S-4048 [Ligand Id: 8845] activity data from GtoPdb and ChEMBL

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ChEMBL ligand: CHEMBL236247
  • Glucose-6-phosphate transporter/Glucose-6-phosphate translocase in Human [ChEMBL: CHEMBL3217398] [GtoPdb: 1168] [UniProtKB: O43826]
  • Glucose-6-phosphate transporter in Rat [GtoPdb: 1168]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
Glucose-6-phosphate transporter/Glucose-6-phosphate translocase in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3217398] [GtoPdb: 1168] [UniProtKB: O43826]
ChEMBL Inhibition of glucose 6 phosphate translocase 1 B 8.52 pIC50 3 nM IC50 Bioorg. Med. Chem. (2007) 15: 5207-5218 [PMID:17524653]
ChEMBL Inhibition of G6PT1 (unknown origin) B 8.7 pIC50 2 nM IC50 MedChemComm (2012) 3: 926-931
Glucose-6-phosphate transporter in Rat [GtoPdb: 1168]
GtoPdb - - 8.7 pIC50 2 nM IC50 Medchemcomm (2012) 3: 926-931

ChEMBL data shown on this page come from version 27:

Gaulton A, Hersey A, Nowotka M, Bento AP, Chambers J, Mendez D, Mutowo P, Atkinson F, Bellis LJ, CibriƔn-Uhalte E, Davies M, Dedman N, Karlsson A, MagariƱos MP, Overington JP, Papadatos G, Smit I, Leach AR. (2017) 'The ChEMBL database in 2017.' Nucleic Acids Res., 45(D1). DOI: 10.1093/nar/gkw1074. [PMCID:5210557]