levomepromazine [Ligand Id: 7603] activity data from GtoPdb and ChEMBL

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ChEMBL ligand: CHEMBL1764 (Levomepromazine, N05AA02, Tisercin, CL 36467, SK&F-5116, XP-03, CL-36467, CL 39743, Levoprome, NSC-226516, XP03, Methotrimeprazine, RP 7044, CL-39743, SK&F 5116, Nirvan, RP-7044)
  • Pleiotropic ABC efflux transporter of multiple drugs in Saccharomyces cerevisiae S288c [ChEMBL: CHEMBL1697658] [UniProtKB: P33302]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
Pleiotropic ABC efflux transporter of multiple drugs in Saccharomyces cerevisiae S288c (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL1697658] [UniProtKB: P33302]
ChEMBL Inhibition of Pdr5p-mediated rhodamine 6G transport in Saccharomyces cerevisiae MKPDR5h plasma membrane by spectrofluorometric assay B 5.02 pIC50 9600 nM IC50 Antimicrob. Agents Chemother. (2009) 53: 1516-1527 [PMID:19188399]

ChEMBL data shown on this page come from version 28:

Gaulton A, Hersey A, Nowotka M, Bento AP, Chambers J, Mendez D, Mutowo P, Atkinson F, Bellis LJ, CibriƔn-Uhalte E, Davies M, Dedman N, Karlsson A, MagariƱos MP, Overington JP, Papadatos G, Smit I, Leach AR. (2017) 'The ChEMBL database in 2017.' Nucleic Acids Res., 45(D1). DOI: 10.1093/nar/gkw1074. [PMCID:5210557]