Click here for a description of the charts and data table
Please tell us if you are using this feature and what you think!
ChEMBL ligand: CHEMBL78535 (Ancriviroc, SCH351125, SCH-351125) |
---|
There should be some charts here, you may need to enable JavaScript!
|
DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
---|---|---|---|---|---|---|---|---|
CCR5/C-C chemokine receptor type 5 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL274] [GtoPdb: 62] [UniProtKB: P51681] | ||||||||
GtoPdb | - | - | 8.9 | pKd | - | - | - | Antimicrob Agents Chemother (2005) 49: 4911-9 [PMID:16304152] |
ChEMBL | Inhibition of RANTES binding to C-C chemokine receptor type 5 | B | 8.68 | pKi | 2.1 | nM | Ki | J. Med. Chem. (2001) 44: 3339-3342 [PMID:11585437] |
ChEMBL | Inhibition of RANTES binding to the human C-C chemokine receptor type 5 (CCR5) | B | 8.68 | pKi | 2.1 | nM | Ki | J. Med. Chem. (2003) 46: 4501-4515 [PMID:14521412] |
CCR5/C-C chemokine receptor type 5 in Mouse (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3676] [GtoPdb: 62] [UniProtKB: P51682] | ||||||||
ChEMBL | Inhibition of RANTES binding to Chemokine receptor type 5 receptor from NIH 3T3 cells | B | 8.68 | pKi | 2.1 | nM | Ki | J. Med. Chem. (2002) 45: 3143-3160 [PMID:12086500] |
ChEMBL data shown on this page come from version 31:
Gaulton A, Hersey A, Nowotka M, Bento AP, Chambers J, Mendez D, Mutowo P, Atkinson F, Bellis LJ, CibriƔn-Uhalte E, Davies M, Dedman N, Karlsson A, MagariƱos MP, Overington JP, Papadatos G, Smit I, Leach AR. (2017) 'The ChEMBL database in 2017.' Nucleic Acids Res., 45(D1). DOI: 10.1093/nar/gkw1074. [PMCID:5210557]