ulipristal acetate [Ligand Id: 7460] activity data from GtoPdb and ChEMBL

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ChEMBL ligand: CHEMBL260538 (Ella, Ulipristal acetate, VA2914, Ulipristal acetate, CDB-2914, Ellaone, Ulipristal acet, PGL-4001, RTI-3021-012, Esmya, VA-2914)
  • Progesterone receptor in Human [ChEMBL: CHEMBL208] [GtoPdb: 627] [UniProtKB: P06401]
  • This target only has 0 pki data point
  • 0
1 CHEMBL260538_lig_chart_1 Progesterone receptor Human
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
Progesterone receptor in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL208] [GtoPdb: 627] [UniProtKB: P06401]
ChEMBL Antagonist activity at human PRB expressed in CHO cells assessed as inhibition of Org 2058 induced-transactivation F 9.7 pIC50 0.2 nM IC50 Bioorg. Med. Chem. (2008) 16: 2753-2763 [PMID:18243712]
GtoPdb - - 9.7 pIC50 0.2 nM IC50 Bioorg Med Chem (2008) 16: 2753-63 [PMID:18243712]
GtoPdb - - 7 pEC50 >100 nM EC50 Bioorg Med Chem (2008) 16: 2753-63 [PMID:18243712]
ChEMBL Agonist activity at human PRB expressed in CHO cells F 7 pEC50 >100 nM EC50 Bioorg. Med. Chem. (2008) 16: 2753-2763 [PMID:18243712]

ChEMBL data shown on this page come from version 28:

Gaulton A, Hersey A, Nowotka M, Bento AP, Chambers J, Mendez D, Mutowo P, Atkinson F, Bellis LJ, CibriƔn-Uhalte E, Davies M, Dedman N, Karlsson A, MagariƱos MP, Overington JP, Papadatos G, Smit I, Leach AR. (2017) 'The ChEMBL database in 2017.' Nucleic Acids Res., 45(D1). DOI: 10.1093/nar/gkw1074. [PMCID:5210557]