calcitonin [Ligand Id: 685] activity data from GtoPdb and ChEMBL

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ChEMBL ligand: CHEMBL1201614
  • CT receptor in Human [GtoPdb: 43] [UniProtKB: P30988]
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  • AMY1 receptor in Human [GtoPdb: 44]
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  • AMY2 receptor in Human [GtoPdb: 45]
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  • AMY3 receptor in Human [GtoPdb: 46]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
CT receptor in Human [GtoPdb: 43] [UniProtKB: P30988]
GtoPdb - - 11.2 pEC50 - - - Mol Pharmacol (2005) 67: 1655-65 [PMID:15692146];
Endocrinology (1995) 136: 5377-84 [PMID:7588285];
Biochem J (2000) 351: 347-351 [PMID:11023820];
Biochem Biophys Res Commun (2003) 301: 460-4 [PMID:12565884];
Endocrinology (1999) 140: 2924-7 [PMID:10342886];
J Pharmacol Toxicol Methods (1999) 42: 217-24 [PMID:11033437]
AMY1 receptor in Human [GtoPdb: 44]
GtoPdb - - 11.3 pEC50 - - - Mol Pharmacol (2005) 67: 1655-65 [PMID:15692146];
Biochem J (2000) 351: 347-351 [PMID:11023820];
J Pharmacol Toxicol Methods (1999) 42: 217-24 [PMID:11033437]
AMY2 receptor in Human [GtoPdb: 45]
GtoPdb - - 11.4 pEC50 - - - J Pharmacol Toxicol Methods (1999) 42: 217-24 [PMID:11033437]
AMY3 receptor in Human [GtoPdb: 46]
GtoPdb - - 10.6 pEC50 - - - J Pharmacol Toxicol Methods (1999) 42: 217-24 [PMID:11033437]

ChEMBL data shown on this page come from version 32:

Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]