refametinib [Ligand Id: 7942] activity data from GtoPdb

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  • mitogen-activated protein kinase kinase 1 in Human [GtoPdb: 2062] [UniProtKB: Q02750]
  • This target only has 0 pki data point
  • 0
1 _lig_chart_1 mitogen-activated protein kinase kinase 1 Human
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  • mitogen-activated protein kinase kinase 2 in Human [GtoPdb: 2063] [UniProtKB: P36507]
  • This target only has 0 pki data point
  • 0
2 _lig_chart_2 mitogen-activated protein kinase kinase 2 Human
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
mitogen-activated protein kinase kinase 1 in Human [GtoPdb: 2062] [UniProtKB: Q02750]
GtoPdb - - 7.72 pIC50 19 nM IC50 Cancer Res (2009) 69: 6839-47 [PMID:19706763]
mitogen-activated protein kinase kinase 2 in Human [GtoPdb: 2063] [UniProtKB: P36507]
GtoPdb - - 7.33 pIC50 47 nM IC50 Cancer Res (2009) 69: 6839-47 [PMID:19706763]

Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.