penicillamine [Ligand Id: 7264] activity data from GtoPdb and ChEMBL

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ChEMBL ligand: CHEMBL1430 (Cuprimine, Depen, D Penicillamine, Distamine, Trolovol, Penicillamine, Dimethylcysteine, NSC-81549, D Mercaptovaline)
  • Succinyl-diaminopimelate desuccinylase in Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) [ChEMBL: CHEMBL1075192] [UniProtKB: P44514]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
Succinyl-diaminopimelate desuccinylase in Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL1075192] [UniProtKB: P44514]
ChEMBL Inhibition of Haemophilus influenzae recombinant DapE B 4.3 pIC50 50000 nM IC50 Bioorg. Med. Chem. Lett. (2009) 19: 6350-6352 [PMID:19822427]

ChEMBL data shown on this page come from version 27:

Gaulton A, Hersey A, Nowotka M, Bento AP, Chambers J, Mendez D, Mutowo P, Atkinson F, Bellis LJ, CibriƔn-Uhalte E, Davies M, Dedman N, Karlsson A, MagariƱos MP, Overington JP, Papadatos G, Smit I, Leach AR. (2017) 'The ChEMBL database in 2017.' Nucleic Acids Res., 45(D1). DOI: 10.1093/nar/gkw1074. [PMCID:5210557]