methazolamide [Ligand Id: 6828] activity data from GtoPdb and ChEMBL
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| ChEMBL ligand: CHEMBL1335656 |
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| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
|---|---|---|---|---|---|---|---|---|
| carbonic anhydrase 1 in Human [GtoPdb: 2597] [UniProtKB: P00915] | ||||||||
| GtoPdb | - | - | 7.48 | pKi | 33 | nM | Ki |
Bioorg Med Chem Lett (2005) 15: 3828-33 [PMID:16039848]; Bioorg Med Chem Lett (2005) 15: 963-9 [PMID:15686894] |
| carbonic anhydrase 14 in Human [GtoPdb: 2598] [UniProtKB: Q9ULX7] | ||||||||
| GtoPdb | - | - | 7.57 | pKi | 27 | nM | Ki | Bioorg Med Chem Lett (2005) 15: 3828-33 [PMID:16039848] |
| carbonic anhydrase 4 in Human [GtoPdb: 2599] [UniProtKB: P22748] | ||||||||
| GtoPdb | - | - | 7.62 | pKi | 24 | nM | Ki | Bioorg Med Chem Lett (2005) 15: 3828-33 [PMID:16039848] |
| carbonic anhydrase 12 in Human [GtoPdb: 2747] [UniProtKB: O43570] | ||||||||
| GtoPdb | - | - | 8.47 | pKi | 3.4 | nM | Ki | Bioorg Med Chem Lett (2005) 15: 963-9 [PMID:15686894] |
| carbonic anhydrase 7 in Human [GtoPdb: 2749] [UniProtKB: P43166] | ||||||||
| GtoPdb | - | - | 8.68 | pKi | 2.1 | nM | Ki | Bioorg Med Chem (2013) 21: 5973-82 [PMID:23965175] |
ChEMBL data shown on this page come from version 33:
Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]
