penicillamine [Ligand Id: 7264] activity data from GtoPdb and ChEMBL

Click here for a description of the charts and data table

Please tell us if you are using this feature and what you think!

ChEMBL ligand: CHEMBL1430 (Cuprimine, D-3-mercaptovaline, Depen, Dimethylcysteine, Distamine, D Mercaptovaline, D Penicillamine, NSC-758421, NSC-81549, Penicillamine, Trolovol)
  • Succinyl-diaminopimelate desuccinylase in Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) [ChEMBL: CHEMBL1075192] [UniProtKB: P44514]
There should be some charts here, you may need to enable JavaScript!
DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
Succinyl-diaminopimelate desuccinylase in Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL1075192] [UniProtKB: P44514]
ChEMBL Inhibition of Haemophilus influenzae recombinant DapE B 4.3 pIC50 50000 nM IC50 Bioorg Med Chem Lett (2009) 19: 6350-6352 [PMID:19822427]

ChEMBL data shown on this page come from version 32:

Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]