compound 4 [PMID: 16495056] [Ligand Id: 8832] activity data from GtoPdb and ChEMBL
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| ChEMBL ligand: CHEMBL208528 |
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| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
|---|---|---|---|---|---|---|---|---|
| CYP2J2/Cytochrome P450 2J2 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3491] [GtoPdb: 1332] [UniProtKB: P51589] | ||||||||
| ChEMBL | Inhibition of human recombinant CYP2J2 expressed in baculovirus-infected Sf9 insect cells | B | 6.8 | pKi | 160 | nM | Ki | Bioorg Med Chem Lett (2006) 16: 2777-2780 [PMID:16495056] |
| ChEMBL | Inhibition of human recombinant CYP2J2 expressed in baculovirus-infected Sf9 insect cells | B | 6.4 | pIC50 | 400 | nM | IC50 | Bioorg Med Chem Lett (2006) 16: 2777-2780 [PMID:16495056] |
| GtoPdb | Measuring CYP2J2-induced inhibition ebastine hydroxylation. | - | 6.8 | pIC50 | 160 | nM | IC50 | Bioorg Med Chem Lett (2006) 16: 2777-80 [PMID:16495056] |
ChEMBL data shown on this page come from version 33:
Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]
