ChEMBL ligand: CHEMBL13883 (4-hydroxy-3-methoxy-benzyldehyde, FEMA NO. 3107, H-0264, Lioxin, Methylprotocatechuic aldehyde, NPLC-0145, NSC-15351, NSC-403658, NSC-48383, P-hydroxy-m-methoxybenzaldehyde, Rhovanil, Vanillic aldehyde, Vanillin, vanilline, Vanillin melting point standard, Vanillin, natural)
tripartite motif containing 33/E3 ubiquitin-protein ligase TRIM33 in Human [ChEMBL: CHEMBL2176772] [GtoPdb: 2254] [UniProtKB: Q9UPN9] There should be some charts here, you may need to enable JavaScript!
4-aminobutyrate aminotransferase/Gamma-amino-N-butyrate transaminase in Human [ChEMBL: CHEMBL2044] [GtoPdb: 2464] [UniProtKB: P80404] There should be some charts here, you may need to enable JavaScript!
Pancreatic triacylglycerol lipase in Pig [ChEMBL: CHEMBL1687677] [UniProtKB: P00591] There should be some charts here, you may need to enable JavaScript!
aldehyde dehydrogenase 5 family member A1/Succinate semialdehyde dehydrogenase in Human [ChEMBL: CHEMBL1911] [GtoPdb: 2466] [UniProtKB: P51649] There should be some charts here, you may need to enable JavaScript!
tripartite motif containing 24/Transcription intermediary factor 1-alpha in Human [ChEMBL: CHEMBL3108638] [GtoPdb: 2252] [UniProtKB: O15164] There should be some charts here, you may need to enable JavaScript!
TAS2R14 in Human [GtoPdb: 668] [UniProtKB: Q9NYV8] There should be some charts here, you may need to enable JavaScript!
TAS2R20 in Human [GtoPdb: 671] [UniProtKB: P59543] There should be some charts here, you may need to enable JavaScript!
TAS2R39 in Human [GtoPdb: 675] [UniProtKB: P59534] There should be some charts here, you may need to enable JavaScript!

DB	Assay description	Assay Type	Standard value	Standard parameter	Original value	Original units	Original parameter	Reference
tripartite motif containing 33/E3 ubiquitin-protein ligase TRIM33 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2176772] [GtoPdb: 2254] [UniProtKB: Q9UPN9]
ChEMBL	Inhibition of recombinant TRIM33 PHD bromodomain (unknown origin) using biotinylated H3 peptide (H3K9me3K18ac) by AlphaScreen assay	B	6.49	pIC50	325.6	nM	IC50	WO-2018200988-A1. Inhibitors of trim33 and methods of use (2018)
4-aminobutyrate aminotransferase/Gamma-amino-N-butyrate transaminase in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2044] [GtoPdb: 2464] [UniProtKB: P80404]
ChEMBL	Inhibitory activity against GABAT	B	4.77	pIC50	17100	nM	IC50	Bioorg Med Chem Lett (2006) 16: 592-595 [PMID:16290145]
Pancreatic triacylglycerol lipase in Pig (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL1687677] [UniProtKB: P00591]
ChEMBL	Inhibition of pig pancreatic lipase assessed as p-NPB hydrolysis by ELISA	B	4.13	pIC50	74400	nM	IC50	Bioorg Med Chem Lett (2011) 21: 1512-1514 [PMID:21282056]
aldehyde dehydrogenase 5 family member A1/Succinate semialdehyde dehydrogenase in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL1911] [GtoPdb: 2466] [UniProtKB: P51649]
ChEMBL	Inhibitory activity against SSADH	B	4.81	pIC50	15600	nM	IC50	Bioorg Med Chem Lett (2006) 16: 592-595 [PMID:16290145]
tripartite motif containing 24/Transcription intermediary factor 1-alpha in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3108638] [GtoPdb: 2252] [UniProtKB: O15164]
ChEMBL	Inhibition of recombinant TRIM24 (unknown origin) using biotinylated H3 peptide (H3K9me3K18ac) by AlphaScreen assay	B	6.79	pIC50	162	nM	IC50	WO-2018200988-A1. Inhibitors of trim33 and methods of use (2018)
TAS2R14 in Human [GtoPdb: 668] [UniProtKB: Q9NYV8]
GtoPdb	-	-	3.24	pEC50	570000	nM	EC50	Front Nutr (2021) 8: 683627 [PMID:34307435]
TAS2R20 in Human [GtoPdb: 671] [UniProtKB: P59543]
GtoPdb	-	-	3.28	pEC50	530000	nM	EC50	Front Nutr (2021) 8: 683627 [PMID:34307435]
TAS2R39 in Human [GtoPdb: 675] [UniProtKB: P59534]
GtoPdb	-	-	3.06	pEC50	870000	nM	EC50	Front Nutr (2021) 8: 683627 [PMID:34307435]

ChEMBL data shown on this page come from version 34:

Zdrazil B, Felix E, Hunter F, Manners EJ, Blackshaw J, Corbett S, de Veij M, Ioannidis H, Lopez DM, Mosquera JF, Magarinos MP, Bosc N, Arcila R, Kizilören T, Gaulton A, Bento AP, Adasme MF, Monecke P, Landrum GA, Leach AR. (2024). The ChEMBL Database in 2023: a drug discovery platform spanning multiple bioactivity data types and time periods. Nucleic Acids Res., 52(D1). DOI: 10.1093/nar/gkad1004. [EPMCID:10767899] [PMID:37933841]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]