GSK2033 [Ligand Id: 8690] activity data from GtoPdb and ChEMBL

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ChEMBL ligand: CHEMBL1093266 (GSK2033)
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  • Liver X receptor-α in Human [GtoPdb: 602] [UniProtKB: Q13133]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
Liver X receptor-β/LXR-beta in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL4093] [GtoPdb: 601] [UniProtKB: P55055]
GtoPdb - - 7.5 pIC50 - - - J Med Chem (2010) 53: 3412-6 [PMID:20345102]
ChEMBL Displacement of [N-methyl-3H]T1317 from human biotinylated LXRbeta LBD after 3 hrs by LEAD seeker binding assay B 7.5 pIC50 31.62 nM IC50 J. Med. Chem. (2010) 53: 3412-3416 [PMID:20345102]
Liver X receptor-α in Human [GtoPdb: 602] [UniProtKB: Q13133]
GtoPdb - - 7 pIC50 - - - J Med Chem (2010) 53: 3412-6 [PMID:20345102]

ChEMBL data shown on this page come from version 28:

Gaulton A, Hersey A, Nowotka M, Bento AP, Chambers J, Mendez D, Mutowo P, Atkinson F, Bellis LJ, CibriƔn-Uhalte E, Davies M, Dedman N, Karlsson A, MagariƱos MP, Overington JP, Papadatos G, Smit I, Leach AR. (2017) 'The ChEMBL database in 2017.' Nucleic Acids Res., 45(D1). DOI: 10.1093/nar/gkw1074. [PMCID:5210557]