ChEMBL ligand: CHEMBL3187723 (MEK162, MEK-162, Mektovi, Binimetinib, ARRY-162, NVP-MEK162, Mek-162, ARRY 438162, ARRY-438162)
mitogen-activated protein kinase kinase 1 in Human [GtoPdb: 2062] [UniProtKB: Q02750] This target only has 0 pki data point 0 1 CHEMBL3187723_lig_chart_1 mitogen-activated protein kinase kinase 1 Human There should be some charts here, you may need to enable JavaScript!
mitogen-activated protein kinase kinase 2 in Human [GtoPdb: 2063] [UniProtKB: P36507] This target only has 0 pki data point 0 2 CHEMBL3187723_lig_chart_2 mitogen-activated protein kinase kinase 2 Human There should be some charts here, you may need to enable JavaScript!

DB	Assay description	Assay Type	Standard value	Standard parameter	Original value	Original units	Original parameter	Reference
mitogen-activated protein kinase kinase 1 in Human [GtoPdb: 2062] [UniProtKB: Q02750]
GtoPdb	-	-	7.92	pIC50	12	nM	IC50	American College of Rheumatology 2006 Annual Scientific Meeting (2006) : Abstract 794
mitogen-activated protein kinase kinase 2 in Human [GtoPdb: 2063] [UniProtKB: P36507]
GtoPdb	-	-	7.92	pIC50	12	nM	IC50	American College of Rheumatology 2006 Annual Scientific Meeting (2006) : Abstract 794

ChEMBL data shown on this page come from version 28:

Gaulton A, Hersey A, Nowotka M, Bento AP, Chambers J, Mendez D, Mutowo P, Atkinson F, Bellis LJ, Cibrián-Uhalte E, Davies M, Dedman N, Karlsson A, Magariños MP, Overington JP, Papadatos G, Smit I, Leach AR. (2017) 'The ChEMBL database in 2017.' Nucleic Acids Res., 45(D1). DOI: 10.1093/nar/gkw1074. [PMCID:5210557]