benzquinamide [Ligand Id: 7124] activity data from GtoPdb and ChEMBL

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ChEMBL ligand: CHEMBL1201250 (Benzchinamide, Benzquinamide, Emete-con, NSC-108159, NSC-169193, NSC-64375, P-2647, Promecon, Quantril)
  • D2 receptor in Human [GtoPdb: 215] [UniProtKB: P14416]
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  • COX-2 in Human [GtoPdb: 1376] [UniProtKB: P35354]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
D2 receptor in Human [GtoPdb: 215] [UniProtKB: P14416]
GtoPdb - - 5.4 pKi 3964 nM Ki Proc Natl Acad Sci USA (2012) 109: 11178-83 [PMID:22711801]
COX-2 in Human [GtoPdb: 1376] [UniProtKB: P35354]
GtoPdb - - 8.32 pIC50 4.8 nM IC50 National Toxicology Program: Dept of Health and Human Services.. DrugMatrix

ChEMBL data shown on this page come from version 31:

Gaulton A, Hersey A, Nowotka M, Bento AP, Chambers J, Mendez D, Mutowo P, Atkinson F, Bellis LJ, Cibrián-Uhalte E, Davies M, Dedman N, Karlsson A, Magariños MP, Overington JP, Papadatos G, Smit I, Leach AR. (2017) 'The ChEMBL database in 2017.' Nucleic Acids Res., 45(D1). DOI: 10.1093/nar/gkw1074. [PMCID:5210557]