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ChEMBL ligand: CHEMBL1668599 (Citibrasine) |
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DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
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cathepsin V/Cathepsin L2 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3272] [GtoPdb: 2352] [UniProtKB: O60911] | ||||||||
ChEMBL | Inhibition of human recombinant cathepsin V expressed in Pichia pastoris by Lineweaver-Burk double-reciprocal plots | B | 6.7 | pKi | 200 | nM | Ki | Bioorg Med Chem (2011) 19: 1477-1481 [PMID:21277783] |
GtoPdb | - | - | 6.7 | pKi | 200 | nM | Ki | Bioorg Med Chem (2011) 19: 1477-81 [PMID:21277783] |
ChEMBL | Inhibition of human recombinant cathepsin V expressed in Pichia pastoris | B | 5.92 | pIC50 | 1200 | nM | IC50 | Bioorg Med Chem (2011) 19: 1477-1481 [PMID:21277783] |
ChEMBL data shown on this page come from version 32:
Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]