ChEMBL ligand: CHEMBL205742
Monocarboxylate transporter 1 in Human [ChEMBL: CHEMBL4360] [GtoPdb: 988] [UniProtKB: P53985] There should be some charts here, you may need to enable JavaScript!

DB	Assay description	Assay Type	Standard value	Standard parameter	Original value	Original units	Original parameter	Reference
Monocarboxylate transporter 1 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL4360] [GtoPdb: 988] [UniProtKB: P53985]
ChEMBL	Displacement of [3H]5-[(3-hydroxypropyl)thio]-3-methyl-1-[2-(methyl-t)propyl-2,3-t2]-6-(1-naphthalenylmethyl)-1H-pyrrolo[3,4-d]pyrimidine-2,4(3H,6H)-dione from MCT1 in human Jurkat cell membranes	B	7.51	pKi	30.9	nM	Ki	Nat Chem Biol (2005) 1: 371-376 [PMID:16370372]
ChEMBL	Binding affinity to MCT1 by SPA	B	8.32	pKi	4.8	nM	Ki	Bioorg Med Chem Lett (2006) 16: 2260-2265 [PMID:16455256]
ChEMBL	Binding affinity to MCT1	B	8.32	pKi	4.8	nM	Ki	J Med Chem (2007) 50: 254-263 [PMID:17228867]
GtoPdb	-	-	8.32	pKi	4.8	nM	Ki	Bioorg Med Chem Lett (2006) 16: 2260-5 [PMID:16455256]
ChEMBL	Displacement of [3H]5-[(3-hydroxypropyl)thio]-3-methyl-1-[2-(methyl-t)propyl-2,3-t2]-6-(1-naphthalenylmethyl)-1H-pyrrolo[3,4-d]pyrimidine-2,4(3H,6H)-dione from human MCT1 expressed in INS1 cell membrane	B	8.48	pKi	3.31	nM	Ki	Nat Chem Biol (2005) 1: 371-376 [PMID:16370372]

ChEMBL data shown on this page come from version 33:

Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]