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ChEMBL ligand: CHEMBL783 (A-4166, AY4166, AY-4166, DJN 608, DJN-608, D-nateglinide, Nateglinide, NSC-758695, SDZ DJN 608, SDZ-DJN-608, Senaglinide, Starlix, Starsis) |
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DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
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Peptide transporter 2/Oligopeptide transporter, kidney isoform in Rat (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3325] [GtoPdb: 985] [UniProtKB: Q63424] | ||||||||
ChEMBL | TP_TRANSPORTER: inhibition of Gly-Sar uptake (Gly-Sar: 20 uM) in PEPT2-expressing LLC-PK1 cells | F | 4.15 | pIC50 | 70000 | nM | IC50 | Eur. J. Pharmacol. (2000) 392: 11-17 [PMID:10748266] |
Organic anion transporter 1/Solute carrier family 22 member 6 in Rat (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL1777665] [GtoPdb: 1025] [UniProtKB: O35956] | ||||||||
ChEMBL | Inhibition of rat Oat1 expressed in Xenopus oocytes | B | 5.04 | pKi | 9200 | nM | Ki | Bioorg. Med. Chem. (2011) 19: 3320-3340 [PMID:21571536] |
ChEMBL | TP_TRANSPORTER: inhibition of PAH uptake in Xenopus laevis oocytes | F | 5.04 | pKi | 9200 | nM | Ki | Eur. J. Pharmacol. (2000) 398: 193-197 [PMID:10854830] |
ChEMBL data shown on this page come from version 31:
Gaulton A, Hersey A, Nowotka M, Bento AP, Chambers J, Mendez D, Mutowo P, Atkinson F, Bellis LJ, CibriƔn-Uhalte E, Davies M, Dedman N, Karlsson A, MagariƱos MP, Overington JP, Papadatos G, Smit I, Leach AR. (2017) 'The ChEMBL database in 2017.' Nucleic Acids Res., 45(D1). DOI: 10.1093/nar/gkw1074. [PMCID:5210557]