compound 2-13-1 [PMID: 24900824] [Ligand Id: 8112] activity data from GtoPdb and ChEMBL

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ChEMBL ligand: CHEMBL3260329
  • BUB1 mitotic checkpoint serine/threonine kinase/Mitotic checkpoint serine/threonine-protein kinase BUB1 in Human [ChEMBL: CHEMBL1772932] [GtoPdb: 1949] [UniProtKB: O43683]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
BUB1 mitotic checkpoint serine/threonine kinase/Mitotic checkpoint serine/threonine-protein kinase BUB1 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL1772932] [GtoPdb: 1949] [UniProtKB: O43683]
GtoPdb - - 7.52 pIC50 30 nM IC50 ACS Med Chem Lett (2014) 5: 280-1 [PMID:24900824]
ChEMBL Inhibition of Bub1 kinase (unknown origin) by TR-FRET kinase assay B 7.52 pIC50 30 nM IC50 ACS Med. Chem. Lett. (2014) 5: 280-281 [PMID:24900824]

ChEMBL data shown on this page come from version 28:

Gaulton A, Hersey A, Nowotka M, Bento AP, Chambers J, Mendez D, Mutowo P, Atkinson F, Bellis LJ, CibriƔn-Uhalte E, Davies M, Dedman N, Karlsson A, MagariƱos MP, Overington JP, Papadatos G, Smit I, Leach AR. (2017) 'The ChEMBL database in 2017.' Nucleic Acids Res., 45(D1). DOI: 10.1093/nar/gkw1074. [PMCID:5210557]