fosinoprilat [Ligand Id: 6457] activity data from GtoPdb and ChEMBL
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| ChEMBL ligand: CHEMBL581 (Fosfenopril, Fosinoprilat, Fosinopril diacid, Fosinoprilic acid, Fosinopril related compound a, PU6BA2D2MD, SO 27,519, SO-27519, SQ 27,519, SQ-27519) |
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| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
|---|---|---|---|---|---|---|---|---|
| Angiotensin-converting enzyme in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL1808] [GtoPdb: 1613] [UniProtKB: P12821] | ||||||||
| ChEMBL | Inhibition of ACE | B | 8.82 | pKi | 1.5 | nM | Ki | J Med Chem (2011) 54: 5955-5980 [PMID:21780776] |
| Angiotensin-converting enzyme in Rabbit (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL4074] [UniProtKB: P12822] | ||||||||
| ChEMBL | Inhibitory activity against rabbit lung angiotensin-1 converting enzyme | B | 8.82 | pKi | 1.5 | nM | Ki | J Med Chem (1988) 31: 1148-1160 [PMID:2836590] |
ChEMBL data shown on this page come from version 33:
Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]
