NAEPA [Ligand Id: 6982] activity data from GtoPdb and ChEMBL

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ChEMBL ligand: CHEMBL1574292
  • LPA1 receptor in Mouse [GtoPdb: 272] [UniProtKB: P61793]
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  • LPA2 receptor in Mouse [GtoPdb: 273] [UniProtKB: Q9JL06]
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  • LPA3 receptor in Mouse [GtoPdb: 274] [UniProtKB: Q9EQ31]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
LPA1 receptor in Mouse [GtoPdb: 272] [UniProtKB: P61793]
GtoPdb - - 6.71 pEC50 197 nM EC50 Curr Med Chem (2008) 15: 2122-31 [PMID:18781939]
LPA2 receptor in Mouse [GtoPdb: 273] [UniProtKB: Q9JL06]
GtoPdb - - 7.52 pEC50 30 nM EC50 Curr Med Chem (2008) 15: 2122-31 [PMID:18781939]
LPA3 receptor in Mouse [GtoPdb: 274] [UniProtKB: Q9EQ31]
GtoPdb - - 5.3 pEC50 >5000 nM EC50 Curr Med Chem (2008) 15: 2122-31 [PMID:18781939]

ChEMBL data shown on this page come from version 32:

Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]