fosaprepitant [Ligand Id: 7623] activity data from GtoPdb and ChEMBL

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ChEMBL ligand: CHEMBL1199324 (L-758298, Fosaprepitant, Ivemend)
  • NK1 receptor in Human [GtoPdb: 360] [UniProtKB: P25103]
  • This target only has 0 pki data point
1 CHEMBL1199324_lig_chart_1 NK1 receptor Human
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
NK1 receptor in Human [GtoPdb: 360] [UniProtKB: P25103]
GtoPdb - - 8.92 pIC50 1.2 nM IC50 J. Med. Chem. (2000) 43: 1234-41 [PMID:10737756]

ChEMBL data shown on this page come from version 27:

Gaulton A, Hersey A, Nowotka M, Bento AP, Chambers J, Mendez D, Mutowo P, Atkinson F, Bellis LJ, Cibrián-Uhalte E, Davies M, Dedman N, Karlsson A, Magariños MP, Overington JP, Papadatos G, Smit I, Leach AR. (2017) 'The ChEMBL database in 2017.' Nucleic Acids Res., 45(D1). DOI: 10.1093/nar/gkw1074. [PMCID:5210557]