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ChEMBL ligand: CHEMBL1201258 |
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DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
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dihydrofolate reductase in Human [GtoPdb: 2603] [UniProtKB: P00374] | ||||||||
GtoPdb | - | - | 8.15 | pKi | 7 | nM | Ki |
J Med Chem (2005) 48: 5329-36 [PMID:16078850]; Adv Enzyme Regul (1998) 38: 135-52 [PMID:9762351] |
phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase in Mouse [GtoPdb: 2612] [UniProtKB: Q64737] | ||||||||
GtoPdb | - | - | 5.03 | pKi | 9300 | nM | Ki | Adv Enzyme Regul (1998) 38: 135-52 [PMID:9762351] |
thymidylate synthetase in Human [GtoPdb: 2642] [UniProtKB: P04818] | ||||||||
GtoPdb | - | - | 6.96 | pKi | 109 | nM | Ki | Adv Enzyme Regul (1998) 38: 135-52 [PMID:9762351] |
ChEMBL data shown on this page come from version 28:
Gaulton A, Hersey A, Nowotka M, Bento AP, Chambers J, Mendez D, Mutowo P, Atkinson F, Bellis LJ, CibriƔn-Uhalte E, Davies M, Dedman N, Karlsson A, MagariƱos MP, Overington JP, Papadatos G, Smit I, Leach AR. (2017) 'The ChEMBL database in 2017.' Nucleic Acids Res., 45(D1). DOI: 10.1093/nar/gkw1074. [PMCID:5210557]