ChEMBL ligand: CHEMBL122972 (2-Arachidonoylglycerol, 2-Arachidonoyl Glycerol, 2-Arachidonoyl-Glycerol, 2-Oarachidonoyl Glycerol)
Fatty acid amide hydrolase/Anandamide amidohydrolase in Human [ChEMBL: CHEMBL2243] [GtoPdb: 1400] [UniProtKB: O00519] There should be some charts here, you may need to enable JavaScript!
CB1 receptor/Cannabinoid CB1 receptor in Human [ChEMBL: CHEMBL218] [GtoPdb: 56] [UniProtKB: P21554] CB1 receptor/Cannabinoid CB1 receptor in Rat [ChEMBL: CHEMBL3571] [GtoPdb: 56] [UniProtKB: P20272] There should be some charts here, you may need to enable JavaScript!
CB2 receptor/Cannabinoid CB2 receptor in Human [ChEMBL: CHEMBL253] [GtoPdb: 57] [UniProtKB: P34972] CB2 receptor/Cannabinoid CB2 receptor in Rat [ChEMBL: CHEMBL2470] [GtoPdb: 57] [UniProtKB: Q9QZN9] There should be some charts here, you may need to enable JavaScript!
GPR55 in Human [GtoPdb: 109] [UniProtKB: Q9Y2T6] There should be some charts here, you may need to enable JavaScript!

DB	Assay description	Assay Type	Standard value	Standard parameter	Original value	Original units	Original parameter	Reference
Fatty acid amide hydrolase/Anandamide amidohydrolase in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2243] [GtoPdb: 1400] [UniProtKB: O00519]
ChEMBL	Inhibition of Fatty-acid amide hydrolase (FAAH) activity in human lymphoma U937 cell using [3H]AEA as substrate in the 0-25 uM conc	B	5.3	pKi	5000	nM	Ki	J Med Chem (2002) 45: 3709-3720 [PMID:12166944]
CB1 receptor/Cannabinoid CB1 receptor in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL218] [GtoPdb: 56] [UniProtKB: P21554]
ChEMBL	Binding affinity to CB1R (unknown origin)	B	6	pKi	1000	nM	Ki	J Med Chem (2017) 60: 4-46 [PMID:27766867]
ChEMBL	Displacement of [3H]-CP55940 from human CB1 receptor expressed in HEK-293-EBNA cell membranes after 90 mins by scintillation counting	B	6.32	pKi	480	nM	Ki	J Med Chem (2011) 54: 5265-5269 [PMID:21675776]
ChEMBL	Binding affinity to CB1 receptor (unknown origin)	B	6.33	pKi	472	nM	Ki	Bioorg Med Chem (2016) 24: 5291-5301 [PMID:27624523]
ChEMBL	Displacement of [3H]CP55940 from human CB1 receptor expressed in human HEK293 cells	B	6.33	pKi	470	nM	Ki	J Med Chem (2011) 54: 8278-8288 [PMID:22044209]
ChEMBL	Agonist activity at CB1 receptor expressed in NG108-15 cells assessed as increase in intracellular free calcium concentrations	F	7.64	pEC50	23	nM	EC50	Bioorg Med Chem (2007) 15: 854-867 [PMID:17110113]
CB1 receptor/Cannabinoid CB1 receptor in Rat (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3571] [GtoPdb: 56] [UniProtKB: P20272]
ChEMBL	Binding affinity to rat CB1 receptor	B	6.33	pKi	472	nM	Ki	J Med Chem (2013) 56: 8224-8256 [PMID:23865723]
ChEMBL	Displacement of [3H]CP55940 from CB1 receptor in Wistar rat brain incubated for 60 mins by radioactive filter binding assay	B	6.33	pKi	472	nM	Ki	Eur J Med Chem (2016) 112: 66-80 [PMID:26890113]
ChEMBL	Displacement of [3H]CP-55940 from rat forebrain membrane which expresses Cannabinoid receptor 1 in the presence of PMSF	B	7	pKi	100	nM	Ki	J Med Chem (2002) 45: 3709-3720 [PMID:12166944]
GtoPdb	-	-	7.2	pKi	-	-	-	Biochem Pharmacol (1995) 50: 83-90 [PMID:7605349]; Eur J Pharmacol (1998) 353: 23-31 [PMID:9721036]
ChEMBL	Potency at CB1 receptor in rat brain by [35S]GTP-gamma-S binding assay	F	6	pEC50	1000	nM	EC50	Bioorg Med Chem Lett (2006) 16: 2437-2440 [PMID:16466915]
CB2 receptor/Cannabinoid CB2 receptor in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL253] [GtoPdb: 57] [UniProtKB: P34972]
ChEMBL	Displacement of [3H]CP55940 from human CB2 receptor expressed in human HEK293 cells	B	5.85	pKi	1400	nM	Ki	J Med Chem (2011) 54: 8278-8288 [PMID:22044209]
ChEMBL	Binding affinity to human CB2 receptor	B	5.85	pKi	1400	nM	Ki	J Med Chem (2013) 56: 8224-8256 [PMID:23865723]
ChEMBL	Binding affinity to CB2 receptor (unknown origin)	B	5.85	pKi	1400	nM	Ki	Bioorg Med Chem (2016) 24: 5291-5301 [PMID:27624523]
ChEMBL	Displacement of [3H]-CP55940 from human CB2 receptor expressed in HEK-293-EBNA cell membranes after 90 mins by scintillation counting	B	5.89	pKi	1300	nM	Ki	J Med Chem (2011) 54: 5265-5269 [PMID:21675776]
GtoPdb	-	-	6.8	pKi	-	-	-	Biochem Pharmacol (1995) 50: 83-90 [PMID:7605349]; Eur J Pharmacol (1998) 353: 23-31 [PMID:9721036]
ChEMBL	Agonist activity at CB2 receptor expressed in HL60 cells assessed as increase in intracellular free calcium concentrations	F	7.77	pEC50	17	nM	EC50	Bioorg Med Chem (2007) 15: 854-867 [PMID:17110113]
CB2 receptor/Cannabinoid CB2 receptor in Rat (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2470] [GtoPdb: 57] [UniProtKB: Q9QZN9]
ChEMBL	Displacement of [3H]CP-55940 from rat forebrain membrane which expresses Cannabinoid receptor 2 in the presence of PMSF	B	7	pKi	100	nM	Ki	J Med Chem (2002) 45: 3709-3720 [PMID:12166944]
GPR55 in Human [GtoPdb: 109] [UniProtKB: Q9Y2T6]
GtoPdb	-	-	8.52	pEC50	3	nM	EC50	Br J Pharmacol (2007) 152: 1092-101 [PMID:17876302]

ChEMBL data shown on this page come from version 32:

Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]