compound 3 [PMID: 19097791] [Ligand Id: 8185] activity data from GtoPdb and ChEMBL

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ChEMBL ligand: CHEMBL514197
  • cyclin dependent kinase 2/Cyclin-dependent kinase 2 in Human [ChEMBL: CHEMBL301] [GtoPdb: 1973] [UniProtKB: P24941]
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  • protein kinase C zeta/Protein kinase C zeta in Human [ChEMBL: CHEMBL3438] [GtoPdb: 1491] [UniProtKB: Q05513]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
cyclin dependent kinase 2/Cyclin-dependent kinase 2 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL301] [GtoPdb: 1973] [UniProtKB: P24941]
ChEMBL Inhibition of human CDK2 B 8.39 pIC50 4.1 nM IC50 Bioorg. Med. Chem. Lett. (2009) 19: 908-911 [PMID:19097791]
GtoPdb - - 8.39 pIC50 4.1 nM IC50 Bioorg Med Chem Lett (2009) 19: 908-11 [PMID:19097791]
protein kinase C zeta/Protein kinase C zeta in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3438] [GtoPdb: 1491] [UniProtKB: Q05513]
ChEMBL Inhibition of human PKCzeta B 8.65 pIC50 2.26 nM IC50 Bioorg. Med. Chem. Lett. (2009) 19: 908-911 [PMID:19097791]
GtoPdb - - 8.65 pIC50 2.26 nM IC50 Bioorg Med Chem Lett (2009) 19: 908-11 [PMID:19097791]

ChEMBL data shown on this page come from version 31:

Gaulton A, Hersey A, Nowotka M, Bento AP, Chambers J, Mendez D, Mutowo P, Atkinson F, Bellis LJ, Cibrián-Uhalte E, Davies M, Dedman N, Karlsson A, Magariños MP, Overington JP, Papadatos G, Smit I, Leach AR. (2017) 'The ChEMBL database in 2017.' Nucleic Acids Res., 45(D1). DOI: 10.1093/nar/gkw1074. [PMCID:5210557]