ChEMBL ligand: CHEMBL2333365
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3/6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 in Human [ChEMBL: CHEMBL2331053] [GtoPdb: 2937] [UniProtKB: Q16875] There should be some charts here, you may need to enable JavaScript!
ALK receptor tyrosine kinase/ALK tyrosine kinase receptor in Human [ChEMBL: CHEMBL4247] [GtoPdb: 1839] [UniProtKB: Q9UM73] There should be some charts here, you may need to enable JavaScript!
protein kinase AMP-activated non-catalytic subunit beta 1/AMP-activated protein kinase, beta-1 subunit in Human [ChEMBL: CHEMBL3847] [GtoPdb: 1543] [UniProtKB: Q9Y478] There should be some charts here, you may need to enable JavaScript!
BR serine/threonine kinase 1/BR serine/threonine-protein kinase 1 in Human [ChEMBL: CHEMBL5650] [GtoPdb: 1946] [UniProtKB: Q8TDC3] There should be some charts here, you may need to enable JavaScript!
calcium/calmodulin dependent protein kinase I/CaM kinase I alpha in Human [ChEMBL: CHEMBL2493] [GtoPdb: 1952] [UniProtKB: Q14012] There should be some charts here, you may need to enable JavaScript!
calcium/calmodulin dependent protein kinase IV/CaM kinase IV in Human [ChEMBL: CHEMBL2494] [GtoPdb: 1955] [UniProtKB: Q16566] There should be some charts here, you may need to enable JavaScript!
casein kinase 1 delta/Casein kinase I delta in Human [ChEMBL: CHEMBL2828] [GtoPdb: 1997] [UniProtKB: P48730] There should be some charts here, you may need to enable JavaScript!
casein kinase 2, alpha prime polypeptide subunit/casein kinase 2, beta polypeptide subunit/casein kinase 2, alpha 1 polypeptide subunit/Casein kinase II in Human [ChEMBL: CHEMBL2095191] [GtoPdb: 1550, 1551, 1549] [UniProtKB: P19784, P67870, P68400] There should be some charts here, you may need to enable JavaScript!
cyclin dependent kinase 3/CDK3/cyclin E in Human [ChEMBL: CHEMBL2111444] [GtoPdb: 1975] [UniProtKB: O96020, P24864, Q00526] There should be some charts here, you may need to enable JavaScript!
cell division cycle 7/Cell division cycle 7-related protein kinase in Human [ChEMBL: CHEMBL5443] [GtoPdb: 1960] [UniProtKB: O00311] There should be some charts here, you may need to enable JavaScript!
Protein kinase G (PKG) 1/cGMP-dependent protein kinase 1 beta in Human [ChEMBL: CHEMBL4273] [GtoPdb: 1492] [UniProtKB: Q13976] There should be some charts here, you may need to enable JavaScript!
mitogen-activated protein kinase 8/c-Jun N-terminal kinase 1 in Human [ChEMBL: CHEMBL2276] [GtoPdb: 1496] [UniProtKB: P45983] There should be some charts here, you may need to enable JavaScript!
mitogen-activated protein kinase 10/c-Jun N-terminal kinase 3 in Human [ChEMBL: CHEMBL2637] [GtoPdb: 1498] [UniProtKB: P53779] There should be some charts here, you may need to enable JavaScript!
cyclin dependent kinase 5/Cyclin-dependent kinase 5/CDK5 activator 1 in Human [ChEMBL: CHEMBL1907600] [GtoPdb: 1977] [UniProtKB: Q00535, Q15078] There should be some charts here, you may need to enable JavaScript!
death associated protein kinase 2/Death-associated protein kinase 2 in Human [ChEMBL: CHEMBL3123] [GtoPdb: 2003] [UniProtKB: Q9UIK4] There should be some charts here, you may need to enable JavaScript!
death associated protein kinase 3/Death-associated protein kinase 3 in Human [ChEMBL: CHEMBL2468] [GtoPdb: 2004] [UniProtKB: O43293] There should be some charts here, you may need to enable JavaScript!
discoidin domain receptor tyrosine kinase 2/Discoidin domain-containing receptor 2 in Human [ChEMBL: CHEMBL5122] [GtoPdb: 1844] [UniProtKB: Q16832] There should be some charts here, you may need to enable JavaScript!
protein kinase, DNA-activated, catalytic subunit/DNA-dependent protein kinase in Human [ChEMBL: CHEMBL3142] [GtoPdb: 2800] [UniProtKB: P78527] There should be some charts here, you may need to enable JavaScript!
mitogen-activated protein kinase kinase 1/Dual specificity mitogen-activated protein kinase kinase 1 in Human [ChEMBL: CHEMBL3587] [GtoPdb: 2062] [UniProtKB: Q02750] There should be some charts here, you may need to enable JavaScript!
mitogen-activated protein kinase kinase 4/Dual specificity mitogen-activated protein kinase kinase 4 in Human [ChEMBL: CHEMBL2897] [GtoPdb: 2065] [UniProtKB: P45985] There should be some charts here, you may need to enable JavaScript!
mitogen-activated protein kinase kinase 6/Dual specificity mitogen-activated protein kinase kinase 6 in Human [ChEMBL: CHEMBL2171] [GtoPdb: 2067] [UniProtKB: P52564] There should be some charts here, you may need to enable JavaScript!
mitogen-activated protein kinase kinase 7/Dual specificity mitogen-activated protein kinase kinase 7 in Human [ChEMBL: CHEMBL3530] [GtoPdb: 2068] [UniProtKB: O14733] There should be some charts here, you may need to enable JavaScript!
CDC like kinase 2/Dual specificity protein kinase CLK2 in Human [ChEMBL: CHEMBL4225] [GtoPdb: 1991] [UniProtKB: P49760] There should be some charts here, you may need to enable JavaScript!
dual specificity tyrosine phosphorylation regulated kinase 2/Dual-specificity tyrosine-phosphorylation regulated kinase 2 in Human [ChEMBL: CHEMBL4376] [GtoPdb: 2011] [UniProtKB: Q92630] There should be some charts here, you may need to enable JavaScript!
EPH receptor A2/Ephrin type-A receptor 2 in Human [ChEMBL: CHEMBL2068] [GtoPdb: 1822] [UniProtKB: P29317] There should be some charts here, you may need to enable JavaScript!
EPH receptor B1/Ephrin type-B receptor 1 in Human [ChEMBL: CHEMBL5072] [GtoPdb: 1830] [UniProtKB: P54762] There should be some charts here, you may need to enable JavaScript!
epidermal growth factor receptor/Epidermal growth factor receptor erbB1 in Human [ChEMBL: CHEMBL203] [GtoPdb: 1797] [UniProtKB: P00533] There should be some charts here, you may need to enable JavaScript!
fibroblast growth factor receptor 1/Fibroblast growth factor receptor 1 in Human [ChEMBL: CHEMBL3650] [GtoPdb: 1808] [UniProtKB: P11362] There should be some charts here, you may need to enable JavaScript!
fibroblast growth factor receptor 2/Fibroblast growth factor receptor 2 in Human [ChEMBL: CHEMBL4142] [GtoPdb: 1809] [UniProtKB: P21802] There should be some charts here, you may need to enable JavaScript!
fibroblast growth factor receptor 3/Fibroblast growth factor receptor 3 in Human [ChEMBL: CHEMBL2742] [GtoPdb: 1810] [UniProtKB: P22607] There should be some charts here, you may need to enable JavaScript!
fibroblast growth factor receptor 4/Fibroblast growth factor receptor 4 in Human [ChEMBL: CHEMBL3973] [GtoPdb: 1811] [UniProtKB: P22455] There should be some charts here, you may need to enable JavaScript!
protein tyrosine kinase 2/Focal adhesion kinase 1 in Human [ChEMBL: CHEMBL2695] [GtoPdb: 2180] [UniProtKB: Q05397] There should be some charts here, you may need to enable JavaScript!
glycogen synthase kinase 3 alpha/Glycogen synthase kinase-3 alpha in Human [ChEMBL: CHEMBL2850] [GtoPdb: 2029] [UniProtKB: P49840] There should be some charts here, you may need to enable JavaScript!
glycogen synthase kinase 3 beta/Glycogen synthase kinase-3 beta in Human [ChEMBL: CHEMBL262] [GtoPdb: 2030] [UniProtKB: P49841] There should be some charts here, you may need to enable JavaScript!
G protein-coupled receptor kinase 5 in Human [ChEMBL: CHEMBL5678] [GtoPdb: 1469] [UniProtKB: P34947] There should be some charts here, you may need to enable JavaScript!
heat shock protein 90 alpha family class B member 1/Heat shock protein HSP 90-beta in Human [ChEMBL: CHEMBL4303] [GtoPdb: 2907] [UniProtKB: P08238] There should be some charts here, you may need to enable JavaScript!
MET proto-oncogene, receptor tyrosine kinase/Hepatocyte growth factor receptor in Human [ChEMBL: CHEMBL3717] [GtoPdb: 1815] [UniProtKB: P08581] There should be some charts here, you may need to enable JavaScript!
homeodomain interacting protein kinase 2/Homeodomain-interacting protein kinase 2 in Human [ChEMBL: CHEMBL4576] [GtoPdb: 2034] [UniProtKB: Q9H2X6] There should be some charts here, you may need to enable JavaScript!
component of inhibitor of nuclear factor kappa B kinase complex/Inhibitor of nuclear factor kappa B kinase alpha subunit in Human [ChEMBL: CHEMBL3476] [GtoPdb: 1989] [UniProtKB: O15111] There should be some charts here, you may need to enable JavaScript!
inhibitor of nuclear factor kappa B kinase subunit beta/Inhibitor of nuclear factor kappa B kinase beta subunit in Human [ChEMBL: CHEMBL1991] [GtoPdb: 2039] [UniProtKB: O14920] There should be some charts here, you may need to enable JavaScript!
Insulin-like growth factor I receptor in Human [ChEMBL: CHEMBL1957] [GtoPdb: 1801] [UniProtKB: P08069] There should be some charts here, you may need to enable JavaScript!
interleukin 1 receptor associated kinase 1/Interleukin-1 receptor-associated kinase 1 in Human [ChEMBL: CHEMBL3357] [GtoPdb: 2042] [UniProtKB: P51617] There should be some charts here, you may need to enable JavaScript!
LIM domain kinase 1 in Human [ChEMBL: CHEMBL3836] [GtoPdb: 2054] [UniProtKB: P53667] There should be some charts here, you may need to enable JavaScript!
MAPK activated protein kinase 2/MAP kinase-activated protein kinase 2 in Human [ChEMBL: CHEMBL2208] [GtoPdb: 2094] [UniProtKB: P49137] There should be some charts here, you may need to enable JavaScript!
MAPK activated protein kinase 3/MAP kinase-activated protein kinase 3 in Human [ChEMBL: CHEMBL4670] [GtoPdb: 2095] [UniProtKB: Q16644] There should be some charts here, you may need to enable JavaScript!
MAPK activated protein kinase 5/MAP kinase-activated protein kinase 5 in Human [ChEMBL: CHEMBL3094] [GtoPdb: 2096] [UniProtKB: Q8IW41] There should be some charts here, you may need to enable JavaScript!
mitogen-activated protein kinase 1/MAP kinase ERK2 in Human [ChEMBL: CHEMBL4040] [GtoPdb: 1495] [UniProtKB: P28482] There should be some charts here, you may need to enable JavaScript!
MAPK interacting serine/threonine kinase 2/MAP kinase signal-integrating kinase 2 in Human [ChEMBL: CHEMBL4204] [GtoPdb: 2105] [UniProtKB: Q9HBH9] There should be some charts here, you may need to enable JavaScript!
misshapen like kinase 1/Misshapen-like kinase 1 in Human [ChEMBL: CHEMBL5518] [GtoPdb: 2103] [UniProtKB: Q8N4C8] There should be some charts here, you may need to enable JavaScript!
mitogen-activated protein kinase kinase kinase 5/Mitogen-activated protein kinase kinase kinase 5 in Human [ChEMBL: CHEMBL5285] [GtoPdb: 2080] [UniProtKB: Q99683] There should be some charts here, you may need to enable JavaScript!
mitogen-activated protein kinase kinase kinase 9/Mitogen-activated protein kinase kinase kinase 9 in Human [ChEMBL: CHEMBL2872] [GtoPdb: 2084] [UniProtKB: P80192] There should be some charts here, you may need to enable JavaScript!
mitogen-activated protein kinase kinase kinase kinase 2/Mitogen-activated protein kinase kinase kinase kinase 2 in Human [ChEMBL: CHEMBL5330] [GtoPdb: 2086] [UniProtKB: Q12851] There should be some charts here, you may need to enable JavaScript!
muscle associated receptor tyrosine kinase/Muscle, skeletal receptor tyrosine protein kinase in Human [ChEMBL: CHEMBL5684] [GtoPdb: 1847] [UniProtKB: O15146] There should be some charts here, you may need to enable JavaScript!
Testicular receptor 4/Nuclear receptor subfamily 2 group C member 2 in Human [ChEMBL: CHEMBL5716] [GtoPdb: 614] [UniProtKB: P49116] There should be some charts here, you may need to enable JavaScript!
PAS domain containing serine/threonine kinase/PAS domain-containing serine/threonine-protein kinase in Human [ChEMBL: CHEMBL6054] [GtoPdb: 2139] [UniProtKB: Q96RG2] There should be some charts here, you may need to enable JavaScript!
phosphatidylinositol 3-kinase catalytic subunit type 3/Phosphatidylinositol 3-kinase catalytic subunit type 3 in Human [ChEMBL: CHEMBL1075165] [GtoPdb: 2152] [UniProtKB: Q8NEB9] There should be some charts here, you may need to enable JavaScript!
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/PI3-kinase p110-alpha subunit in Human [ChEMBL: CHEMBL4005] [GtoPdb: 2153] [UniProtKB: P42336] There should be some charts here, you may need to enable JavaScript!
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta/PI3-kinase p110-beta subunit in Human [ChEMBL: CHEMBL3145] [GtoPdb: 2154] [UniProtKB: P42338] There should be some charts here, you may need to enable JavaScript!
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta/PI3-kinase p110-delta subunit in Human [ChEMBL: CHEMBL3130] [GtoPdb: 2155] [UniProtKB: O00329] There should be some charts here, you may need to enable JavaScript!
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma/PI3-kinase p110-gamma subunit in Human [ChEMBL: CHEMBL3267] [GtoPdb: 2156] [UniProtKB: P48736] There should be some charts here, you may need to enable JavaScript!
platelet derived growth factor receptor beta/Platelet-derived growth factor receptor beta in Human [ChEMBL: CHEMBL1913] [GtoPdb: 1804] [UniProtKB: P09619] There should be some charts here, you may need to enable JavaScript!
protein kinase C alpha/Protein kinase C alpha in Human [ChEMBL: CHEMBL299] [GtoPdb: 1482] [UniProtKB: P17252] There should be some charts here, you may need to enable JavaScript!
protein kinase C beta/Protein kinase C beta in Human [ChEMBL: CHEMBL3045] [GtoPdb: 1483] [UniProtKB: P05771] There should be some charts here, you may need to enable JavaScript!
protein kinase C delta/Protein kinase C delta in Human [ChEMBL: CHEMBL2996] [GtoPdb: 1485] [UniProtKB: Q05655] There should be some charts here, you may need to enable JavaScript!
protein kinase C epsilon/Protein kinase C epsilon in Human [ChEMBL: CHEMBL3582] [GtoPdb: 1486] [UniProtKB: Q02156] There should be some charts here, you may need to enable JavaScript!
protein kinase C eta/Protein kinase C eta in Human [ChEMBL: CHEMBL3616] [GtoPdb: 1487] [UniProtKB: P24723] There should be some charts here, you may need to enable JavaScript!
protein kinase C gamma/Protein kinase C gamma in Human [ChEMBL: CHEMBL2938] [GtoPdb: 1484] [UniProtKB: P05129] There should be some charts here, you may need to enable JavaScript!
protein kinase C iota/Protein kinase C iota in Human [ChEMBL: CHEMBL2598] [GtoPdb: 1490] [UniProtKB: P41743] There should be some charts here, you may need to enable JavaScript!
protein kinase D1/Protein kinase C mu in Human [ChEMBL: CHEMBL3863] [GtoPdb: 1489] [UniProtKB: Q15139] There should be some charts here, you may need to enable JavaScript!
protein kinase C theta/Protein kinase C theta in Human [ChEMBL: CHEMBL3920] [GtoPdb: 1488] [UniProtKB: Q04759] There should be some charts here, you may need to enable JavaScript!
protein kinase C zeta/Protein kinase C zeta in Human [ChEMBL: CHEMBL3438] [GtoPdb: 1491] [UniProtKB: Q05513] There should be some charts here, you may need to enable JavaScript!
protein kinase N2/Protein kinase N2 in Human [ChEMBL: CHEMBL3032] [GtoPdb: 1521] [UniProtKB: Q16513] There should be some charts here, you may need to enable JavaScript!
protein tyrosine kinase 2 beta/Protein tyrosine kinase 2 beta in Human [ChEMBL: CHEMBL5469] [GtoPdb: 2181] [UniProtKB: Q14289] There should be some charts here, you may need to enable JavaScript!
MER proto-oncogene, tyrosine kinase/Proto-oncogene tyrosine-protein kinase MER in Human [ChEMBL: CHEMBL5331] [GtoPdb: 1837] [UniProtKB: Q12866] There should be some charts here, you may need to enable JavaScript!
c-ros oncogene 1, receptor tyrosine kinase/Proto-oncogene tyrosine-protein kinase ROS in Human [ChEMBL: CHEMBL5568] [GtoPdb: 1840] [UniProtKB: P08922] There should be some charts here, you may need to enable JavaScript!
pyruvate dehydrogenase kinase 1/Pyruvate dehydrogenase kinase isoform 1 in Human [ChEMBL: CHEMBL4766] [GtoPdb: 2915] [UniProtKB: Q15118] There should be some charts here, you may need to enable JavaScript!
erb-b2 receptor tyrosine kinase 2/Receptor protein-tyrosine kinase erbB-2 in Human [ChEMBL: CHEMBL1824] [GtoPdb: 2019] [UniProtKB: P04626] There should be some charts here, you may need to enable JavaScript!
Rho associated coiled-coil containing protein kinase 1/Rho-associated protein kinase 1 in Human [ChEMBL: CHEMBL3231] [GtoPdb: 1503] [UniProtKB: Q13464] There should be some charts here, you may need to enable JavaScript!
Rho associated coiled-coil containing protein kinase 2/Rho-associated protein kinase 2 in Human [ChEMBL: CHEMBL2973] [GtoPdb: 1504] [UniProtKB: O75116] There should be some charts here, you may need to enable JavaScript!
ribosomal protein S6 kinase B1/Ribosomal protein S6 kinase 1 in Human [ChEMBL: CHEMBL4501] [GtoPdb: 1525] [UniProtKB: P23443] There should be some charts here, you may need to enable JavaScript!
ribosomal protein S6 kinase A1/Ribosomal protein S6 kinase alpha 1 in Human [ChEMBL: CHEMBL2553] [GtoPdb: 1527] [UniProtKB: Q15418] There should be some charts here, you may need to enable JavaScript!
ribosomal protein S6 kinase A2/Ribosomal protein S6 kinase alpha 2 in Human [ChEMBL: CHEMBL3906] [GtoPdb: 1529] [UniProtKB: Q15349] There should be some charts here, you may need to enable JavaScript!
ribosomal protein S6 kinase A3/Ribosomal protein S6 kinase alpha 3 in Human [ChEMBL: CHEMBL2345] [GtoPdb: 1528] [UniProtKB: P51812] There should be some charts here, you may need to enable JavaScript!
ribosomal protein S6 kinase A5/Ribosomal protein S6 kinase alpha 5 in Human [ChEMBL: CHEMBL4237] [GtoPdb: 1523] [UniProtKB: O75582] There should be some charts here, you may need to enable JavaScript!
ribosomal protein S6 kinase A6/Ribosomal protein S6 kinase alpha 6 in Human [ChEMBL: CHEMBL4924] [GtoPdb: 1530] [UniProtKB: Q9UK32] There should be some charts here, you may need to enable JavaScript!
serine/threonine kinase 10/Serine/threonine-protein kinase 10 in Human [ChEMBL: CHEMBL3981] [GtoPdb: 2211] [UniProtKB: O94804] There should be some charts here, you may need to enable JavaScript!
serine/threonine kinase 11/Serine/threonine-protein kinase 11 in Human [ChEMBL: CHEMBL5606] [GtoPdb: 2212] [UniProtKB: Q15831] There should be some charts here, you may need to enable JavaScript!
serine/threonine kinase 33/Serine/threonine-protein kinase 33 in Human [ChEMBL: CHEMBL6005] [GtoPdb: 2221] [UniProtKB: Q9BYT3] There should be some charts here, you may need to enable JavaScript!
AKT serine/threonine kinase 1/Serine/threonine-protein kinase AKT in Human [ChEMBL: CHEMBL4282] [GtoPdb: 1479] [UniProtKB: P31749] There should be some charts here, you may need to enable JavaScript!
AKT serine/threonine kinase 2/Serine/threonine-protein kinase AKT2 in Human [ChEMBL: CHEMBL2431] [GtoPdb: 1480] [UniProtKB: P31751] There should be some charts here, you may need to enable JavaScript!
AKT serine/threonine kinase 3/Serine/threonine-protein kinase AKT3 in Human [ChEMBL: CHEMBL4816] [GtoPdb: 2286] [UniProtKB: Q9Y243] There should be some charts here, you may need to enable JavaScript!
aurora kinase A/Serine/threonine-protein kinase Aurora-A in Human [ChEMBL: CHEMBL4722] [GtoPdb: 1936] [UniProtKB: O14965] There should be some charts here, you may need to enable JavaScript!
checkpoint kinase 1/Serine/threonine-protein kinase Chk1 in Human [ChEMBL: CHEMBL4630] [GtoPdb: 1987] [UniProtKB: O14757] There should be some charts here, you may need to enable JavaScript!
checkpoint kinase 2/Serine/threonine-protein kinase Chk2 in Human [ChEMBL: CHEMBL2527] [GtoPdb: 1988] [UniProtKB: O96017] There should be some charts here, you may need to enable JavaScript!
protein kinase D2/Serine/threonine-protein kinase D2 in Human [ChEMBL: CHEMBL4900] [GtoPdb: 2173] [UniProtKB: Q9BZL6] There should be some charts here, you may need to enable JavaScript!
histone H3 associated protein kinase/Serine/threonine-protein kinase haspin in Human [ChEMBL: CHEMBL1075163] [GtoPdb: 2028] [UniProtKB: Q8TF76] There should be some charts here, you may need to enable JavaScript!
microtubule affinity regulating kinase 1/Serine/threonine-protein kinase MARK1 in Human [ChEMBL: CHEMBL5940] [GtoPdb: 2097] [UniProtKB: Q9P0L2] There should be some charts here, you may need to enable JavaScript!
serine/threonine kinase 4/Serine/threonine-protein kinase MST1 in Human [ChEMBL: CHEMBL4598] [GtoPdb: 2225] [UniProtKB: Q13043] There should be some charts here, you may need to enable JavaScript!
NIMA related kinase 2/Serine/threonine-protein kinase NEK2 in Human [ChEMBL: CHEMBL3835] [GtoPdb: 2117] [UniProtKB: P51955] There should be some charts here, you may need to enable JavaScript!
NIMA related kinase 7/Serine/threonine-protein kinase NEK7 in Human [ChEMBL: CHEMBL4849] [GtoPdb: 2122] [UniProtKB: Q8TDX7] There should be some charts here, you may need to enable JavaScript!
nemo like kinase/Serine/threonine protein kinase NLK in Human [ChEMBL: CHEMBL5364] [GtoPdb: 2125] [UniProtKB: Q9UBE8] There should be some charts here, you may need to enable JavaScript!
p21 (RAC1) activated kinase 3/Serine/threonine-protein kinase PAK 3 in Human [ChEMBL: CHEMBL2999] [GtoPdb: 2135] [UniProtKB: O75914] There should be some charts here, you may need to enable JavaScript!
p21 (RAC1) activated kinase 6/Serine/threonine-protein kinase PAK6 in Human [ChEMBL: CHEMBL4311] [GtoPdb: 2137] [UniProtKB: Q9NQU5] There should be some charts here, you may need to enable JavaScript!
Pim-1 proto-oncogene, serine/threonine kinase/Serine/threonine-protein kinase PIM1 in Human [ChEMBL: CHEMBL2147] [GtoPdb: 2158] [UniProtKB: P11309] There should be some charts here, you may need to enable JavaScript!
polo like kinase 1/Serine/threonine-protein kinase PLK1 in Human [ChEMBL: CHEMBL3024] [GtoPdb: 2168] [UniProtKB: P53350] There should be some charts here, you may need to enable JavaScript!
polo like kinase 3/Serine/threonine-protein kinase PLK3 in Human [ChEMBL: CHEMBL4897] [GtoPdb: 2170] [UniProtKB: Q9H4B4] There should be some charts here, you may need to enable JavaScript!
Raf-1 proto-oncogene, serine/threonine kinase/Serine/threonine-protein kinase RAF in Human [ChEMBL: CHEMBL1906] [GtoPdb: 2184] [UniProtKB: P04049] There should be some charts here, you may need to enable JavaScript!
receptor interacting serine/threonine kinase 2/Serine/threonine-protein kinase RIPK2 in Human [ChEMBL: CHEMBL5014] [GtoPdb: 2190] [UniProtKB: O43353] There should be some charts here, you may need to enable JavaScript!
serum/glucocorticoid regulated kinase 1/Serine/threonine-protein kinase Sgk1 in Human [ChEMBL: CHEMBL2343] [GtoPdb: 1534] [UniProtKB: O00141] There should be some charts here, you may need to enable JavaScript!
serum/glucocorticoid regulated kinase 2/Serine/threonine-protein kinase Sgk2 in Human [ChEMBL: CHEMBL5794] [GtoPdb: 1535] [UniProtKB: Q9HBY8] There should be some charts here, you may need to enable JavaScript!
serum/glucocorticoid regulated kinase family member 3/Serine/threonine-protein kinase Sgk3 in Human [ChEMBL: CHEMBL6186] [GtoPdb: 1536] [UniProtKB: Q96BR1] There should be some charts here, you may need to enable JavaScript!
SRSF protein kinase 3/Serine/threonine-protein kinase SRPK3 in Human [ChEMBL: CHEMBL5415] [GtoPdb: 2210] [UniProtKB: Q9UPE1] There should be some charts here, you may need to enable JavaScript!
TAO kinase 1/Serine/threonine-protein kinase TAO1 in Human [ChEMBL: CHEMBL5261] [GtoPdb: 2233] [UniProtKB: Q7L7X3] There should be some charts here, you may need to enable JavaScript!
TANK binding kinase 1/Serine/threonine-protein kinase TBK1 in Human [ChEMBL: CHEMBL5408] [GtoPdb: 2237] [UniProtKB: Q9UHD2] There should be some charts here, you may need to enable JavaScript!
unc-51 like autophagy activating kinase 2/Serine/threonine-protein kinase ULK2 in Human [ChEMBL: CHEMBL5435] [GtoPdb: 2272] [UniProtKB: Q8IYT8] There should be some charts here, you may need to enable JavaScript!
VRK serine/threonine kinase 2/Serine/threonine-protein kinase VRK2 in Human [ChEMBL: CHEMBL1649059] [GtoPdb: 2276] [UniProtKB: Q86Y07] There should be some charts here, you may need to enable JavaScript!
WNK lysine deficient protein kinase 2/Serine/threonine-protein kinase WNK2 in Human [ChEMBL: CHEMBL5639] [GtoPdb: 2281] [UniProtKB: Q9Y3S1] There should be some charts here, you may need to enable JavaScript!
KIT proto-oncogene, receptor tyrosine kinase/Stem cell growth factor receptor in Human [ChEMBL: CHEMBL1936] [GtoPdb: 1805] [UniProtKB: P10721] There should be some charts here, you may need to enable JavaScript!
testis specific serine kinase 1B/Testis-specific serine/threonine-protein kinase 1 in Human [ChEMBL: CHEMBL6003] [GtoPdb: 2257] [UniProtKB: Q9BXA7] There should be some charts here, you may need to enable JavaScript!
tyrosine kinase non receptor 2/Tyrosine kinase non-receptor protein 2 in Human [ChEMBL: CHEMBL4599] [GtoPdb: 2246] [UniProtKB: Q07912] There should be some charts here, you may need to enable JavaScript!
ABL proto-oncogene 1, non-receptor tyrosine kinase/Tyrosine-protein kinase ABL in Human [ChEMBL: CHEMBL1862] [GtoPdb: 1923] [UniProtKB: P00519] There should be some charts here, you may need to enable JavaScript!
ABL proto-oncogene 2, non-receptor tyrosine kinase/Tyrosine-protein kinase ABL2 in Human [ChEMBL: CHEMBL4014] [GtoPdb: 1924] [UniProtKB: P42684] There should be some charts here, you may need to enable JavaScript!
BLK proto-oncogene, Src family tyrosine kinase/Tyrosine-protein kinase BLK in Human [ChEMBL: CHEMBL2250] [GtoPdb: 1940] [UniProtKB: P51451] There should be some charts here, you may need to enable JavaScript!
protein tyrosine kinase 6/Tyrosine-protein kinase BRK in Human [ChEMBL: CHEMBL4601] [GtoPdb: 2182] [UniProtKB: Q13882] There should be some charts here, you may need to enable JavaScript!
C-terminal Src kinase/Tyrosine-protein kinase CSK in Human [ChEMBL: CHEMBL2634] [GtoPdb: 1994] [UniProtKB: P41240] There should be some charts here, you may need to enable JavaScript!
FES proto-oncogene, tyrosine kinase/Tyrosine-protein kinase FES in Human [ChEMBL: CHEMBL5455] [GtoPdb: 2023] [UniProtKB: P07332] There should be some charts here, you may need to enable JavaScript!
HCK proto-oncogene, Src family tyrosine kinase/Tyrosine-protein kinase HCK in Human [ChEMBL: CHEMBL3234] [GtoPdb: 2032] [UniProtKB: P08631] There should be some charts here, you may need to enable JavaScript!
IL2 inducible T cell kinase/Tyrosine-protein kinase ITK/TSK in Human [ChEMBL: CHEMBL2959] [GtoPdb: 2046] [UniProtKB: Q08881] There should be some charts here, you may need to enable JavaScript!
Janus kinase 2/Tyrosine-protein kinase JAK2 in Human [ChEMBL: CHEMBL2971] [GtoPdb: 2048] [UniProtKB: O60674] There should be some charts here, you may need to enable JavaScript!
LYN proto-oncogene, Src family tyrosine kinase/Tyrosine-protein kinase Lyn in Human [ChEMBL: CHEMBL3905] [GtoPdb: 2060] [UniProtKB: P07948] There should be some charts here, you may need to enable JavaScript!
fms related receptor tyrosine kinase 3/Tyrosine-protein kinase receptor FLT3 in Human [ChEMBL: CHEMBL1974] [GtoPdb: 1807] [UniProtKB: P36888] There should be some charts here, you may need to enable JavaScript!
ret proto-oncogene/Tyrosine-protein kinase receptor RET in Human [ChEMBL: CHEMBL2041] [GtoPdb: 2185] [UniProtKB: P07949] There should be some charts here, you may need to enable JavaScript!
TYRO3 protein tyrosine kinase/Tyrosine-protein kinase receptor TYRO3 in Human [ChEMBL: CHEMBL5314] [GtoPdb: 1836] [UniProtKB: Q06418] There should be some charts here, you may need to enable JavaScript!
AXL receptor tyrosine kinase/Tyrosine-protein kinase receptor UFO in Human [ChEMBL: CHEMBL4895] [GtoPdb: 1835] [UniProtKB: P30530] There should be some charts here, you may need to enable JavaScript!
SRC proto-oncogene, non-receptor tyrosine kinase/Tyrosine-protein kinase SRC in Human [ChEMBL: CHEMBL267] [GtoPdb: 2206] [UniProtKB: P12931] There should be some charts here, you may need to enable JavaScript!
YES proto-oncogene 1, Src family tyrosine kinase/Tyrosine-protein kinase YES in Human [ChEMBL: CHEMBL2073] [GtoPdb: 2284] [UniProtKB: P07947] There should be some charts here, you may need to enable JavaScript!
zeta chain of T cell receptor associated protein kinase 70/Tyrosine-protein kinase ZAP-70 in Human [ChEMBL: CHEMBL2803] [GtoPdb: 2285] [UniProtKB: P43403] There should be some charts here, you may need to enable JavaScript!
fms related receptor tyrosine kinase 1/Vascular endothelial growth factor receptor 1 in Human [ChEMBL: CHEMBL1868] [GtoPdb: 1812] [UniProtKB: P17948] There should be some charts here, you may need to enable JavaScript!
kinase insert domain receptor/Vascular endothelial growth factor receptor 2 in Human [ChEMBL: CHEMBL279] [GtoPdb: 1813] [UniProtKB: P35968] There should be some charts here, you may need to enable JavaScript!
mechanistic target of rapamycin kinase in Human [GtoPdb: 2109] [UniProtKB: P42345] There should be some charts here, you may need to enable JavaScript!

DB	Assay description	Assay Type	Standard value	Standard parameter	Original value	Original units	Original parameter	Reference
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3/6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2331053] [GtoPdb: 2937] [UniProtKB: Q16875]
ChEMBL	Inhibition of IPFK2 (unknown origin)	B	5	pIC50	>10000	nM	IC50	J Med Chem (2013) 56: 2218-2234 [PMID:23394126]
ALK receptor tyrosine kinase/ALK tyrosine kinase receptor in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL4247] [GtoPdb: 1839] [UniProtKB: Q9UM73]
ChEMBL	Inhibition of ALK (unknown origin)	B	5.46	pIC50	>3500	nM	IC50	J Med Chem (2013) 56: 2218-2234 [PMID:23394126]
protein kinase AMP-activated non-catalytic subunit beta 1/AMP-activated protein kinase, beta-1 subunit in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3847] [GtoPdb: 1543] [UniProtKB: Q9Y478]
ChEMBL	Inhibition of AMPK (unknown origin)	B	5	pIC50	>10000	nM	IC50	J Med Chem (2013) 56: 2218-2234 [PMID:23394126]
BR serine/threonine kinase 1/BR serine/threonine-protein kinase 1 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL5650] [GtoPdb: 1946] [UniProtKB: Q8TDC3]
ChEMBL	Inhibition of BRSK1 (unknown origin)	B	5	pIC50	>10000	nM	IC50	J Med Chem (2013) 56: 2218-2234 [PMID:23394126]
calcium/calmodulin dependent protein kinase I/CaM kinase I alpha in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2493] [GtoPdb: 1952] [UniProtKB: Q14012]
ChEMBL	Inhibition of CAMK1 (unknown origin)	B	5	pIC50	>10000	nM	IC50	J Med Chem (2013) 56: 2218-2234 [PMID:23394126]
calcium/calmodulin dependent protein kinase IV/CaM kinase IV in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2494] [GtoPdb: 1955] [UniProtKB: Q16566]
ChEMBL	Inhibition of CAMK4 (unknown origin)	B	5	pIC50	>10000	nM	IC50	J Med Chem (2013) 56: 2218-2234 [PMID:23394126]
casein kinase 1 delta/Casein kinase I delta in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2828] [GtoPdb: 1997] [UniProtKB: P48730]
ChEMBL	Inhibition of CK1delta (unknown origin)	B	5	pIC50	>10000	nM	IC50	J Med Chem (2013) 56: 2218-2234 [PMID:23394126]
casein kinase 2, alpha prime polypeptide subunit/casein kinase 2, beta polypeptide subunit/casein kinase 2, alpha 1 polypeptide subunit/Casein kinase II in Human (target type: PROTEIN COMPLEX GROUP) [ChEMBL: CHEMBL2095191] [GtoPdb: 1550, 1551, 1549] [UniProtKB: P19784, P67870, P68400]
ChEMBL	Inhibition of CK2 (unknown origin)	B	5	pIC50	>10000	nM	IC50	J Med Chem (2013) 56: 2218-2234 [PMID:23394126]
cyclin dependent kinase 3/CDK3/cyclin E in Human (target type: PROTEIN COMPLEX GROUP) [ChEMBL: CHEMBL2111444] [GtoPdb: 1975] [UniProtKB: O96020, P24864, Q00526]
ChEMBL	Inhibition of CDK3/Cyclin E (unknown origin)	B	5	pIC50	>10000	nM	IC50	J Med Chem (2013) 56: 2218-2234 [PMID:23394126]
cell division cycle 7/Cell division cycle 7-related protein kinase in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL5443] [GtoPdb: 1960] [UniProtKB: O00311]
ChEMBL	Inhibition of CDC7 (unknown origin)	B	5.46	pIC50	>3500	nM	IC50	J Med Chem (2013) 56: 2218-2234 [PMID:23394126]
Protein kinase G (PKG) 1/cGMP-dependent protein kinase 1 beta in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL4273] [GtoPdb: 1492] [UniProtKB: Q13976]
ChEMBL	Inhibition of PKG1beta (unknown origin)	B	5	pIC50	>10000	nM	IC50	J Med Chem (2013) 56: 2218-2234 [PMID:23394126]
mitogen-activated protein kinase 8/c-Jun N-terminal kinase 1 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2276] [GtoPdb: 1496] [UniProtKB: P45983]
ChEMBL	Inhibition of JNK1alpha2 (unknown origin)	B	5	pIC50	>10000	nM	IC50	J Med Chem (2013) 56: 2218-2234 [PMID:23394126]
ChEMBL	Inhibition of JNK1alpha1 (unknown origin)	B	5	pIC50	>10000	nM	IC50	J Med Chem (2013) 56: 2218-2234 [PMID:23394126]
mitogen-activated protein kinase 10/c-Jun N-terminal kinase 3 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2637] [GtoPdb: 1498] [UniProtKB: P53779]
ChEMBL	Inhibition of JNK3 (unknown origin)	B	5	pIC50	>10000	nM	IC50	J Med Chem (2013) 56: 2218-2234 [PMID:23394126]
cyclin dependent kinase 5/Cyclin-dependent kinase 5/CDK5 activator 1 in Human (target type: PROTEIN COMPLEX) [ChEMBL: CHEMBL1907600] [GtoPdb: 1977] [UniProtKB: Q00535, Q15078]
ChEMBL	Inhibition of CDK5/P25 (unknown origin)	B	5	pIC50	>10000	nM	IC50	J Med Chem (2013) 56: 2218-2234 [PMID:23394126]
death associated protein kinase 2/Death-associated protein kinase 2 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3123] [GtoPdb: 2003] [UniProtKB: Q9UIK4]
ChEMBL	Inhibition of DAPK2 (unknown origin)	B	5	pIC50	>10000	nM	IC50	J Med Chem (2013) 56: 2218-2234 [PMID:23394126]
death associated protein kinase 3/Death-associated protein kinase 3 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2468] [GtoPdb: 2004] [UniProtKB: O43293]
ChEMBL	Inhibition of ZIPK (unknown origin)	B	5	pIC50	>10000	nM	IC50	J Med Chem (2013) 56: 2218-2234 [PMID:23394126]
discoidin domain receptor tyrosine kinase 2/Discoidin domain-containing receptor 2 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL5122] [GtoPdb: 1844] [UniProtKB: Q16832]
ChEMBL	Inhibition of DDR2 (unknown origin)	B	5	pIC50	>10000	nM	IC50	J Med Chem (2013) 56: 2218-2234 [PMID:23394126]
protein kinase, DNA-activated, catalytic subunit/DNA-dependent protein kinase in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3142] [GtoPdb: 2800] [UniProtKB: P78527]
ChEMBL	Inhibition of DNA-PK (unknown origin)	B	5.05	pIC50	8831	nM	IC50	J Med Chem (2013) 56: 2218-2234 [PMID:23394126]
mitogen-activated protein kinase kinase 1/Dual specificity mitogen-activated protein kinase kinase 1 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3587] [GtoPdb: 2062] [UniProtKB: Q02750]
ChEMBL	Inhibition of MEK1 (unknown origin)	B	5.46	pIC50	>3500	nM	IC50	J Med Chem (2013) 56: 2218-2234 [PMID:23394126]
mitogen-activated protein kinase kinase 4/Dual specificity mitogen-activated protein kinase kinase 4 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2897] [GtoPdb: 2065] [UniProtKB: P45985]
ChEMBL	Inhibition of MKK4 (unknown origin)	B	5	pIC50	>10000	nM	IC50	J Med Chem (2013) 56: 2218-2234 [PMID:23394126]
mitogen-activated protein kinase kinase 6/Dual specificity mitogen-activated protein kinase kinase 6 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2171] [GtoPdb: 2067] [UniProtKB: P52564]
ChEMBL	Inhibition of MKK6 (unknown origin)	B	5	pIC50	>10000	nM	IC50	J Med Chem (2013) 56: 2218-2234 [PMID:23394126]
mitogen-activated protein kinase kinase 7/Dual specificity mitogen-activated protein kinase kinase 7 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3530] [GtoPdb: 2068] [UniProtKB: O14733]
ChEMBL	Inhibition of MKK7beta (unknown origin)	B	5	pIC50	>10000	nM	IC50	J Med Chem (2013) 56: 2218-2234 [PMID:23394126]
CDC like kinase 2/Dual specificity protein kinase CLK2 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL4225] [GtoPdb: 1991] [UniProtKB: P49760]
ChEMBL	Inhibition of CLK2 (unknown origin)	B	5	pIC50	>10000	nM	IC50	J Med Chem (2013) 56: 2218-2234 [PMID:23394126]
dual specificity tyrosine phosphorylation regulated kinase 2/Dual-specificity tyrosine-phosphorylation regulated kinase 2 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL4376] [GtoPdb: 2011] [UniProtKB: Q92630]
ChEMBL	Inhibition of DYRK2 (unknown origin)	B	5	pIC50	>10000	nM	IC50	J Med Chem (2013) 56: 2218-2234 [PMID:23394126]
EPH receptor A2/Ephrin type-A receptor 2 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2068] [GtoPdb: 1822] [UniProtKB: P29317]
ChEMBL	Inhibition of EPHA2 (unknown origin)	B	5	pIC50	>10000	nM	IC50	J Med Chem (2013) 56: 2218-2234 [PMID:23394126]
EPH receptor B1/Ephrin type-B receptor 1 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL5072] [GtoPdb: 1830] [UniProtKB: P54762]
ChEMBL	Inhibition of EPHB1 (unknown origin)	B	5	pIC50	>10000	nM	IC50	J Med Chem (2013) 56: 2218-2234 [PMID:23394126]
epidermal growth factor receptor/Epidermal growth factor receptor erbB1 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL203] [GtoPdb: 1797] [UniProtKB: P00533]
ChEMBL	Inhibition of EGFR (unknown origin)	B	5.46	pIC50	>3500	nM	IC50	J Med Chem (2013) 56: 2218-2234 [PMID:23394126]
fibroblast growth factor receptor 1/Fibroblast growth factor receptor 1 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3650] [GtoPdb: 1808] [UniProtKB: P11362]
ChEMBL	Inhibition of FGFR1 (unknown origin)	B	5	pIC50	>10000	nM	IC50	J Med Chem (2013) 56: 2218-2234 [PMID:23394126]
fibroblast growth factor receptor 2/Fibroblast growth factor receptor 2 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL4142] [GtoPdb: 1809] [UniProtKB: P21802]
ChEMBL	Inhibition of FGFR2 (unknown origin)	B	5	pIC50	>10000	nM	IC50	J Med Chem (2013) 56: 2218-2234 [PMID:23394126]
fibroblast growth factor receptor 3/Fibroblast growth factor receptor 3 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2742] [GtoPdb: 1810] [UniProtKB: P22607]
ChEMBL	Inhibition of FGFR3 (unknown origin)	B	5	pIC50	>10000	nM	IC50	J Med Chem (2013) 56: 2218-2234 [PMID:23394126]
fibroblast growth factor receptor 4/Fibroblast growth factor receptor 4 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3973] [GtoPdb: 1811] [UniProtKB: P22455]
ChEMBL	Inhibition of FGFR4 (unknown origin)	B	5	pIC50	>10000	nM	IC50	J Med Chem (2013) 56: 2218-2234 [PMID:23394126]
protein tyrosine kinase 2/Focal adhesion kinase 1 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2695] [GtoPdb: 2180] [UniProtKB: Q05397]
ChEMBL	Inhibition of FAK (unknown origin)	B	5.46	pIC50	>3500	nM	IC50	J Med Chem (2013) 56: 2218-2234 [PMID:23394126]
glycogen synthase kinase 3 alpha/Glycogen synthase kinase-3 alpha in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2850] [GtoPdb: 2029] [UniProtKB: P49840]
ChEMBL	Inhibition of GSK3alpha (unknown origin)	B	5	pIC50	>10000	nM	IC50	J Med Chem (2013) 56: 2218-2234 [PMID:23394126]
glycogen synthase kinase 3 beta/Glycogen synthase kinase-3 beta in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL262] [GtoPdb: 2030] [UniProtKB: P49841]
ChEMBL	Inhibition of GSK3beta (unknown origin)	B	5	pIC50	>10000	nM	IC50	J Med Chem (2013) 56: 2218-2234 [PMID:23394126]
G protein-coupled receptor kinase 5 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL5678] [GtoPdb: 1469] [UniProtKB: P34947]
ChEMBL	Inhibition of GRK5 (unknown origin)	B	5	pIC50	>10000	nM	IC50	J Med Chem (2013) 56: 2218-2234 [PMID:23394126]
heat shock protein 90 alpha family class B member 1/Heat shock protein HSP 90-beta in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL4303] [GtoPdb: 2907] [UniProtKB: P08238]
ChEMBL	Inhibition of HSP90 (unknown origin)	B	5.46	pIC50	>3500	nM	IC50	J Med Chem (2013) 56: 2218-2234 [PMID:23394126]
MET proto-oncogene, receptor tyrosine kinase/Hepatocyte growth factor receptor in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3717] [GtoPdb: 1815] [UniProtKB: P08581]
ChEMBL	Inhibition of MET (unknown origin)	B	5.46	pIC50	>3500	nM	IC50	J Med Chem (2013) 56: 2218-2234 [PMID:23394126]
homeodomain interacting protein kinase 2/Homeodomain-interacting protein kinase 2 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL4576] [GtoPdb: 2034] [UniProtKB: Q9H2X6]
ChEMBL	Inhibition of HIPK2 (unknown origin)	B	5	pIC50	>10000	nM	IC50	J Med Chem (2013) 56: 2218-2234 [PMID:23394126]
component of inhibitor of nuclear factor kappa B kinase complex/Inhibitor of nuclear factor kappa B kinase alpha subunit in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3476] [GtoPdb: 1989] [UniProtKB: O15111]
ChEMBL	Inhibition of IKKalpha (unknown origin)	B	5	pIC50	>10000	nM	IC50	J Med Chem (2013) 56: 2218-2234 [PMID:23394126]
inhibitor of nuclear factor kappa B kinase subunit beta/Inhibitor of nuclear factor kappa B kinase beta subunit in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL1991] [GtoPdb: 2039] [UniProtKB: O14920]
ChEMBL	Inhibition of IKKbeta (unknown origin)	B	5	pIC50	>10000	nM	IC50	J Med Chem (2013) 56: 2218-2234 [PMID:23394126]
Insulin-like growth factor I receptor in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL1957] [GtoPdb: 1801] [UniProtKB: P08069]
ChEMBL	Inhibition of IGF1R (unknown origin)	B	5	pIC50	>10000	nM	IC50	J Med Chem (2013) 56: 2218-2234 [PMID:23394126]
interleukin 1 receptor associated kinase 1/Interleukin-1 receptor-associated kinase 1 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3357] [GtoPdb: 2042] [UniProtKB: P51617]
ChEMBL	Inhibition of IRAK1 (unknown origin)	B	5	pIC50	>10000	nM	IC50	J Med Chem (2013) 56: 2218-2234 [PMID:23394126]
LIM domain kinase 1 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3836] [GtoPdb: 2054] [UniProtKB: P53667]
ChEMBL	Inhibition of LIMK1 (unknown origin)	B	5	pIC50	>10000	nM	IC50	J Med Chem (2013) 56: 2218-2234 [PMID:23394126]
MAPK activated protein kinase 2/MAP kinase-activated protein kinase 2 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2208] [GtoPdb: 2094] [UniProtKB: P49137]
ChEMBL	Inhibition of MAPK2 (unknown origin)	B	5	pIC50	>10000	nM	IC50	J Med Chem (2013) 56: 2218-2234 [PMID:23394126]
MAPK activated protein kinase 3/MAP kinase-activated protein kinase 3 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL4670] [GtoPdb: 2095] [UniProtKB: Q16644]
ChEMBL	Inhibition of MAPKAPK3 (unknown origin)	B	5	pIC50	>10000	nM	IC50	J Med Chem (2013) 56: 2218-2234 [PMID:23394126]
MAPK activated protein kinase 5/MAP kinase-activated protein kinase 5 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3094] [GtoPdb: 2096] [UniProtKB: Q8IW41]
ChEMBL	Inhibition of PRAK (unknown origin)	B	5	pIC50	>10000	nM	IC50	J Med Chem (2013) 56: 2218-2234 [PMID:23394126]
mitogen-activated protein kinase 1/MAP kinase ERK2 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL4040] [GtoPdb: 1495] [UniProtKB: P28482]
ChEMBL	Inhibition of MAPK1 (unknown origin)	B	5	pIC50	>10000	nM	IC50	J Med Chem (2013) 56: 2218-2234 [PMID:23394126]
MAPK interacting serine/threonine kinase 2/MAP kinase signal-integrating kinase 2 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL4204] [GtoPdb: 2105] [UniProtKB: Q9HBH9]
ChEMBL	Inhibition of MNK2 (unknown origin)	B	5	pIC50	>10000	nM	IC50	J Med Chem (2013) 56: 2218-2234 [PMID:23394126]
misshapen like kinase 1/Misshapen-like kinase 1 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL5518] [GtoPdb: 2103] [UniProtKB: Q8N4C8]
ChEMBL	Inhibition of MINK (unknown origin)	B	5	pIC50	>10000	nM	IC50	J Med Chem (2013) 56: 2218-2234 [PMID:23394126]
mitogen-activated protein kinase kinase kinase 5/Mitogen-activated protein kinase kinase kinase 5 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL5285] [GtoPdb: 2080] [UniProtKB: Q99683]
ChEMBL	Inhibition of ASK1 (unknown origin)	B	5	pIC50	>10000	nM	IC50	J Med Chem (2013) 56: 2218-2234 [PMID:23394126]
mitogen-activated protein kinase kinase kinase 9/Mitogen-activated protein kinase kinase kinase 9 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2872] [GtoPdb: 2084] [UniProtKB: P80192]
ChEMBL	Inhibition of MLK1 (unknown origin)	B	5	pIC50	>10000	nM	IC50	J Med Chem (2013) 56: 2218-2234 [PMID:23394126]
mitogen-activated protein kinase kinase kinase kinase 2/Mitogen-activated protein kinase kinase kinase kinase 2 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL5330] [GtoPdb: 2086] [UniProtKB: Q12851]
ChEMBL	Inhibition of GCK (unknown origin)	B	5	pIC50	>10000	nM	IC50	J Med Chem (2013) 56: 2218-2234 [PMID:23394126]
muscle associated receptor tyrosine kinase/Muscle, skeletal receptor tyrosine protein kinase in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL5684] [GtoPdb: 1847] [UniProtKB: O15146]
ChEMBL	Inhibition of MUSK (unknown origin)	B	5	pIC50	>10000	nM	IC50	J Med Chem (2013) 56: 2218-2234 [PMID:23394126]
Testicular receptor 4/Nuclear receptor subfamily 2 group C member 2 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL5716] [GtoPdb: 614] [UniProtKB: P49116]
ChEMBL	Inhibition of TAK1 (unknown origin)	B	5	pIC50	>10000	nM	IC50	J Med Chem (2013) 56: 2218-2234 [PMID:23394126]
PAS domain containing serine/threonine kinase/PAS domain-containing serine/threonine-protein kinase in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL6054] [GtoPdb: 2139] [UniProtKB: Q96RG2]
ChEMBL	Inhibition of PASK (unknown origin)	B	5	pIC50	>10000	nM	IC50	J Med Chem (2013) 56: 2218-2234 [PMID:23394126]
phosphatidylinositol 3-kinase catalytic subunit type 3/Phosphatidylinositol 3-kinase catalytic subunit type 3 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL1075165] [GtoPdb: 2152] [UniProtKB: Q8NEB9]
ChEMBL	Inhibition of VPS34 (unknown origin)	B	5.46	pIC50	>3500	nM	IC50	J Med Chem (2013) 56: 2218-2234 [PMID:23394126]
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/PI3-kinase p110-alpha subunit in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL4005] [GtoPdb: 2153] [UniProtKB: P42336]
ChEMBL	Inhibition of PI3Kalpha (unknown origin) using PIP2 as substrate after 2 hrs by luminescence assay	B	5.52	pIC50	>3000	nM	IC50	J Med Chem (2013) 56: 2218-2234 [PMID:23394126]
ChEMBL	Inhibition of PI3Kalpha (unknown origin)	B	5.52	pIC50	>3000	nM	IC50	J Med Chem (2013) 56: 2218-2234 [PMID:23394126]
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta/PI3-kinase p110-beta subunit in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3145] [GtoPdb: 2154] [UniProtKB: P42338]
ChEMBL	Inhibition of PI3Kbeta (unknown origin)	B	5.3	pIC50	>5000	nM	IC50	J Med Chem (2013) 56: 2218-2234 [PMID:23394126]
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta/PI3-kinase p110-delta subunit in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3130] [GtoPdb: 2155] [UniProtKB: O00329]
ChEMBL	Inhibition of PI3Kdelta (unknown origin)	B	5.3	pIC50	>5000	nM	IC50	J Med Chem (2013) 56: 2218-2234 [PMID:23394126]
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma/PI3-kinase p110-gamma subunit in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3267] [GtoPdb: 2156] [UniProtKB: P48736]
ChEMBL	Inhibition of PI3Kgamma (unknown origin)	B	5.3	pIC50	>5000	nM	IC50	J Med Chem (2013) 56: 2218-2234 [PMID:23394126]
platelet derived growth factor receptor beta/Platelet-derived growth factor receptor beta in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL1913] [GtoPdb: 1804] [UniProtKB: P09619]
ChEMBL	Inhibition of PDGFRbeta (unknown origin)	B	5.46	pIC50	>3500	nM	IC50	J Med Chem (2013) 56: 2218-2234 [PMID:23394126]
protein kinase C alpha/Protein kinase C alpha in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL299] [GtoPdb: 1482] [UniProtKB: P17252]
ChEMBL	Inhibition of PKCalpha (unknown origin)	B	5	pIC50	>10000	nM	IC50	J Med Chem (2013) 56: 2218-2234 [PMID:23394126]
protein kinase C beta/Protein kinase C beta in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3045] [GtoPdb: 1483] [UniProtKB: P05771]
ChEMBL	Inhibition of PKCbeta2 (unknown origin)	B	5	pIC50	>10000	nM	IC50	J Med Chem (2013) 56: 2218-2234 [PMID:23394126]
ChEMBL	Inhibition of PKCbeta1 (unknown origin)	B	5	pIC50	>10000	nM	IC50	J Med Chem (2013) 56: 2218-2234 [PMID:23394126]
protein kinase C delta/Protein kinase C delta in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2996] [GtoPdb: 1485] [UniProtKB: Q05655]
ChEMBL	Inhibition of PKCdelta (unknown origin)	B	5	pIC50	>10000	nM	IC50	J Med Chem (2013) 56: 2218-2234 [PMID:23394126]
protein kinase C epsilon/Protein kinase C epsilon in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3582] [GtoPdb: 1486] [UniProtKB: Q02156]
ChEMBL	Inhibition of PKCepsilon (unknown origin)	B	5	pIC50	>10000	nM	IC50	J Med Chem (2013) 56: 2218-2234 [PMID:23394126]
protein kinase C eta/Protein kinase C eta in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3616] [GtoPdb: 1487] [UniProtKB: P24723]
ChEMBL	Inhibition of PKCeta (unknown origin)	B	5	pIC50	>10000	nM	IC50	J Med Chem (2013) 56: 2218-2234 [PMID:23394126]
protein kinase C gamma/Protein kinase C gamma in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2938] [GtoPdb: 1484] [UniProtKB: P05129]
ChEMBL	Inhibition of PKCgamma (unknown origin)	B	5	pIC50	>10000	nM	IC50	J Med Chem (2013) 56: 2218-2234 [PMID:23394126]
protein kinase C iota/Protein kinase C iota in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2598] [GtoPdb: 1490] [UniProtKB: P41743]
ChEMBL	Inhibition of PKCiota (unknown origin)	B	5	pIC50	>10000	nM	IC50	J Med Chem (2013) 56: 2218-2234 [PMID:23394126]
protein kinase D1/Protein kinase C mu in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3863] [GtoPdb: 1489] [UniProtKB: Q15139]
ChEMBL	Inhibition of PKCmu (unknown origin)	B	5	pIC50	>10000	nM	IC50	J Med Chem (2013) 56: 2218-2234 [PMID:23394126]
protein kinase C theta/Protein kinase C theta in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3920] [GtoPdb: 1488] [UniProtKB: Q04759]
ChEMBL	Inhibition of PKCtheta (unknown origin)	B	5	pIC50	>10000	nM	IC50	J Med Chem (2013) 56: 2218-2234 [PMID:23394126]
protein kinase C zeta/Protein kinase C zeta in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3438] [GtoPdb: 1491] [UniProtKB: Q05513]
ChEMBL	Inhibition of PKCzeta (unknown origin)	B	5	pIC50	>10000	nM	IC50	J Med Chem (2013) 56: 2218-2234 [PMID:23394126]
protein kinase N2/Protein kinase N2 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3032] [GtoPdb: 1521] [UniProtKB: Q16513]
ChEMBL	Inhibition of PRK2 (unknown origin)	B	5	pIC50	>10000	nM	IC50	J Med Chem (2013) 56: 2218-2234 [PMID:23394126]
protein tyrosine kinase 2 beta/Protein tyrosine kinase 2 beta in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL5469] [GtoPdb: 2181] [UniProtKB: Q14289]
ChEMBL	Inhibition of PYK2 (unknown origin)	B	5	pIC50	>10000	nM	IC50	J Med Chem (2013) 56: 2218-2234 [PMID:23394126]
MER proto-oncogene, tyrosine kinase/Proto-oncogene tyrosine-protein kinase MER in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL5331] [GtoPdb: 1837] [UniProtKB: Q12866]
ChEMBL	Inhibition of MER (unknown origin)	B	5	pIC50	>10000	nM	IC50	J Med Chem (2013) 56: 2218-2234 [PMID:23394126]
c-ros oncogene 1, receptor tyrosine kinase/Proto-oncogene tyrosine-protein kinase ROS in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL5568] [GtoPdb: 1840] [UniProtKB: P08922]
ChEMBL	Inhibition of ROS (unknown origin)	B	5	pIC50	>10000	nM	IC50	J Med Chem (2013) 56: 2218-2234 [PMID:23394126]
pyruvate dehydrogenase kinase 1/Pyruvate dehydrogenase kinase isoform 1 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL4766] [GtoPdb: 2915] [UniProtKB: Q15118]
ChEMBL	Inhibition of PDK1 (unknown origin)	B	5.46	pIC50	>3500	nM	IC50	J Med Chem (2013) 56: 2218-2234 [PMID:23394126]
erb-b2 receptor tyrosine kinase 2/Receptor protein-tyrosine kinase erbB-2 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL1824] [GtoPdb: 2019] [UniProtKB: P04626]
ChEMBL	Inhibition of ERBB2 (unknown origin)	B	5.46	pIC50	>3500	nM	IC50	J Med Chem (2013) 56: 2218-2234 [PMID:23394126]
Rho associated coiled-coil containing protein kinase 1/Rho-associated protein kinase 1 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3231] [GtoPdb: 1503] [UniProtKB: Q13464]
ChEMBL	Inhibition of ROCK1 (unknown origin)	B	5	pIC50	>10000	nM	IC50	J Med Chem (2013) 56: 2218-2234 [PMID:23394126]
Rho associated coiled-coil containing protein kinase 2/Rho-associated protein kinase 2 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2973] [GtoPdb: 1504] [UniProtKB: O75116]
ChEMBL	Inhibition of ROCK2 (unknown origin)	B	5	pIC50	>10000	nM	IC50	J Med Chem (2013) 56: 2218-2234 [PMID:23394126]
ribosomal protein S6 kinase B1/Ribosomal protein S6 kinase 1 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL4501] [GtoPdb: 1525] [UniProtKB: P23443]
ChEMBL	Inhibition of p70S6K (unknown origin)	B	5.46	pIC50	>3500	nM	IC50	J Med Chem (2013) 56: 2218-2234 [PMID:23394126]
ribosomal protein S6 kinase A1/Ribosomal protein S6 kinase alpha 1 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2553] [GtoPdb: 1527] [UniProtKB: Q15418]
ChEMBL	Inhibition of RSK1 (unknown origin)	B	5	pIC50	>10000	nM	IC50	J Med Chem (2013) 56: 2218-2234 [PMID:23394126]
ribosomal protein S6 kinase A2/Ribosomal protein S6 kinase alpha 2 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3906] [GtoPdb: 1529] [UniProtKB: Q15349]
ChEMBL	Inhibition of RSK3 (unknown origin)	B	5	pIC50	>10000	nM	IC50	J Med Chem (2013) 56: 2218-2234 [PMID:23394126]
ribosomal protein S6 kinase A3/Ribosomal protein S6 kinase alpha 3 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2345] [GtoPdb: 1528] [UniProtKB: P51812]
ChEMBL	Inhibition of RSK2 (unknown origin)	B	5	pIC50	>10000	nM	IC50	J Med Chem (2013) 56: 2218-2234 [PMID:23394126]
ribosomal protein S6 kinase A5/Ribosomal protein S6 kinase alpha 5 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL4237] [GtoPdb: 1523] [UniProtKB: O75582]
ChEMBL	Inhibition of MSK1 (unknown origin)	B	5	pIC50	>10000	nM	IC50	J Med Chem (2013) 56: 2218-2234 [PMID:23394126]
ribosomal protein S6 kinase A6/Ribosomal protein S6 kinase alpha 6 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL4924] [GtoPdb: 1530] [UniProtKB: Q9UK32]
ChEMBL	Inhibition of RSK4 (unknown origin)	B	5	pIC50	>10000	nM	IC50	J Med Chem (2013) 56: 2218-2234 [PMID:23394126]
serine/threonine kinase 10/Serine/threonine-protein kinase 10 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3981] [GtoPdb: 2211] [UniProtKB: O94804]
ChEMBL	Inhibition of LOK (unknown origin)	B	5	pIC50	>10000	nM	IC50	J Med Chem (2013) 56: 2218-2234 [PMID:23394126]
serine/threonine kinase 11/Serine/threonine-protein kinase 11 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL5606] [GtoPdb: 2212] [UniProtKB: Q15831]
ChEMBL	Inhibition of LKB1 (unknown origin)	B	5	pIC50	>10000	nM	IC50	J Med Chem (2013) 56: 2218-2234 [PMID:23394126]
serine/threonine kinase 33/Serine/threonine-protein kinase 33 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL6005] [GtoPdb: 2221] [UniProtKB: Q9BYT3]
ChEMBL	Inhibition of STK33 (unknown origin)	B	5	pIC50	>10000	nM	IC50	J Med Chem (2013) 56: 2218-2234 [PMID:23394126]
AKT serine/threonine kinase 1/Serine/threonine-protein kinase AKT in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL4282] [GtoPdb: 1479] [UniProtKB: P31749]
ChEMBL	Inhibition of AKT1 (unknown origin)	B	5.46	pIC50	>3500	nM	IC50	J Med Chem (2013) 56: 2218-2234 [PMID:23394126]
AKT serine/threonine kinase 2/Serine/threonine-protein kinase AKT2 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2431] [GtoPdb: 1480] [UniProtKB: P31751]
ChEMBL	Inhibition of AKT2 (unknown origin)	B	5	pIC50	>10000	nM	IC50	J Med Chem (2013) 56: 2218-2234 [PMID:23394126]
AKT serine/threonine kinase 3/Serine/threonine-protein kinase AKT3 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL4816] [GtoPdb: 2286] [UniProtKB: Q9Y243]
ChEMBL	Inhibition of AKT3 (unknown origin)	B	5	pIC50	>10000	nM	IC50	J Med Chem (2013) 56: 2218-2234 [PMID:23394126]
aurora kinase A/Serine/threonine-protein kinase Aurora-A in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL4722] [GtoPdb: 1936] [UniProtKB: O14965]
ChEMBL	Inhibition of Aurora kinase A (unknown origin)	B	5	pIC50	>10000	nM	IC50	J Med Chem (2013) 56: 2218-2234 [PMID:23394126]
checkpoint kinase 1/Serine/threonine-protein kinase Chk1 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL4630] [GtoPdb: 1987] [UniProtKB: O14757]
ChEMBL	Inhibition of CHK1 (unknown origin)	B	5.46	pIC50	>3500	nM	IC50	J Med Chem (2013) 56: 2218-2234 [PMID:23394126]
checkpoint kinase 2/Serine/threonine-protein kinase Chk2 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2527] [GtoPdb: 1988] [UniProtKB: O96017]
ChEMBL	Inhibition of CHK2 (unknown origin)	B	5	pIC50	>10000	nM	IC50	J Med Chem (2013) 56: 2218-2234 [PMID:23394126]
protein kinase D2/Serine/threonine-protein kinase D2 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL4900] [GtoPdb: 2173] [UniProtKB: Q9BZL6]
ChEMBL	Inhibition of PKD2 (unknown origin)	B	5	pIC50	>10000	nM	IC50	J Med Chem (2013) 56: 2218-2234 [PMID:23394126]
histone H3 associated protein kinase/Serine/threonine-protein kinase haspin in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL1075163] [GtoPdb: 2028] [UniProtKB: Q8TF76]
ChEMBL	Inhibition of Haspin (unknown origin)	B	5	pIC50	>10000	nM	IC50	J Med Chem (2013) 56: 2218-2234 [PMID:23394126]
microtubule affinity regulating kinase 1/Serine/threonine-protein kinase MARK1 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL5940] [GtoPdb: 2097] [UniProtKB: Q9P0L2]
ChEMBL	Inhibition of MARK1 (unknown origin)	B	5	pIC50	>10000	nM	IC50	J Med Chem (2013) 56: 2218-2234 [PMID:23394126]
serine/threonine kinase 4/Serine/threonine-protein kinase MST1 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL4598] [GtoPdb: 2225] [UniProtKB: Q13043]
ChEMBL	Inhibition of MST1 (unknown origin)	B	5	pIC50	>10000	nM	IC50	J Med Chem (2013) 56: 2218-2234 [PMID:23394126]
NIMA related kinase 2/Serine/threonine-protein kinase NEK2 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3835] [GtoPdb: 2117] [UniProtKB: P51955]
ChEMBL	Inhibition of NEK2 (unknown origin)	B	5	pIC50	>10000	nM	IC50	J Med Chem (2013) 56: 2218-2234 [PMID:23394126]
NIMA related kinase 7/Serine/threonine-protein kinase NEK7 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL4849] [GtoPdb: 2122] [UniProtKB: Q8TDX7]
ChEMBL	Inhibition of NEK7 (unknown origin)	B	5	pIC50	>10000	nM	IC50	J Med Chem (2013) 56: 2218-2234 [PMID:23394126]
nemo like kinase/Serine/threonine protein kinase NLK in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL5364] [GtoPdb: 2125] [UniProtKB: Q9UBE8]
ChEMBL	Inhibition of NLK (unknown origin)	B	5	pIC50	>10000	nM	IC50	J Med Chem (2013) 56: 2218-2234 [PMID:23394126]
p21 (RAC1) activated kinase 3/Serine/threonine-protein kinase PAK 3 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2999] [GtoPdb: 2135] [UniProtKB: O75914]
ChEMBL	Inhibition of PAK3 (unknown origin)	B	5	pIC50	>10000	nM	IC50	J Med Chem (2013) 56: 2218-2234 [PMID:23394126]
p21 (RAC1) activated kinase 6/Serine/threonine-protein kinase PAK6 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL4311] [GtoPdb: 2137] [UniProtKB: Q9NQU5]
ChEMBL	Inhibition of PAK6 (unknown origin)	B	5	pIC50	>10000	nM	IC50	J Med Chem (2013) 56: 2218-2234 [PMID:23394126]
Pim-1 proto-oncogene, serine/threonine kinase/Serine/threonine-protein kinase PIM1 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2147] [GtoPdb: 2158] [UniProtKB: P11309]
ChEMBL	Inhibition of PIM1 (unknown origin)	B	5.46	pIC50	>3500	nM	IC50	J Med Chem (2013) 56: 2218-2234 [PMID:23394126]
polo like kinase 1/Serine/threonine-protein kinase PLK1 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3024] [GtoPdb: 2168] [UniProtKB: P53350]
ChEMBL	Inhibition of PLK1 (unknown origin)	B	5	pIC50	>10000	nM	IC50	J Med Chem (2013) 56: 2218-2234 [PMID:23394126]
polo like kinase 3/Serine/threonine-protein kinase PLK3 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL4897] [GtoPdb: 2170] [UniProtKB: Q9H4B4]
ChEMBL	Inhibition of PLK3 (unknown origin)	B	5	pIC50	>10000	nM	IC50	J Med Chem (2013) 56: 2218-2234 [PMID:23394126]
Raf-1 proto-oncogene, serine/threonine kinase/Serine/threonine-protein kinase RAF in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL1906] [GtoPdb: 2184] [UniProtKB: P04049]
ChEMBL	Inhibition of cRAF (unknown origin)	B	5.46	pIC50	>3500	nM	IC50	J Med Chem (2013) 56: 2218-2234 [PMID:23394126]
receptor interacting serine/threonine kinase 2/Serine/threonine-protein kinase RIPK2 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL5014] [GtoPdb: 2190] [UniProtKB: O43353]
ChEMBL	Inhibition of RIPK2 (unknown origin)	B	5	pIC50	>10000	nM	IC50	J Med Chem (2013) 56: 2218-2234 [PMID:23394126]
serum/glucocorticoid regulated kinase 1/Serine/threonine-protein kinase Sgk1 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2343] [GtoPdb: 1534] [UniProtKB: O00141]
ChEMBL	Inhibition of SGK (unknown origin)	B	5	pIC50	>10000	nM	IC50	J Med Chem (2013) 56: 2218-2234 [PMID:23394126]
serum/glucocorticoid regulated kinase 2/Serine/threonine-protein kinase Sgk2 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL5794] [GtoPdb: 1535] [UniProtKB: Q9HBY8]
ChEMBL	Inhibition of SGK2 (unknown origin)	B	5	pIC50	>10000	nM	IC50	J Med Chem (2013) 56: 2218-2234 [PMID:23394126]
serum/glucocorticoid regulated kinase family member 3/Serine/threonine-protein kinase Sgk3 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL6186] [GtoPdb: 1536] [UniProtKB: Q96BR1]
ChEMBL	Inhibition of SGK3 (unknown origin)	B	5	pIC50	>10000	nM	IC50	J Med Chem (2013) 56: 2218-2234 [PMID:23394126]
SRSF protein kinase 3/Serine/threonine-protein kinase SRPK3 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL5415] [GtoPdb: 2210] [UniProtKB: Q9UPE1]
ChEMBL	Inhibition of MSSK1 (unknown origin)	B	5	pIC50	>10000	nM	IC50	J Med Chem (2013) 56: 2218-2234 [PMID:23394126]
TAO kinase 1/Serine/threonine-protein kinase TAO1 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL5261] [GtoPdb: 2233] [UniProtKB: Q7L7X3]
ChEMBL	Inhibition of TAO1 (unknown origin)	B	5	pIC50	>10000	nM	IC50	J Med Chem (2013) 56: 2218-2234 [PMID:23394126]
TANK binding kinase 1/Serine/threonine-protein kinase TBK1 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL5408] [GtoPdb: 2237] [UniProtKB: Q9UHD2]
ChEMBL	Inhibition of TBK1 (unknown origin)	B	5	pIC50	>10000	nM	IC50	J Med Chem (2013) 56: 2218-2234 [PMID:23394126]
unc-51 like autophagy activating kinase 2/Serine/threonine-protein kinase ULK2 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL5435] [GtoPdb: 2272] [UniProtKB: Q8IYT8]
ChEMBL	Inhibition of ULK2 (unknown origin)	B	5	pIC50	>10000	nM	IC50	J Med Chem (2013) 56: 2218-2234 [PMID:23394126]
VRK serine/threonine kinase 2/Serine/threonine-protein kinase VRK2 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL1649059] [GtoPdb: 2276] [UniProtKB: Q86Y07]
ChEMBL	Inhibition of VRK2 (unknown origin)	B	5	pIC50	>10000	nM	IC50	J Med Chem (2013) 56: 2218-2234 [PMID:23394126]
WNK lysine deficient protein kinase 2/Serine/threonine-protein kinase WNK2 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL5639] [GtoPdb: 2281] [UniProtKB: Q9Y3S1]
ChEMBL	Inhibition of WNK2 (unknown origin)	B	5	pIC50	>10000	nM	IC50	J Med Chem (2013) 56: 2218-2234 [PMID:23394126]
KIT proto-oncogene, receptor tyrosine kinase/Stem cell growth factor receptor in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL1936] [GtoPdb: 1805] [UniProtKB: P10721]
ChEMBL	Inhibition of KIT (unknown origin)	B	5.46	pIC50	>3500	nM	IC50	J Med Chem (2013) 56: 2218-2234 [PMID:23394126]
testis specific serine kinase 1B/Testis-specific serine/threonine-protein kinase 1 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL6003] [GtoPdb: 2257] [UniProtKB: Q9BXA7]
ChEMBL	Inhibition of TSSK1 (unknown origin)	B	5	pIC50	>10000	nM	IC50	J Med Chem (2013) 56: 2218-2234 [PMID:23394126]
tyrosine kinase non receptor 2/Tyrosine kinase non-receptor protein 2 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL4599] [GtoPdb: 2246] [UniProtKB: Q07912]
ChEMBL	Inhibition of ACK1 (unknown origin)	B	5	pIC50	>10000	nM	IC50	J Med Chem (2013) 56: 2218-2234 [PMID:23394126]
ABL proto-oncogene 1, non-receptor tyrosine kinase/Tyrosine-protein kinase ABL in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL1862] [GtoPdb: 1923] [UniProtKB: P00519]
ChEMBL	Inhibition of ABL (unknown origin)	B	5	pIC50	>10000	nM	IC50	J Med Chem (2013) 56: 2218-2234 [PMID:23394126]
ABL proto-oncogene 2, non-receptor tyrosine kinase/Tyrosine-protein kinase ABL2 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL4014] [GtoPdb: 1924] [UniProtKB: P42684]
ChEMBL	Inhibition of ARG (unknown origin)	B	5	pIC50	>10000	nM	IC50	J Med Chem (2013) 56: 2218-2234 [PMID:23394126]
BLK proto-oncogene, Src family tyrosine kinase/Tyrosine-protein kinase BLK in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2250] [GtoPdb: 1940] [UniProtKB: P51451]
ChEMBL	Inhibition of BLK (unknown origin)	B	5	pIC50	>10000	nM	IC50	J Med Chem (2013) 56: 2218-2234 [PMID:23394126]
protein tyrosine kinase 6/Tyrosine-protein kinase BRK in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL4601] [GtoPdb: 2182] [UniProtKB: Q13882]
ChEMBL	Inhibition of BRK (unknown origin)	B	5	pIC50	>10000	nM	IC50	J Med Chem (2013) 56: 2218-2234 [PMID:23394126]
C-terminal Src kinase/Tyrosine-protein kinase CSK in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2634] [GtoPdb: 1994] [UniProtKB: P41240]
ChEMBL	Inhibition of CSK (unknown origin)	B	5	pIC50	>10000	nM	IC50	J Med Chem (2013) 56: 2218-2234 [PMID:23394126]
FES proto-oncogene, tyrosine kinase/Tyrosine-protein kinase FES in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL5455] [GtoPdb: 2023] [UniProtKB: P07332]
ChEMBL	Inhibition of FES (unknown origin)	B	5	pIC50	>10000	nM	IC50	J Med Chem (2013) 56: 2218-2234 [PMID:23394126]
HCK proto-oncogene, Src family tyrosine kinase/Tyrosine-protein kinase HCK in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3234] [GtoPdb: 2032] [UniProtKB: P08631]
ChEMBL	Inhibition of HCK (unknown origin)	B	5	pIC50	>10000	nM	IC50	J Med Chem (2013) 56: 2218-2234 [PMID:23394126]
IL2 inducible T cell kinase/Tyrosine-protein kinase ITK/TSK in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2959] [GtoPdb: 2046] [UniProtKB: Q08881]
ChEMBL	Inhibition of ITK (unknown origin)	B	5	pIC50	>10000	nM	IC50	J Med Chem (2013) 56: 2218-2234 [PMID:23394126]
Janus kinase 2/Tyrosine-protein kinase JAK2 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2971] [GtoPdb: 2048] [UniProtKB: O60674]
ChEMBL	Inhibition of JAK2 (unknown origin)	B	5.46	pIC50	>3500	nM	IC50	J Med Chem (2013) 56: 2218-2234 [PMID:23394126]
LYN proto-oncogene, Src family tyrosine kinase/Tyrosine-protein kinase Lyn in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3905] [GtoPdb: 2060] [UniProtKB: P07948]
ChEMBL	Inhibition of LYN (unknown origin)	B	5	pIC50	>10000	nM	IC50	J Med Chem (2013) 56: 2218-2234 [PMID:23394126]
fms related receptor tyrosine kinase 3/Tyrosine-protein kinase receptor FLT3 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL1974] [GtoPdb: 1807] [UniProtKB: P36888]
ChEMBL	Inhibition of FLT3 (unknown origin)	B	5.46	pIC50	>3500	nM	IC50	J Med Chem (2013) 56: 2218-2234 [PMID:23394126]
ret proto-oncogene/Tyrosine-protein kinase receptor RET in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2041] [GtoPdb: 2185] [UniProtKB: P07949]
ChEMBL	Inhibition of RET (unknown origin)	B	5	pIC50	>10000	nM	IC50	J Med Chem (2013) 56: 2218-2234 [PMID:23394126]
TYRO3 protein tyrosine kinase/Tyrosine-protein kinase receptor TYRO3 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL5314] [GtoPdb: 1836] [UniProtKB: Q06418]
ChEMBL	Inhibition of RSE (unknown origin)	B	5	pIC50	>10000	nM	IC50	J Med Chem (2013) 56: 2218-2234 [PMID:23394126]
AXL receptor tyrosine kinase/Tyrosine-protein kinase receptor UFO in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL4895] [GtoPdb: 1835] [UniProtKB: P30530]
ChEMBL	Inhibition of AXL (unknown origin)	B	5	pIC50	>10000	nM	IC50	J Med Chem (2013) 56: 2218-2234 [PMID:23394126]
SRC proto-oncogene, non-receptor tyrosine kinase/Tyrosine-protein kinase SRC in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL267] [GtoPdb: 2206] [UniProtKB: P12931]
ChEMBL	Inhibition of SRC (unknown origin)	B	5.46	pIC50	>3500	nM	IC50	J Med Chem (2013) 56: 2218-2234 [PMID:23394126]
YES proto-oncogene 1, Src family tyrosine kinase/Tyrosine-protein kinase YES in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2073] [GtoPdb: 2284] [UniProtKB: P07947]
ChEMBL	Inhibition of YES (unknown origin)	B	5	pIC50	>10000	nM	IC50	J Med Chem (2013) 56: 2218-2234 [PMID:23394126]
zeta chain of T cell receptor associated protein kinase 70/Tyrosine-protein kinase ZAP-70 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2803] [GtoPdb: 2285] [UniProtKB: P43403]
ChEMBL	Inhibition of ZAP70 (unknown origin)	B	5	pIC50	>10000	nM	IC50	J Med Chem (2013) 56: 2218-2234 [PMID:23394126]
fms related receptor tyrosine kinase 1/Vascular endothelial growth factor receptor 1 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL1868] [GtoPdb: 1812] [UniProtKB: P17948]
ChEMBL	Inhibition of FLT1 (unknown origin)	B	5.46	pIC50	>3500	nM	IC50	J Med Chem (2013) 56: 2218-2234 [PMID:23394126]
kinase insert domain receptor/Vascular endothelial growth factor receptor 2 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL279] [GtoPdb: 1813] [UniProtKB: P35968]
ChEMBL	Inhibition of KDR (unknown origin)	B	5.46	pIC50	>3500	nM	IC50	J Med Chem (2013) 56: 2218-2234 [PMID:23394126]
mechanistic target of rapamycin kinase in Human [GtoPdb: 2109] [UniProtKB: P42345]
GtoPdb	-	-	8	pIC50	9.9	nM	IC50	J Med Chem (2013) 56: 2218-34 [PMID:23394126]

ChEMBL data shown on this page come from version 34:

Zdrazil B, Felix E, Hunter F, Manners EJ, Blackshaw J, Corbett S, de Veij M, Ioannidis H, Lopez DM, Mosquera JF, Magarinos MP, Bosc N, Arcila R, Kizilören T, Gaulton A, Bento AP, Adasme MF, Monecke P, Landrum GA, Leach AR. (2024). The ChEMBL Database in 2023: a drug discovery platform spanning multiple bioactivity data types and time periods. Nucleic Acids Res., 52(D1). DOI: 10.1093/nar/gkad1004. [EPMCID:10767899] [PMID:37933841]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]