ZD-7155 [Ligand Id: 8324] activity data from GtoPdb and ChEMBL
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| ChEMBL ligand: CHEMBL159096 (ZD-7155) |
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| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
|---|---|---|---|---|---|---|---|---|
| Type-1 angiotensin II receptor in Guinea pig (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL1671613] [UniProtKB: Q9WV26] | ||||||||
| ChEMBL | In vitro antagonistic potency against Angiotensin II receptor, type 1 in guinea pig adrenal membrane | F | 8.42 | pIC50 | 3.8 | nM | IC50 | J Med Chem (1996) 39: 625-656 [PMID:8576904] |
| ChEMBL | Binding affinity to angiotensin AT1 receptor in guinea pig adrenal cortex membranes | B | 8.42 | pIC50 | 3.8 | nM | IC50 | Bioorg Med Chem (2010) 18: 8418-8456 [PMID:21071232] |
| AT1 receptor in Guinea pig [GtoPdb: 34] | ||||||||
| GtoPdb | - | - | 8.42 | pIC50 | 3.8 | nM | IC50 | J Med Chem (1996) 39: 625-56 [PMID:8576904] |
ChEMBL data shown on this page come from version 33:
Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]
