compound 5 {PMID: 24900446] [Ligand Id: 8655] activity data from GtoPdb and ChEMBL

Click here for a description of the charts and data table

Please tell us if you are using this feature and what you think!

ChEMBL ligand: CHEMBL2047313
  • kallikrein related peptidase 6/Kallikrein 6 in Human [ChEMBL: CHEMBL4448] [GtoPdb: 2376] [UniProtKB: Q92876]
There should be some charts here, you may need to enable JavaScript!
DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
kallikrein related peptidase 6/Kallikrein 6 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL4448] [GtoPdb: 2376] [UniProtKB: Q92876]
GtoPdb - - 5.82 pIC50 1500 nM IC50 ACS Med Chem Lett (2012) 3: 159-64 [PMID:24900446]
ChEMBL Inhibition of N-terminus His6-tagged human kallikrein 6 expressed in baculovirus infected insect sf9 cells using Boc-Phe-Ser-Arg-AMC as substrate by fluorescence analysis B 5.82 pIC50 1500 nM IC50 ACS Med Chem Lett (2012) 3: 159-164 [PMID:24900446]

ChEMBL data shown on this page come from version 34:

Zdrazil B, Felix E, Hunter F, Manners EJ, Blackshaw J, Corbett S, de Veij M, Ioannidis H, Lopez DM, Mosquera JF, Magarinos MP, Bosc N, Arcila R, Kizilören T, Gaulton A, Bento AP, Adasme MF, Monecke P, Landrum GA, Leach AR. (2024). The ChEMBL Database in 2023: a drug discovery platform spanning multiple bioactivity data types and time periods. Nucleic Acids Res., 52(D1). DOI: 10.1093/nar/gkad1004. [EPMCID:10767899] [PMID:37933841]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]