LB42908 [Ligand Id: 8028] activity data from GtoPdb

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  • farnesyltransferase, CAAX box, beta in Human [GtoPdb: 2826] [UniProtKB: P49356]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
farnesyltransferase, CAAX box, beta in Human [GtoPdb: 2826] [UniProtKB: P49356]
GtoPdb Measured as inhibition of FTase transfer of [3H]-farnesylpyrophosphate (FPP) to HRAS (0.9nM) or NRAS (2.4nM) - 9.05 pIC50 0.9 nM IC50 Bioorg Med Chem Lett (2001) 11: 3069-72 [PMID:11714612]

Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.