ethoxzolamide [Ligand Id: 6814] activity data from GtoPdb and ChEMBL

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ChEMBL ligand: CHEMBL18 (Ethoxzolamide, Cardrase, Ethamide)
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  • Alpha carbonic anhydrase in Stylophora pistillata [ChEMBL: CHEMBL1075028] [UniProtKB: B5SU02]
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  • Carbonate dehydratase in Sulfurihydrogenibium sp. (strain YO3AOP1) [ChEMBL: CHEMBL3745586] [UniProtKB: B2V8E3]
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  • Carbonic anhydrase in Mycobacterium tuberculosis [ChEMBL: CHEMBL6068] [UniProtKB: P9WPJ9]
  • Carbonic anhydrase in Methanosarcina thermophila [ChEMBL: CHEMBL3932] [UniProtKB: P40881]
  • Carbonic anhydrase in Stylophora pistillata [ChEMBL: CHEMBL1649055] [UniProtKB: C0IX24]
  • Carbonic anhydrase in Methanobacterium thermoautotrophicum [ChEMBL: CHEMBL3926] [UniProtKB: Q50565]
  • Carbonic anhydrase in Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) [ChEMBL: CHEMBL5337] [UniProtKB: Q5AJ71]
  • Carbonic anhydrase in Candida glabrata CBS 138 [ChEMBL: CHEMBL6185] [UniProtKB: Q6FTL6]
  • Carbonic anhydrase in Saccharomyces cerevisiae S288c [ChEMBL: CHEMBL5931] [UniProtKB: P53615]
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  • Carbonic anhydrase 1 in Helicobacter pylori (strain ATCC 700392 / 26695) (Campylobacterpylori) [ChEMBL: CHEMBL4211] [UniProtKB: O24855]
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  • Carbonic anhydrase 2 in Cryptococcus neoformans var. grubii [ChEMBL: CHEMBL1697676] [UniProtKB: Q3I4V7]
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  • Carbonic anhydrase, alpha family in Thiomicrospira crunogena (strain XCL-2) [ChEMBL: CHEMBL3621035] [UniProtKB: Q31FD6]
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  • carbonic anhydrase 1/Carbonic anhydrase I in Human [ChEMBL: CHEMBL261] [GtoPdb: 2597] [UniProtKB: P00915]
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  • carbonic anhydrase 2/Carbonic anhydrase II in Human [ChEMBL: CHEMBL205] [GtoPdb: 3092] [UniProtKB: P00918]
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  • carbonic anhydrase 4/Carbonic anhydrase IV in Human [ChEMBL: CHEMBL3729] [GtoPdb: 2599] [UniProtKB: P22748]
  • Carbonic anhydrase IV in Bovine [ChEMBL: CHEMBL281] [UniProtKB: Q95323]
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  • carbonic anhydrase 9/Carbonic anhydrase IX in Human [ChEMBL: CHEMBL3594] [GtoPdb: 3055] [UniProtKB: Q16790]
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  • carbonic anhydrase 5A/Carbonic anhydrase VA in Human [ChEMBL: CHEMBL4789] [GtoPdb: 3093] [UniProtKB: P35218]
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  • carbonic anhydrase 7/Carbonic anhydrase VII in Human [ChEMBL: CHEMBL2326] [GtoPdb: 2749] [UniProtKB: P43166]
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  • carbonic anhydrase 12/Carbonic anhydrase XII in Human [ChEMBL: CHEMBL3242] [GtoPdb: 2747] [UniProtKB: O43570]
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  • carbonic anhydrase 13/Carbonic anhydrase XIII in Human [ChEMBL: CHEMBL3912] [GtoPdb: 2748] [UniProtKB: Q8N1Q1]
  • carbonic anhydrase 13/Carbonic anhydrase XIII in Mouse [ChEMBL: CHEMBL2186] [GtoPdb: 2748] [UniProtKB: Q9D6N1]
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  • carbonic anhydrase 14/Carbonic anhydrase XIV in Human [ChEMBL: CHEMBL3510] [GtoPdb: 2598] [UniProtKB: Q9ULX7]
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  • Delta carbonic anhydrase in Thalassiosira weissflogii [ChEMBL: CHEMBL3097982] [UniProtKB: Q5U9J1]
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  • Uncharacterized protein Rv1284/MT1322 in Mycobacterium tuberculosis [ChEMBL: CHEMBL5631] [UniProtKB: P9WPJ7]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
AGAP002992-PA in Anopheles gambiae (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3399914] [UniProtKB: Q5TU56]
ChEMBL Inhibition of Anopheles gambiae carbonic anhydrase pre-incubated for 15 mins by stopped-flow CO2 hydration assay B 6.73 pKi 185 nM Ki Bioorg. Med. Chem. (2015) 23: 2303-2309 [PMID:25882523]
Alpha carbonic anhydrase in Stylophora pistillata (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL1075028] [UniProtKB: B5SU02]
ChEMBL Inhibition of cloned Stylophora pistillata alpha-CA expressed in human HEK293 cells by stopped-flow CO2 assay B 7.4 pKi 39.4 nM Ki Bioorg. Med. Chem. (2009) 17: 5054-5058 [PMID:19520577]
ChEMBL Inhibition of Stylophora pistillata carbonic anhydrase by stopped-flow CO2 hydration assay B 7.4 pKi 39.4 nM Ki Bioorg. Med. Chem. Lett. (2011) 21: 710-714 [PMID:21208801]
Astrosclerin-3 in Astrosclera willeyana (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL1944499] [UniProtKB: A6YCJ1]
ChEMBL Inhibition of GST-tagged astrosclera willeyana Astrosclerin-3 expressed in Escherichia coli after 15 mins preincubation by stopped flow CO2 hydration assay B 6.41 pKi 387 nM Ki Bioorg. Med. Chem. (2012) 20: 1403-1410 [PMID:22285172]
Carbonate dehydratase in Sulfurihydrogenibium sp. (strain YO3AOP1) (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3745586] [UniProtKB: B2V8E3]
ChEMBL Inhibition of recombinant Sulfurihydrogenibium yellowstonense YO3AOP1 carbonic anhydrase by stopped flow CO2 hydrase assay B 8.03 pKi 9.3 nM Ki Bioorg. Med. Chem. Lett. (2016) 26: 401-405 [PMID:26691758]
Carbonic anhydrase in Mycobacterium tuberculosis (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL6068] [UniProtKB: P9WPJ9]
ChEMBL Inhibition of full length Mycobacterium tuberculosis H37Rv recombinant carbonic anhydrase 2 encoded by RV3588c by stopped flow CO2 hydration assay B 7.57 pKi 27 nM Ki Bioorg. Med. Chem. Lett. (2009) 19: 6649-6654 [PMID:19846301]
Carbonic anhydrase in Methanosarcina thermophila (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3932] [UniProtKB: P40881]
ChEMBL Inhibitory activity against alpha carbonic anhydrase (Co-Cam) from Methanosarcina thermophila B 6.13 pKi 740 nM Ki Bioorg. Med. Chem. Lett. (2004) 14: 6001-6006 [PMID:15546717]
ChEMBL Inhibitory activity against alpha carbonic anhydrase (Zn-Cam) from Methanosarcina thermophila B 6.7 pKi 200 nM Ki Bioorg. Med. Chem. Lett. (2004) 14: 6001-6006 [PMID:15546717]
Carbonic anhydrase in Stylophora pistillata (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL1649055] [UniProtKB: C0IX24]
ChEMBL Inhibition of Stylophora pistillata carbonic anhydrase 2 by stopped-flow CO2 hydration assay B 6.98 pKi 105 nM Ki Bioorg. Med. Chem. Lett. (2011) 21: 710-714 [PMID:21208801]
Carbonic anhydrase in Methanobacterium thermoautotrophicum (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3926] [UniProtKB: Q50565]
ChEMBL Inhibitory activity against beta carbonic anhydrase (Cab) from Methanobacterium thermoautotrophicum B 5.27 pKi 5350 nM Ki Bioorg. Med. Chem. Lett. (2004) 14: 6001-6006 [PMID:15546717]
Carbonic anhydrase in Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL5337] [UniProtKB: Q5AJ71]
ChEMBL Inhibition of Candida albicans recombinant Carbonic anhydrase pre-incubated for 15 mins by CO2 hydration stopped-flow assay B 5.97 pKi 1070 nM Ki Bioorg. Med. Chem. Lett. (2009) 19: 2642-2645 [PMID:19375309]
ChEMBL Inhibition of Candida albicans recombinant Nce103 by stopped-flow CO2 hydration assay B 5.97 pKi 1070 nM Ki Bioorg. Med. Chem. (2009) 17: 4503-4509 [PMID:19450983]
ChEMBL inhibition of Candida albicans recombinant Nce103 after 15 mins by stopped-flow CO2 hydration assay B 5.97 pKi 1070 nM Ki Bioorg. Med. Chem. Lett. (2010) 20: 2508-2511 [PMID:20299219]
ChEMBL Inhibition of Candida albicans CaNce103 preincubated for 15 mins measured for 10 to 100 sec by stopped-flow method B 5.97 pKi 1070 nM Ki J. Med. Chem. (2012) 55: 3513-3520 [PMID:22424239]
Carbonic anhydrase in Candida glabrata CBS 138 (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL6185] [UniProtKB: Q6FTL6]
ChEMBL Inhibition of recombinant full length Candida glabrata NCE103 expressed in Escherichia coli BL21 preincubated for 15 mins by stopped-flow CO2 hydrase assay B 5.51 pKi 3125 nM Ki Bioorg. Med. Chem. Lett. (2013) 23: 2647-2652 [PMID:23511020]
Carbonic anhydrase in Saccharomyces cerevisiae S288c (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL5931] [UniProtKB: P53615]
ChEMBL Inhibition of Saccharomyces cerevisiae carbonic anhydrase by oxygen-18 isotope exchange assay B 4.8 pKi 16000 nM Ki Bioorg. Med. Chem. Lett. (2008) 18: 6327-6331 [PMID:18993072]
ChEMBL Inhibition of Saccharomyces cerevisiae recombinant CA expressed in Escherichia coli by stopped-flow CO2 hydrase assay B 7.01 pKi 98.4 nM Ki Bioorg. Med. Chem. (2009) 17: 1158-1163 [PMID:19124253]
Carbonic anhydrase 1 in Helicobacter pylori (strain ATCC 700392 / 26695) (Campylobacterpylori) (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL4211] [UniProtKB: O24855]
ChEMBL Inhibition of Helicobacter pylori recombinant carbonic anhydrase by stopped-flow CO2 hydrase assay B 6.71 pKi 193 nM Ki J. Med. Chem. (2006) 49: 2117-2126 [PMID:16539401]
ChEMBL Inhibition of Helicobacter pylori recombinant CA B 6.81 pKi 155 nM Ki Bioorg. Med. Chem. Lett. (2006) 16: 2182-2188 [PMID:16459077]
Carbonic anhydrase 15 in Mouse (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL5973] [UniProtKB: Q99N23]
ChEMBL Inhibition of mouse recombinant carbonic anhydrase 15 by stopped flow CO2 hydrase assay B 7.24 pKi 58 nM Ki J. Med. Chem. (2009) 52: 646-654 [PMID:19193158]
ChEMBL Inhibition of full length mouse carbonic anhydrase 15 preincubated for 15 mins by CO2 hydration stopped-flow assay B 7.24 pKi 58 nM Ki Bioorg. Med. Chem. Lett. (2010) 20: 3601-3605 [PMID:20472429]
Carbonic anhydrase 2 in Cryptococcus neoformans var. grubii (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL1697676] [UniProtKB: Q3I4V7]
ChEMBL Inhibition of Cryptococcus neoformans Can2 preincubated for 15 mins measured for 10 to 100 sec by stopped-flow method B 7.06 pKi 87 nM Ki J. Med. Chem. (2012) 55: 3513-3520 [PMID:22424239]
Carbonic anhydrase 3 in Bovine (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL1944498] [UniProtKB: Q3SZX4]
ChEMBL Inhibition of bovine carbonic anhydrase 3 using 4-nitrophenylacetate as substrate after 3 mins using spectrophotometry by Lineweaver-Burk plot analysis B 5.02 pKi 9443 nM Ki Eur. J. Med. Chem. (2012) 49: 68-73 [PMID:22245047]
Carbonic anhydrase, alpha family in Thiomicrospira crunogena (strain XCL-2) (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3621035] [UniProtKB: Q31FD6]
ChEMBL Inhibition of recombinant Thiomicrospira crunogena XCL-2 carbonic anhydrase by stopped flow CO2 hydrase assay B 8.39 pKi 4.1 nM Ki Bioorg. Med. Chem. Lett. (2016) 26: 401-405 [PMID:26691758]
carbonic anhydrase 1/Carbonic anhydrase I in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL261] [GtoPdb: 2597] [UniProtKB: P00915]
ChEMBL Binding affinity to human recombinant CA1 at 37 degC and pH 7.0 by thermal shift assay B 7.85 pKd 14 nM Kd Bioorg. Med. Chem. (2013) 21: 2093-2106 [PMID:23394791]
ChEMBL Binding affinity to human recombinant carbonic anhydrase 1 expressed in Escherichia coli BL21 (DE3) by thermal shift assay B 7.85 pKd 14 nM Kd Bioorg. Med. Chem. (2013) 21: 6937-6947 [PMID:24103428]
ChEMBL Inhibition of human carbonic anhydrase 1 using 4-nitrophenylacetate as substrate after 3 mins using spectrophotometry by Lineweaver-Burk plot analysis B 5.43 pKi 3750 nM Ki Eur. J. Med. Chem. (2012) 49: 68-73 [PMID:22245047]
ChEMBL Inhibition of human carbonic anhydrase 1 esterase activity using 4-nitrophenylacetate as substrate B 5.43 pKi 3750 nM Ki Bioorg. Med. Chem. Lett. (2012) 22: 1352-1357 [PMID:22230050]
ChEMBL Inhibitory potency against human cloned Carbonic anhydrase I expressed in Escherichia coli strain BL21 B 5.92 pKi 1200 nM Ki Bioorg. Med. Chem. Lett. (2005) 15: 367-372 [PMID:15603956]
ChEMBL Inhibition of human cytosolic carbonic anhydrase 1 preincubated for 15 mins by stopped flow CO2 hydration assay B 7.6 pKi 25.2 nM Ki Bioorg. Med. Chem. Lett. (2014) 24: 1310-1314 [PMID:24507918]
GtoPdb - - 7.6 pKi 25 nM Ki Bioorg Med Chem Lett (2005) 15: 1149-54 [PMID:15686931];
Bioorg Med Chem Lett (2005) 15: 963-9 [PMID:15686894]
ChEMBL Inhibition of human recombinant carbonic anhydrase I (CA1) B 7.6 pKi 25 nM Ki J. Med. Chem. (2000) 43: 4542-4551 [PMID:11087579]
ChEMBL Inhibition of cloned human cytosolic isozyme Carbonic anhydrase I B 7.6 pKi 25 nM Ki J. Med. Chem. (2004) 47: 1272-1279 [PMID:14971907]
ChEMBL Inhibitory activity against human cloned isoenzyme carbonic anhydrase I (hCA I), by esterase method. B 7.6 pKi 25 nM Ki Bioorg. Med. Chem. Lett. (2003) 13: 837-840 [PMID:12617903]
ChEMBL Inhibitory activity against human cloned carbonic anhydrase I (hCA I) B 7.6 pKi 25 nM Ki Bioorg. Med. Chem. Lett. (2003) 13: 841-845 [PMID:12617904]
ChEMBL Inhibitory activity against human cloned carbonic anhydrase isozyme I by esterase assay method. B 7.6 pKi 25 nM Ki Bioorg. Med. Chem. Lett. (2003) 13: 1005-1009 [PMID:12643899]
ChEMBL Inhibitory activity against human carbonic anhydrase I B 7.6 pKi 25 nM Ki Bioorg. Med. Chem. Lett. (2004) 14: 2351-2356 [PMID:15081039]
ChEMBL Inhibitory activity against human recombinant carbonic anhydrase I (CA1) B 7.6 pKi 25 nM Ki Bioorg. Med. Chem. Lett. (2002) 12: 1551-1557 [PMID:12039560]
ChEMBL Inhibition of human recombinant carbonic anhydrase I B 7.6 pKi 25 nM Ki J. Med. Chem. (2003) 46: 2197-2204 [PMID:12747791]
ChEMBL Inhibitory activity against human carbonic anhydrase I. B 7.6 pKi 25 nM Ki J. Med. Chem. (2003) 46: 5471-5477 [PMID:14640555]
ChEMBL In vitro inhibitory activity against human carbonic anhydrase I (hCAI) B 7.6 pKi 25 nM Ki J. Med. Chem. (2004) 47: 2796-2804 [PMID:15139757]
ChEMBL Inhibitory activity against Human carbonic anhydrase I B 7.6 pKi 25 nM Ki J. Med. Chem. (2002) 45: 1466-1476 [PMID:11906288]
ChEMBL Inhibitory activity against Carbonic anhydrase I B 7.6 pKi 25 nM Ki J. Med. Chem. (2005) 48: 2121-2125 [PMID:15771455]
ChEMBL Ki value against human carbonic anhydrase I (hCA I) B 7.6 pKi 25 nM Ki Bioorg. Med. Chem. Lett. (2005) 15: 963-969 [PMID:15686894]
ChEMBL Inhibitory activity against human carbonic anhydrase I B 7.6 pKi 25 nM Ki Bioorg. Med. Chem. Lett. (2005) 15: 3821-3827 [PMID:16039853]
ChEMBL Inhibitory activity against cytosolic human carbonic anhydrase I B 7.6 pKi 25 nM Ki Bioorg. Med. Chem. Lett. (2005) 15: 579-584 [PMID:15664816]
ChEMBL Ki value against human carbonic anhydrase I B 7.6 pKi 25 nM Ki Bioorg. Med. Chem. Lett. (2005) 15: 971-976 [PMID:15686895]
ChEMBL Inhibitory activity against human carbonic anhydrase I (hCAI) B 7.6 pKi 25 nM Ki Bioorg. Med. Chem. Lett. (2005) 15: 1149-1154 [PMID:15686931]
ChEMBL Inhibitory activity against human carbonic anhydrase I expressed in Escherichia coli BL21 B 7.6 pKi 25 nM Ki Bioorg. Med. Chem. Lett. (2004) 14: 5427-5433 [PMID:15454239]
ChEMBL Binding affinity towards human cloned carbonic anhydrase I B 7.6 pKi 25 nM Ki Bioorg. Med. Chem. Lett. (2004) 14: 5775-5780 [PMID:15501039]
ChEMBL Inhibitory activity against human carbonic anhydrase I at 0.09 uM B 7.6 pKi 25 nM Ki Bioorg. Med. Chem. Lett. (2004) 14: 6001-6006 [PMID:15546717]
ChEMBL Inhibitory activity against human Carbonic anhydrase I B 7.6 pKi 25 nM Ki J. Med. Chem. (2004) 47: 5224-5229 [PMID:15456265]
ChEMBL Inhibitory constant against human Carbonic anhydrase I B 7.6 pKi 25 nM Ki Bioorg. Med. Chem. Lett. (2005) 15: 3102-3108 [PMID:15905091]
ChEMBL Inhibition constant against human (cloned) isozyme (hCA I) by the CO2 hydration method B 7.6 pKi 25 nM Ki J. Med. Chem. (2005) 48: 4834-4841 [PMID:16033263]
ChEMBL Inhibition constant against human recombinant carbonic anhydrase I F 7.6 pKi 25 nM Ki Bioorg. Med. Chem. Lett. (2005) 15: 3302-3306 [PMID:15908201]
ChEMBL Inhibitory constant against human Carbonic anhydrase I B 7.6 pKi 25 nM Ki Bioorg. Med. Chem. Lett. (2005) 15: 2359-2364 [PMID:15837325]
ChEMBL Inhibition constant against human carbonic anhydrase I B 7.6 pKi 25 nM Ki Bioorg. Med. Chem. Lett. (2005) 15: 3096-3101 [PMID:15908204]
ChEMBL Inhibitory activity against human Carbonic anhydrase I (hCA I) B 7.6 pKi 25 nM Ki Bioorg. Med. Chem. Lett. (2005) 15: 4862-4866 [PMID:16168653]
ChEMBL Inhibitory activity against human cloned Carbonic anhydrase I by the CO2 hydration method B 7.6 pKi 25 nM Ki Bioorg. Med. Chem. Lett. (2005) 15: 4872-4876 [PMID:16165351]
ChEMBL Inhibition of human recombinant carbonic anhydrase 1 by stopped-flow CO2 hydrase assay B 7.6 pKi 25 nM Ki J. Med. Chem. (2006) 49: 2117-2126 [PMID:16539401]
ChEMBL Inhibition of human recombinant CA1 B 7.6 pKi 25 nM Ki Bioorg. Med. Chem. Lett. (2006) 16: 2182-2188 [PMID:16459077]
ChEMBL Inhibition of human recombinant carbonic anhydrase 1 by stopped-flow CO2 hydrase assay B 7.6 pKi 25 nM Ki J. Med. Chem. (2006) 49: 5544-5551 [PMID:16942027]
ChEMBL Inhibition of human cloned CA1 by CO2 hydration assay B 7.6 pKi 25 nM Ki Bioorg. Med. Chem. Lett. (2006) 16: 4846-4851 [PMID:16809036]
ChEMBL Inhibition of human cloned CA1 by CO2 hydration method B 7.6 pKi 25 nM Ki J. Med. Chem. (2006) 49: 6539-6548 [PMID:17064072]
ChEMBL Inhibition of human cloned CA1 by stopped-flow CO2 hydration method B 7.6 pKi 25 nM Ki J. Med. Chem. (2006) 49: 7024-7031 [PMID:17125255]
ChEMBL Inhibition of human recombinant cytosolic isozyme CA I by stopped-flow CO2 hydrase method B 7.6 pKi 25 nM Ki J. Med. Chem. (2007) 50: 381-388 [PMID:17228881]
ChEMBL Inhibition of human recombinant isozyme CA1 by CO2 hydration method B 7.6 pKi 25 nM Ki J. Med. Chem. (2007) 50: 1651-1657 [PMID:17343373]
ChEMBL Inhibition of human recombinant carbonic anhydrase 1 by CO2 hydration method B 7.6 pKi 25 nM Ki Bioorg. Med. Chem. (2007) 15: 2298-2311 [PMID:17276072]
ChEMBL Inhibition of human cloned CA1 by CO2 hydration method B 7.6 pKi 25 nM Ki Bioorg. Med. Chem. Lett. (2007) 17: 5032-5035 [PMID:17681760]
ChEMBL Inhibition of human carbonic anhydrase 1 B 7.6 pKi 25 nM Ki Bioorg. Med. Chem. (2007) 15: 4336-4350 [PMID:17475500]
ChEMBL Inhibition of human recombinant CA1 by CO2 hydration stopped flow assay B 7.6 pKi 25 nM Ki Bioorg. Med. Chem. Lett. (2008) 18: 836-841 [PMID:18042384]
ChEMBL Inhibition of human cloned CA1 by CO2 hydration method B 7.6 pKi 25 nM Ki J. Med. Chem. (2008) 51: 1945-1953 [PMID:18307288]
ChEMBL Inhibition of human full length carbonic anhydrase 1 by stopped flow CO2 hydrase assay B 7.6 pKi 25 nM Ki Bioorg. Med. Chem. Lett. (2008) 18: 2669-2674 [PMID:18359629]
ChEMBL Inhibition of human recombinant carbonic anhydrase 1 by CO2 hydration stopped-flow assay B 7.6 pKi 25 nM Ki Bioorg. Med. Chem. Lett. (2008) 18: 3475-3480 [PMID:18513964]
ChEMBL Inhibition of human recombinant full length CA1 expressed in Escherichia coli BL21 (DE3) by stopped flow CO2 hydration assay B 7.6 pKi 25 nM Ki Bioorg. Med. Chem. Lett. (2009) 19: 1371-1375 [PMID:19186056]
ChEMBL Inhibition of human recombinant carbonic anhydrase 1 by stopped flow CO2 hydration method