XL019 [Ligand Id: 7971] activity data from GtoPdb

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  • Janus kinase 1 in Human [GtoPdb: 2047] [UniProtKB: P23458]
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  • Janus kinase 2 in Human [GtoPdb: 2048] [UniProtKB: O60674]
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  • Janus kinase 3 in Human [GtoPdb: 2049] [UniProtKB: P52333]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
Janus kinase 1 in Human [GtoPdb: 2047] [UniProtKB: P23458]
GtoPdb - - 6.87 pIC50 134.3 nM IC50 Bioorg. Med. Chem. Lett. (2012) 22: 7653-8 [PMID:23127890]
Janus kinase 2 in Human [GtoPdb: 2048] [UniProtKB: O60674]
GtoPdb - - 8.66 pIC50 2.2 nM IC50 Bioorg. Med. Chem. Lett. (2012) 22: 7653-8 [PMID:23127890]
Janus kinase 3 in Human [GtoPdb: 2049] [UniProtKB: P52333]
GtoPdb - - 6.67 pIC50 214.2 nM IC50 Bioorg. Med. Chem. Lett. (2012) 22: 7653-8 [PMID:23127890]

Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.