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ChEMBL ligand: CHEMBL1946618 |
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DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
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δ receptor/Delta opioid receptor in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL236] [GtoPdb: 317] [UniProtKB: P41143] | ||||||||
GtoPdb | - | - | 9.52 | pKi | 0.3 | nM | Ki | AZD7268 δ‐Opioid receptor agonist.. MRC/AstraZeneca: Mechanisms of Disease Call |
ChEMBL | Displacement of radiolabeled iodinated deltorphin 2 from delta opioid receptor expressed in HEK293 cell membranes | B | 9.55 | pIC50 | 0.28 | nM | IC50 | Bioorg. Med. Chem. Lett. (2012) 22: 1174-1178 [PMID:22197137] |
μ receptor/Mu opioid receptor in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL233] [GtoPdb: 319] [UniProtKB: P35372] | ||||||||
ChEMBL | Displacement of radiolabeled FK33-824 from mu opioid receptor expressed in HEK293 cell membranes | B | 6.34 | pIC50 | 460 | nM | IC50 | Bioorg. Med. Chem. Lett. (2012) 22: 1174-1178 [PMID:22197137] |
ChEMBL data shown on this page come from version 28:
Gaulton A, Hersey A, Nowotka M, Bento AP, Chambers J, Mendez D, Mutowo P, Atkinson F, Bellis LJ, Cibrián-Uhalte E, Davies M, Dedman N, Karlsson A, Magariños MP, Overington JP, Papadatos G, Smit I, Leach AR. (2017) 'The ChEMBL database in 2017.' Nucleic Acids Res., 45(D1). DOI: 10.1093/nar/gkw1074. [PMCID:5210557]