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ChEMBL ligand: CHEMBL131556 |
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DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
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D2 receptor/Dopamine D2 receptor in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL217] [GtoPdb: 215] [UniProtKB: P14416] | ||||||||
ChEMBL | Binding affinity against human Dopamine receptor D2 in mouse LtK- cells using [3H]spiperone. | B | 6.3 | pKi | 501.19 | nM | Ki | Bioorg. Med. Chem. Lett. (1996) 6: 403-408 |
D3 receptor/Dopamine D3 receptor in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL234] [GtoPdb: 216] [UniProtKB: P35462] | ||||||||
ChEMBL | Binding affinity against human Dopamine receptor D3 in Chinese hamster ovary cells using [3H]spiperone. | B | 8.9 | pKi | 1.26 | nM | Ki | Bioorg. Med. Chem. Lett. (1996) 6: 403-408 |
5-HT1A receptor in Human [GtoPdb: 1] [UniProtKB: P08908] | ||||||||
GtoPdb | - | - | 6.8 | pKi | - | - | - | J Pharmacol Exp Ther (2000) 293: 1048-62 [PMID:10869410] |
ChEMBL data shown on this page come from version 31:
Gaulton A, Hersey A, Nowotka M, Bento AP, Chambers J, Mendez D, Mutowo P, Atkinson F, Bellis LJ, CibriƔn-Uhalte E, Davies M, Dedman N, Karlsson A, MagariƱos MP, Overington JP, Papadatos G, Smit I, Leach AR. (2017) 'The ChEMBL database in 2017.' Nucleic Acids Res., 45(D1). DOI: 10.1093/nar/gkw1074. [PMCID:5210557]