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ChEMBL ligand: CHEMBL2103822 (BMS-214,778, BMS-214778, Hetlioz, Hetlioz lq, Tasimelteon, VEC-162) |
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DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
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MT1 receptor in Human [GtoPdb: 287] [UniProtKB: P48039] | ||||||||
GtoPdb | - | - | 9.5 | pKi | 0.3 | nM | Ki |
Tasimelteon Advisory Committee Meeting Briefing Materials.. FDA; Lancet (2009) 373: 482-91 [PMID:19054552] |
MT2 receptor in Human [GtoPdb: 288] [UniProtKB: P49286] | ||||||||
GtoPdb | - | - | 10.2 | pKi | 0.07 | nM | Ki |
Tasimelteon Advisory Committee Meeting Briefing Materials.. FDA; Lancet (2009) 373: 482-91 [PMID:19054552] |
ChEMBL data shown on this page come from version 34:
Zdrazil B, Felix E, Hunter F, Manners EJ, Blackshaw J, Corbett S, de Veij M, Ioannidis H, Lopez DM, Mosquera JF, Magarinos MP, Bosc N, Arcila R, Kizilören T, Gaulton A, Bento AP, Adasme MF, Monecke P, Landrum GA, Leach AR. (2024). The ChEMBL Database in 2023: a drug discovery platform spanning multiple bioactivity data types and time periods. Nucleic Acids Res., 52(D1). DOI: 10.1093/nar/gkad1004. [EPMCID:10767899] [PMID:37933841]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]