calcitonin [Ligand Id: 685] activity data from GtoPdb and ChEMBL

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ChEMBL ligand: CHEMBL1201614 (Calcitonin (human synthetic), Cibacalcin, Calcitonin Human, Calcitonin human)
  • CT receptor in Human [GtoPdb: 43] [UniProtKB: P30988]
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  • AMY1 receptor in Human [GtoPdb: 44]
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  • AMY2 receptor in Human [GtoPdb: 45]
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  • AMY3 receptor in Human [GtoPdb: 46]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
CT receptor in Human [GtoPdb: 43] [UniProtKB: P30988]
GtoPdb - - 11.2 pEC50 - - - Mol. Pharmacol. (2005) 67: 1655-65 [PMID:15692146];
Endocrinology (1995) 136: 5377-84 [PMID:7588285];
Biochem J. (2000) 351: 347-351 [PMID:11023820];
Biochem. Biophys. Res. Commun. (2003) 301: 460-4 [PMID:12565884];
Endocrinology (1999) 140: 2924-7 [PMID:10342886];
J Pharmacol Toxicol Methods (1999) 42: 217-24 [PMID:11033437]
AMY1 receptor in Human [GtoPdb: 44]
GtoPdb - - 11.3 pEC50 - - - Mol. Pharmacol. (2005) 67: 1655-65 [PMID:15692146];
Biochem J. (2000) 351: 347-351 [PMID:11023820];
J Pharmacol Toxicol Methods (1999) 42: 217-24 [PMID:11033437]
AMY2 receptor in Human [GtoPdb: 45]
GtoPdb - - 11.4 pEC50 - - - J Pharmacol Toxicol Methods (1999) 42: 217-24 [PMID:11033437]
AMY3 receptor in Human [GtoPdb: 46]
GtoPdb - - 10.6 pEC50 - - - J Pharmacol Toxicol Methods (1999) 42: 217-24 [PMID:11033437]

ChEMBL data shown on this page come from version 27:

Gaulton A, Hersey A, Nowotka M, Bento AP, Chambers J, Mendez D, Mutowo P, Atkinson F, Bellis LJ, CibriƔn-Uhalte E, Davies M, Dedman N, Karlsson A, MagariƱos MP, Overington JP, Papadatos G, Smit I, Leach AR. (2017) 'The ChEMBL database in 2017.' Nucleic Acids Res., 45(D1). DOI: 10.1093/nar/gkw1074. [PMCID:5210557]