compound 5 {PMID: 24900446] [Ligand Id: 8655] activity data from GtoPdb and ChEMBL
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| ChEMBL ligand: CHEMBL2047313 |
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| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
|---|---|---|---|---|---|---|---|---|
| kallikrein related peptidase 6/Kallikrein 6 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL4448] [GtoPdb: 2376] [UniProtKB: Q92876] | ||||||||
| GtoPdb | - | - | 5.82 | pIC50 | 1500 | nM | IC50 | ACS Med Chem Lett (2012) 3: 159-64 [PMID:24900446] |
| ChEMBL | Inhibition of N-terminus His6-tagged human kallikrein 6 expressed in baculovirus infected insect sf9 cells using Boc-Phe-Ser-Arg-AMC as substrate by fluorescence analysis | B | 5.82 | pIC50 | 1500 | nM | IC50 | ACS Med Chem Lett (2012) 3: 159-164 [PMID:24900446] |
ChEMBL data shown on this page come from version 33:
Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]
