compound 4b [PMID: 20690647] [Ligand Id: 8614] activity data from GtoPdb and ChEMBL

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ChEMBL ligand: CHEMBL1240873
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  • calpain 1 in Pig [GtoPdb: 2336]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
Calpain 1 in Pig (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL4062] [UniProtKB: P35750]
ChEMBL Inhibition of porcine erythrocyte calpain 1 B 7.64 pKi 23 nM Ki J. Med. Chem. (2010) 53: 6326-6336 [PMID:20690647]
Calpain 2 in Pig (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL4143] [UniProtKB: P43367]
ChEMBL Inhibition of porcine kidney calpain 2 B 7.11 pKi 77 nM Ki J. Med. Chem. (2010) 53: 6326-6336 [PMID:20690647]
cathepsin B/Cathepsin B in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL4072] [GtoPdb: 2343] [UniProtKB: P07858]
ChEMBL Inhibition of human liver cathepsin B B 6.06 pKi 880 nM Ki J. Med. Chem. (2010) 53: 6326-6336 [PMID:20690647]
calpain 1 in Pig [GtoPdb: 2336]
GtoPdb - - 7.64 pKi 23 nM Ki J Med Chem (2010) 53: 6326-36 [PMID:20690647]

ChEMBL data shown on this page come from version 28:

Gaulton A, Hersey A, Nowotka M, Bento AP, Chambers J, Mendez D, Mutowo P, Atkinson F, Bellis LJ, CibriƔn-Uhalte E, Davies M, Dedman N, Karlsson A, MagariƱos MP, Overington JP, Papadatos G, Smit I, Leach AR. (2017) 'The ChEMBL database in 2017.' Nucleic Acids Res., 45(D1). DOI: 10.1093/nar/gkw1074. [PMCID:5210557]