ChEMBL ligand: CHEMBL77517 (E7070, E-7070, Indisulam)
AGAP002992-PA in Anopheles gambiae [ChEMBL: CHEMBL3399914] [UniProtKB: Q5TU56] There should be some charts here, you may need to enable JavaScript!
Alpha carbonic anhydrase in Stylophora pistillata [ChEMBL: CHEMBL1075028] [UniProtKB: B5SU02] There should be some charts here, you may need to enable JavaScript!
Astrosclerin-3 in Astrosclera willeyana [ChEMBL: CHEMBL1944499] [UniProtKB: A6YCJ1] There should be some charts here, you may need to enable JavaScript!
Carbonate dehydratase in Sulfurihydrogenibium sp. (strain YO3AOP1) [ChEMBL: CHEMBL3745586] [UniProtKB: B2V8E3] There should be some charts here, you may need to enable JavaScript!
Carbonic anhydrase in Mycobacterium tuberculosis [ChEMBL: CHEMBL6068] [UniProtKB: P9WPJ9] Carbonic anhydrase in Stylophora pistillata [ChEMBL: CHEMBL1649055] [UniProtKB: C0IX24] Carbonic anhydrase in Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) [ChEMBL: CHEMBL5337] [UniProtKB: Q5AJ71] Carbonic anhydrase in Candida glabrata CBS 138 [ChEMBL: CHEMBL6185] [UniProtKB: Q6FTL6] Carbonic anhydrase in Saccharomyces cerevisiae S288c [ChEMBL: CHEMBL5931] [UniProtKB: P53615] There should be some charts here, you may need to enable JavaScript!
Carbonic anhydrase 1 in Helicobacter pylori (strain ATCC 700392 / 26695) (Campylobacterpylori) [ChEMBL: CHEMBL4211] [UniProtKB: O24855] There should be some charts here, you may need to enable JavaScript!
Carbonic anhydrase 15 in Mouse [ChEMBL: CHEMBL5973] [UniProtKB: Q99N23] There should be some charts here, you may need to enable JavaScript!
Carbonic anhydrase 2 in Cryptococcus neoformans var. grubii [ChEMBL: CHEMBL1697676] [UniProtKB: Q3I4V7] There should be some charts here, you may need to enable JavaScript!
Carbonic anhydrase, alpha family in Thiomicrospira crunogena (strain XCL-2) [ChEMBL: CHEMBL3621035] [UniProtKB: Q31FD6] There should be some charts here, you may need to enable JavaScript!
carbonic anhydrase 1/Carbonic anhydrase I in Human [ChEMBL: CHEMBL261] [GtoPdb: 2597] [UniProtKB: P00915] There should be some charts here, you may need to enable JavaScript!
carbonic anhydrase 2/Carbonic anhydrase II in Human [ChEMBL: CHEMBL205] [GtoPdb: 3092] [UniProtKB: P00918] There should be some charts here, you may need to enable JavaScript!
Carbonic anhydrase III in Human [ChEMBL: CHEMBL2885] [UniProtKB: P07451] There should be some charts here, you may need to enable JavaScript!
Carbonic anhydrase IV in Bovine [ChEMBL: CHEMBL281] [UniProtKB: Q95323] There should be some charts here, you may need to enable JavaScript!
carbonic anhydrase 9/Carbonic anhydrase IX in Human [ChEMBL: CHEMBL3594] [GtoPdb: 3055] [UniProtKB: Q16790] There should be some charts here, you may need to enable JavaScript!
carbonic anhydrase 5A/Carbonic anhydrase VA in Human [ChEMBL: CHEMBL4789] [GtoPdb: 3093] [UniProtKB: P35218] There should be some charts here, you may need to enable JavaScript!
Carbonic anhydrase VB in Human [ChEMBL: CHEMBL3969] [UniProtKB: Q9Y2D0] There should be some charts here, you may need to enable JavaScript!
Carbonic anhydrase VI in Human [ChEMBL: CHEMBL3025] [UniProtKB: P23280] There should be some charts here, you may need to enable JavaScript!
carbonic anhydrase 7/Carbonic anhydrase VII in Human [ChEMBL: CHEMBL2326] [GtoPdb: 2749] [UniProtKB: P43166] There should be some charts here, you may need to enable JavaScript!
carbonic anhydrase 12/Carbonic anhydrase XII in Human [ChEMBL: CHEMBL3242] [GtoPdb: 2747] [UniProtKB: O43570] There should be some charts here, you may need to enable JavaScript!
carbonic anhydrase 14/Carbonic anhydrase XIV in Human [ChEMBL: CHEMBL3510] [GtoPdb: 2598] [UniProtKB: Q9ULX7] There should be some charts here, you may need to enable JavaScript!
Delta carbonic anhydrase in Thalassiosira weissflogii [ChEMBL: CHEMBL3097982] [UniProtKB: Q5U9J1] There should be some charts here, you may need to enable JavaScript!
PROBABLE TRANSMEMBRANE CARBONIC ANHYDRASE (CARBONATE DEHYDRATASE) (CARBONIC DEHYDRATASE) in Mycobacterium tuberculosis [ChEMBL: CHEMBL5767] [UniProtKB: P96878] There should be some charts here, you may need to enable JavaScript!
Uncharacterized protein Rv1284/MT1322 in Mycobacterium tuberculosis [ChEMBL: CHEMBL5631] [UniProtKB: P9WPJ7] There should be some charts here, you may need to enable JavaScript!

DB	Assay description	Assay Type	Standard value	Standard parameter	Original value	Original units	Original parameter	Reference
AGAP002992-PA in Anopheles gambiae (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3399914] [UniProtKB: Q5TU56]
ChEMBL	Inhibition of Anopheles gambiae carbonic anhydrase pre-incubated for 15 mins by stopped-flow CO2 hydration assay	B	6.65	pKi	226	nM	Ki	Bioorg Med Chem (2015) 23: 2303-2309 [PMID:25882523]
Alpha carbonic anhydrase in Stylophora pistillata (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL1075028] [UniProtKB: B5SU02]
ChEMBL	Inhibition of cloned Stylophora pistillata alpha-CA expressed in human HEK293 cells by stopped-flow CO2 assay	B	6.79	pKi	163	nM	Ki	Bioorg Med Chem (2009) 17: 5054-5058 [PMID:19520577]
ChEMBL	Inhibition of Stylophora pistillata carbonic anhydrase by stopped-flow CO2 hydration assay	B	6.79	pKi	163	nM	Ki	Bioorg Med Chem Lett (2011) 21: 710-714 [PMID:21208801]
Astrosclerin-3 in Astrosclera willeyana (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL1944499] [UniProtKB: A6YCJ1]
ChEMBL	Inhibition of GST-tagged astrosclera willeyana Astrosclerin-3 expressed in Escherichia coli after 15 mins preincubation by stopped flow CO2 hydration assay	B	6.37	pKi	423	nM	Ki	Bioorg Med Chem (2012) 20: 1403-1410 [PMID:22285172]
Carbonate dehydratase in Sulfurihydrogenibium sp. (strain YO3AOP1) (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3745586] [UniProtKB: B2V8E3]
ChEMBL	Inhibition of recombinant Sulfurihydrogenibium yellowstonense YO3AOP1 carbonic anhydrase by stopped flow CO2 hydrase assay	B	7.08	pKi	84.1	nM	Ki	Bioorg Med Chem Lett (2016) 26: 401-405 [PMID:26691758]
Carbonic anhydrase in Mycobacterium tuberculosis (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL6068] [UniProtKB: P9WPJ9]
ChEMBL	Inhibition of full length Mycobacterium tuberculosis H37Rv recombinant carbonic anhydrase 2 encoded by RV3588c by stopped flow CO2 hydration assay	B	6.14	pKi	717	nM	Ki	Bioorg Med Chem Lett (2009) 19: 6649-6654 [PMID:19846301]
Carbonic anhydrase in Stylophora pistillata (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL1649055] [UniProtKB: C0IX24]
ChEMBL	Inhibition of Stylophora pistillata carbonic anhydrase 2 by stopped-flow CO2 hydration assay	B	6.4	pKi	394	nM	Ki	Bioorg Med Chem Lett (2011) 21: 710-714 [PMID:21208801]
Carbonic anhydrase in Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL5337] [UniProtKB: Q5AJ71]
ChEMBL	Inhibition of Candida albicans recombinant Nce103 by stopped-flow CO2 hydration assay	B	5.96	pKi	1090	nM	Ki	Bioorg Med Chem (2009) 17: 4503-4509 [PMID:19450983]
ChEMBL	Inhibition of Candida albicans CaNce103 preincubated for 15 mins measured for 10 to 100 sec by stopped-flow method	B	5.96	pKi	1090	nM	Ki	J Med Chem (2012) 55: 3513-3520 [PMID:22424239]
Carbonic anhydrase in Candida glabrata CBS 138 (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL6185] [UniProtKB: Q6FTL6]
ChEMBL	Inhibition of recombinant full length Candida glabrata NCE103 expressed in Escherichia coli BL21 preincubated for 15 mins by stopped-flow CO2 hydrase assay	B	7.03	pKi	94	nM	Ki	Bioorg Med Chem Lett (2013) 23: 2647-2652 [PMID:23511020]
Carbonic anhydrase in Saccharomyces cerevisiae S288c (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL5931] [UniProtKB: P53615]
ChEMBL	Inhibition of Saccharomyces cerevisiae recombinant CA expressed in Escherichia coli by stopped-flow CO2 hydrase assay	B	6.88	pKi	133	nM	Ki	Bioorg Med Chem (2009) 17: 1158-1163 [PMID:19124253]
Carbonic anhydrase 1 in Helicobacter pylori (strain ATCC 700392 / 26695) (Campylobacterpylori) (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL4211] [UniProtKB: O24855]
ChEMBL	Inhibition of Helicobacter pylori recombinant CA	B	6.36	pKi	434	nM	Ki	Bioorg Med Chem Lett (2006) 16: 2182-2188 [PMID:16459077]
ChEMBL	Inhibition of Helicobacter pylori recombinant carbonic anhydrase by stopped-flow CO2 hydrase assay	B	6.38	pKi	413	nM	Ki	J Med Chem (2006) 49: 2117-2126 [PMID:16539401]
Carbonic anhydrase 15 in Mouse (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL5973] [UniProtKB: Q99N23]
ChEMBL	Inhibition of mouse recombinant carbonic anhydrase 15 by stopped flow CO2 hydrase assay	B	7.14	pKi	72	nM	Ki	J Med Chem (2009) 52: 646-654 [PMID:19193158]
Carbonic anhydrase 2 in Cryptococcus neoformans var. grubii (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL1697676] [UniProtKB: Q3I4V7]
ChEMBL	Inhibition of Cryptococcus neoformans Can2 preincubated for 15 mins measured for 10 to 100 sec by stopped-flow method	B	6.02	pKi	963	nM	Ki	J Med Chem (2012) 55: 3513-3520 [PMID:22424239]
Carbonic anhydrase, alpha family in Thiomicrospira crunogena (strain XCL-2) (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3621035] [UniProtKB: Q31FD6]
ChEMBL	Inhibition of recombinant Thiomicrospira crunogena XCL-2 carbonic anhydrase by stopped flow CO2 hydrase assay	B	6.56	pKi	273	nM	Ki	Bioorg Med Chem Lett (2016) 26: 401-405 [PMID:26691758]
carbonic anhydrase 1/Carbonic anhydrase I in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL261] [GtoPdb: 2597] [UniProtKB: P00915]
ChEMBL	Inhibition of human recombinant CA1 by stopped flow CO2 hydration assay	B	7.01	pKi	97	nM	Ki	J Med Chem (2009) 52: 4063-4067 [PMID:19438226]
ChEMBL	Inhibitory activity against human carbonic anhydrase I	B	7.51	pKi	31	nM	Ki	Bioorg Med Chem Lett (2004) 14: 2351-2356 [PMID:15081039]
ChEMBL	Inhibitory activity against Carbonic anhydrase I	B	7.51	pKi	31	nM	Ki	J Med Chem (2005) 48: 2121-2125 [PMID:15771455]
ChEMBL	Inhibitory activity against cytosolic human carbonic anhydrase I	B	7.51	pKi	31	nM	Ki	Bioorg Med Chem Lett (2005) 15: 579-584 [PMID:15664816]
ChEMBL	Inhibitory activity against human carbonic anhydrase I expressed in Escherichia coli BL21	B	7.51	pKi	31	nM	Ki	Bioorg Med Chem Lett (2004) 14: 5427-5433 [PMID:15454239]
ChEMBL	Binding affinity towards human cloned carbonic anhydrase I	B	7.51	pKi	31	nM	Ki	Bioorg Med Chem Lett (2004) 14: 5775-5780 [PMID:15501039]
ChEMBL	Inhibitory constant against human Carbonic anhydrase I	B	7.51	pKi	31	nM	Ki	Bioorg Med Chem Lett (2005) 15: 3102-3108 [PMID:15905091]
ChEMBL	Inhibition constant against human (cloned) isozyme (hCA I) by the CO2 hydration method	B	7.51	pKi	31	nM	Ki	J Med Chem (2005) 48: 4834-4841 [PMID:16033263]
ChEMBL	Inhibitory constant against human Carbonic anhydrase I	B	7.51	pKi	31	nM	Ki	Bioorg Med Chem Lett (2005) 15: 2359-2364 [PMID:15837325]
ChEMBL	Inhibition constant against human carbonic anhydrase I	B	7.51	pKi	31	nM	Ki	Bioorg Med Chem Lett (2005) 15: 3096-3101 [PMID:15908204]
ChEMBL	Inhibitory activity against human cloned Carbonic anhydrase I by the CO2 hydration method	B	7.51	pKi	31	nM	Ki	Bioorg Med Chem Lett (2005) 15: 4872-4876 [PMID:16165351]
ChEMBL	Inhibition of human recombinant carbonic anhydrase 1 by stopped-flow CO2 hydrase assay	B	7.51	pKi	31	nM	Ki	J Med Chem (2006) 49: 2117-2126 [PMID:16539401]
ChEMBL	Inhibition of human recombinant CA1	B	7.51	pKi	31	nM	Ki	Bioorg Med Chem Lett (2006) 16: 2182-2188 [PMID:16459077]
ChEMBL	Inhibition of human recombinant carbonic anhydrase 1 by stopped-flow CO2 hydrase assay	B	7.51	pKi	31	nM	Ki	J Med Chem (2006) 49: 5544-5551 [PMID:16942027]
ChEMBL	Inhibition of human cloned CA1 by CO2 hydration assay	B	7.51	pKi	31	nM	Ki	Bioorg Med Chem Lett (2006) 16: 4846-4851 [PMID:16809036]
ChEMBL	Inhibition of human cloned CA1 by CO2 hydration method	B	7.51	pKi	31	nM	Ki	J Med Chem (2006) 49: 6539-6548 [PMID:17064072]
ChEMBL	Inhibition of human recombinant cytosolic isozyme CA I by stopped-flow CO2 hydrase method	B	7.51	pKi	31	nM	Ki	J Med Chem (2007) 50: 381-388 [PMID:17228881]
ChEMBL	Inhibition of human recombinant isozyme CA1 by CO2 hydration method	B	7.51	pKi	31	nM	Ki	J Med Chem (2007) 50: 1651-1657 [PMID:17343373]
ChEMBL	Inhibition of human recombinant carbonic anhydrase 1 by CO2 hydration method	B	7.51	pKi	31	nM	Ki	Bioorg Med Chem (2007) 15: 2298-2311 [PMID:17276072]
ChEMBL	Inhibition of human recombinant carbonic anhydrase 1 by CO2 hydration stopped-flow assay	B	7.51	pKi	31	nM	Ki	Bioorg Med Chem Lett (2008) 18: 3475-3480 [PMID:18513964]
ChEMBL	Inhibition of human recombinant carbonic anhydrase 1 by stopped flow CO2 hydration method	B	7.51	pKi	31	nM	Ki	J Med Chem (2009) 52: 2226-2232 [PMID:19317447]
ChEMBL	Inhibition of human recombinant CA1 by stopped-flow CO2 hydrase assay	B	7.51	pKi	31	nM	Ki	Bioorg Med Chem (2009) 17: 1158-1163 [PMID:19124253]
ChEMBL	Inhibition of human recombinant carbonic anhydrase 1 by stopped flow CO2 hydrase assay	B	7.51	pKi	31	nM	Ki	J Med Chem (2009) 52: 646-654 [PMID:19193158]
ChEMBL	Inhibition of human recombinant carbonic anhydrase 1 by stopped flow CO2 hydration assay	B	7.51	pKi	31	nM	Ki	J Med Chem (2009) 52: 3116-3120 [PMID:19338333]
ChEMBL	Inhibition of full length human cytosolic carbonic anhydrase 1 preincubated for 15 mins by stop flow CO2 hydrase assay	B	7.51	pKi	31	nM	Ki	Bioorg Med Chem Lett (2016) 26: 4184-4190 [PMID:27485387]
ChEMBL	Inhibition of recombinant human carbonic anhydrase 1 assessed as reduction in CO2 hydration preincubated for 15 mins followed by CO2 addition measured for 10 to 100 sec by Line-Weaver Burk plot analysis	B	7.51	pKi	31	nM	Ki	Bioorg Med Chem Lett (2017) 27: 490-495 [PMID:28025002]
ChEMBL	Inhibition of human carbonic anhydrase-1 assessed as reduction in CO2 hydration preincubated for 15 mins followed by CO2 addition measured for 10 to 100 secs by stopped-flow assay	B	7.51	pKi	31	nM	Ki	Bioorg Med Chem (2017) 25: 3555-3561 [PMID:28511911]
ChEMBL	Inhibition of human recombinant carbonic anhydrase 1 by stopped-flow CO2 hydrase method	B	7.51	pKi	31	nM	Ki	Bioorg Med Chem (2009) 17: 4503-4509 [PMID:19450983]
ChEMBL	Inhibition of human recombinant CA1 by stopped-flow CO2 assay	B	7.51	pKi	31	nM	Ki	Bioorg Med Chem (2009) 17: 5054-5058 [PMID:19520577]
ChEMBL	Inhibition of human carbonic anhydrase 1	B	7.51	pKi	31	nM	Ki	Bioorg Med Chem Lett (2010) 20: 3623-3627 [PMID:20478708]
ChEMBL	Inhibition of human cloned carbonic anhydrase 1 preincubated for 15 mins by stopped flow CO2 hydration assay	B	7.51	pKi	31	nM	Ki	Eur J Med Chem (2010) 45: 2396-2404 [PMID:20202722]
ChEMBL	Inhibition of human cloned CA1 after 15 mins by stopped-flow CO2 hydration assay	B	7.51	pKi	31	nM	Ki	Eur J Med Chem (2010) 45: 3656-3661 [PMID:20554082]
ChEMBL	Inhibition of human recombinant CA1 by stopped-flow CO2 hydration assay	B	7.51	pKi	31	nM	Ki	Bioorg Med Chem Lett (2011) 21: 710-714 [PMID:21208801]
ChEMBL	Inhibition of human carbonic anhydrase I by spectrophotometry at pH 7.5	B	7.51	pKi	31	nM	Ki	Bioorg Med Chem (2011) 19: 1172-1178 [PMID:21251841]
ChEMBL	Inhibition of human recombinant carbonic anhydrase 1 at pH 7.5 by stopped flow CO2 hydration assay	B	7.51	pKi	31	nM	Ki	Bioorg Med Chem (2011) 19: 5023-5030 [PMID:21757360]
ChEMBL	Inhibition of human cloned carbonic anhydrase 1 preincubated for 15 mins by stopped flow CO2 hydration assay	B	7.51	pKi	31	nM	Ki	Eur J Med Chem (2011) 46: 4403-4410 [PMID:21820216]
ChEMBL	Inhibition of human recombinant carbonic anhydrase 1 after 15 mins by stopped flow CO2 hydration assay	B	7.51	pKi	31	nM	Ki	Bioorg Med Chem (2012) 20: 1403-1410 [PMID:22285172]
ChEMBL	Inhibition of human recombinant carbonic anhydrase 1 by stopped flow CO2 hydration assay	B	7.51	pKi	31	nM	Ki	J Med Chem (2013) 56: 1761-1771 [PMID:23391336]
ChEMBL	Inhibition of human recombinant carbonic anhydrase 1 preincubated for 15 mins by CO2 hydration stopped-flow assay	B	7.51	pKi	31	nM	Ki	Bioorg Med Chem (2013) 21: 1534-1538 [PMID:22883029]
ChEMBL	Inhibition of human cytosolic carbonic anhydrase 1 preincubated for 15 mins by stopped flow CO2 hydration assay	B	7.51	pKi	31	nM	Ki	Bioorg Med Chem (2013) 21: 5168-5174 [PMID:23867389]
ChEMBL	Inhibition of human cytosolic carbonic anhydrase 1 preincubated for 15 mins at room temperature followed by 72 hrs at 4 degC by stopped flow CO2 hydration assay	B	7.51	pKi	31	nM	Ki	Bioorg Med Chem (2013) 21: 5973-5982 [PMID:23965175]
ChEMBL	Inhibition of human CA1 cytosolic isoform after 15 mins by stopped-flow CO2 hydration assay	B	7.51	pKi	31	nM	Ki	Eur J Med Chem (2014) 71: 135-147 [PMID:24291567]
ChEMBL	Inhibition of human cytosolic carbonic anhydrase 1 by stopped-flow CO2 hydration assay	B	7.51	pKi	31	nM	Ki	Bioorg Med Chem (2014) 22: 1586-1595 [PMID:24513184]
ChEMBL	Inhibition of human carbonic anhydrase-1 by stopped-flow CO2 hydration assay	B	7.51	pKi	31	nM	Ki	Bioorg Med Chem (2014) 22: 2939-2946 [PMID:24792813]
ChEMBL	Inhibition of human cloned cytosolic carbonic anhydrase 1 preincubated for 15 mins by stopped flow CO2 hydration assay	B	7.51	pKi	31	nM	Ki	Eur J Med Chem (2014) 82: 47-55 [PMID:24871996]
ChEMBL	Inhibition of human recombinant Carbonic anhydrase 1 compound preincubated for 15 mins by stopped flow CO2 hydrase assay method	B	7.51	pKi	31	nM	Ki	Bioorg Med Chem (2014) 22: 4537-4543 [PMID:25129169]
ChEMBL	Inhibition of human recombinant carbonic anhydrase 1 by stopped-flow CO2 hydration assay	B	7.51	pKi	31	nM	Ki	Bioorg Med Chem (2015) 23: 526-531 [PMID:25533402]
ChEMBL	Inhibition of human recombinant carbonic anhydrase 1 by stopped flow CO2 hydrase assay	B	7.51	pKi	31	nM	Ki	Bioorg Med Chem (2015) 23: 1728-1734 [PMID:25773015]
ChEMBL	Inhibition of human carbonic anhydrase 1 pre-incubated for 15 mins by stopped-flow CO2 hydration assay	B	7.51	pKi	31	nM	Ki	Bioorg Med Chem (2015) 23: 2303-2309 [PMID:25882523]
ChEMBL	Inhibition of human CA1 incubated for 15 mins prior to testing by stopped flow CO2 hydrase assay	B	7.51	pKi	31	nM	Ki	Bioorg Med Chem Lett (2015) 25: 5485-5489 [PMID:26525863]
ChEMBL	Inhibition of recombinant human carbonic anhydrase-1 by stopped flow CO2 hydrase assay	B	7.51	pKi	31	nM	Ki	Bioorg Med Chem Lett (2016) 26: 401-405 [PMID:26691758]
ChEMBL	Inhibition of human carbonic anhydrase-1 using p-nitrophenyl acetate as substrate by esterase assay	B	7.51	pKi	31	nM	Ki	Bioorg Med Chem Lett (2016) 26: 1337-1341 [PMID:26804228]
ChEMBL	Inhibition of human Carbonic anhydrase1 using CO2 as substrate preincubated for 15 mins by stopped-flow CO2 hydration assay	B	7.51	pKi	31	nM	Ki	Bioorg Med Chem (2016) 24: 1115-1120 [PMID:26850377]
ChEMBL	Inhibition of human carbonic anhydrase 1 incubated for 15 mins by stopped-flow CO2 hydration assay	B	7.51	pKi	31	nM	Ki	Bioorg Med Chem Lett (2016) 26: 1821-1826 [PMID:26920803]
GtoPdb	-	-	7.51	pKi	31	nM	Ki	Bioorg Med Chem (2013) 21: 5973-82 [PMID:23965175]
ChEMBL	Inhibition constant evaluated for the inhibition of human CA I (Carbonic anhydrase I)	B	7.52	pKi	30	nM	Ki	J Med Chem (2004) 47: 2337-2347 [PMID:15084132]
ChEMBL	Inhibitory activity against human carbonic anhydrase I	B	7.52	pKi	30	nM	Ki	Bioorg Med Chem Lett (2004) 14: 869-873 [PMID:15012984]
ChEMBL	Inhibitory activity of compound against human carbonic anhydrase I	F	7.51	pIC50	31	nM	IC50	Bioorg Med Chem Lett (2004) 14: 337-341 [PMID:14698154]
carbonic anhydrase 2/Carbonic anhydrase II in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL205] [GtoPdb: 3092] [UniProtKB: P00918]
ChEMBL	Inhibition of human recombinant CA2 by stopped flow CO2 hydration assay	B	5.11	pKi	7840	nM	Ki	J Med Chem (2009) 52: 4063-4067 [PMID:19438226]
ChEMBL	Inhibitory activity against human carbonic anhydrase II	B	7.82	pKi	15	nM	Ki	Bioorg Med Chem Lett (2004) 14: 2351-2356 [PMID:15081039]
ChEMBL	Inhibition constant evaluated for the inhibition of human CA II (Carbonic anhydrase II)	B	7.82	pKi	15	nM	Ki	J Med Chem (2004) 47: 2337-2347 [PMID:15084132]
ChEMBL	Inhibitory activity against Carbonic anhydrase II	B	7.82	pKi	15	nM	Ki	J Med Chem (2005) 48: 2121-2125 [PMID:15771455]
ChEMBL	Inhibitory activity against cytosolic human carbonic anhydrase II	B	7.82	pKi	15	nM	Ki	Bioorg Med Chem Lett (2005) 15: 579-584 [PMID:15664816]
ChEMBL	Inhibitory activity against human carbonic anhydrase II expressed in Escherichia coli BL21	B	7.82	pKi	15	nM	Ki	Bioorg Med Chem Lett (2004) 14: 5427-5433 [PMID:15454239]
ChEMBL	Binding affinity towards human cloned carbonic anhydrase II	B	7.82	pKi	15	nM	Ki	Bioorg Med Chem Lett (2004) 14: 5775-5780 [PMID:15501039]
ChEMBL	Inhibitory constant against human Carbonic anhydrase II	B	7.82	pKi	15	nM	Ki	Bioorg Med Chem Lett (2005) 15: 3102-3108 [PMID:15905091]
ChEMBL	Inhibition constant against human (cloned) isozyme (hCA II) by CO2 hydration method	B	7.82	pKi	15	nM	Ki	J Med Chem (2005) 48: 4834-4841 [PMID:16033263]
ChEMBL	Inhibitory constant against human Carbonic anhydrase II	B	7.82	pKi	15	nM	Ki	Bioorg Med Chem Lett (2005) 15: 2359-2364 [PMID:15837325]
ChEMBL	Inhibition constant against human carbonic anhydrase II	B	7.82	pKi	15	nM	Ki	Bioorg Med Chem Lett (2005) 15: 3096-3101 [PMID:15908204]
ChEMBL	Inhibitory activity against human cloned Carbonic anhydrase II by the CO2 hydration method	B	7.82	pKi	15	nM	Ki	Bioorg Med Chem Lett (2005) 15: 4872-4876 [PMID:16165351]
ChEMBL	Inhibition of cloned human carbonic anhydrase II	B	7.82	pKi	15	nM	Ki	J Med Chem (2005) 48: 5721-5727 [PMID:16134940]
ChEMBL