methazolamide [Ligand Id: 6828] activity data from GtoPdb and ChEMBL

Click here for a description of the charts and data table

Please tell us if you are using this feature and what you think!

ChEMBL ligand: CHEMBL1335656
  • carbonic anhydrase 1 in Human [GtoPdb: 2597] [UniProtKB: P00915]
  • This target only has 1 pki data point
1 CHEMBL1335656_lig_chart_1 carbonic anhydrase 1 Human
There should be some charts here, you may need to enable JavaScript!
  • carbonic anhydrase 14 in Human [GtoPdb: 2598] [UniProtKB: Q9ULX7]
  • This target only has 1 pki data point
2 CHEMBL1335656_lig_chart_2 carbonic anhydrase 14 Human
There should be some charts here, you may need to enable JavaScript!
  • carbonic anhydrase 4 in Human [GtoPdb: 2599] [UniProtKB: P22748]
  • This target only has 1 pki data point
3 CHEMBL1335656_lig_chart_3 carbonic anhydrase 4 Human
There should be some charts here, you may need to enable JavaScript!
  • carbonic anhydrase 12 in Human [GtoPdb: 2747] [UniProtKB: O43570]
  • This target only has 1 pki data point
4 CHEMBL1335656_lig_chart_4 carbonic anhydrase 12 Human
There should be some charts here, you may need to enable JavaScript!
  • carbonic anhydrase 7 in Human [GtoPdb: 2749] [UniProtKB: P43166]
  • This target only has 1 pki data point
5 CHEMBL1335656_lig_chart_5 carbonic anhydrase 7 Human
There should be some charts here, you may need to enable JavaScript!
DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
carbonic anhydrase 1 in Human [GtoPdb: 2597] [UniProtKB: P00915]
GtoPdb - - 7.48 pKi 33 nM Ki Bioorg. Med. Chem. Lett. (2005) 15: 3828-33 [PMID:16039848];
Bioorg. Med. Chem. Lett. (2005) 15: 963-9 [PMID:15686894]
carbonic anhydrase 14 in Human [GtoPdb: 2598] [UniProtKB: Q9ULX7]
GtoPdb - - 7.57 pKi 27 nM Ki Bioorg. Med. Chem. Lett. (2005) 15: 3828-33 [PMID:16039848]
carbonic anhydrase 4 in Human [GtoPdb: 2599] [UniProtKB: P22748]
GtoPdb - - 7.62 pKi 24 nM Ki Bioorg. Med. Chem. Lett. (2005) 15: 3828-33 [PMID:16039848]
carbonic anhydrase 12 in Human [GtoPdb: 2747] [UniProtKB: O43570]
GtoPdb - - 8.47 pKi 3.4 nM Ki Bioorg. Med. Chem. Lett. (2005) 15: 963-9 [PMID:15686894]
carbonic anhydrase 7 in Human [GtoPdb: 2749] [UniProtKB: P43166]
GtoPdb - - 8.68 pKi 2.1 nM Ki Bioorg. Med. Chem. (2013) 21: 5973-82 [PMID:23965175]

ChEMBL data shown on this page come from version 27:

Gaulton A, Hersey A, Nowotka M, Bento AP, Chambers J, Mendez D, Mutowo P, Atkinson F, Bellis LJ, Cibrián-Uhalte E, Davies M, Dedman N, Karlsson A, Magariños MP, Overington JP, Papadatos G, Smit I, Leach AR. (2017) 'The ChEMBL database in 2017.' Nucleic Acids Res., 45(D1). DOI: 10.1093/nar/gkw1074. [PMCID:5210557]