopachrome tautomerase assay | B | 4.4 | pIC50 | 40000 | nM | IC50 | J Med Chem (2018) 61: 8104-8119 [PMID:29812929] |
| TRPA1 in Rat [GtoPdb: 485] [UniProtKB: Q6RI86] | ||||||||
| GtoPdb | Calcium imaging | - | 5.6 | pEC50 | - | - | - |
FASEB J (2010) 24: 4904-16 [PMID:20720158]; Nat Commun (2011) 2: 551 [PMID:22109525] |
ChEMBL data shown on this page come from version 33:
Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]
