ChEMBL ligand: CHEMBL513136
δ receptor/Delta opioid receptor in Human [ChEMBL: CHEMBL236] [GtoPdb: 317] [UniProtKB: P41143] There should be some charts here, you may need to enable JavaScript!
κ receptor/Kappa opioid receptor in Human [ChEMBL: CHEMBL237] [GtoPdb: 318] [UniProtKB: P41145] There should be some charts here, you may need to enable JavaScript!
μ receptor/Mu opioid receptor in Human [ChEMBL: CHEMBL233] [GtoPdb: 319] [UniProtKB: P35372] There should be some charts here, you may need to enable JavaScript!
NOP receptor/Nociceptin receptor in Human [ChEMBL: CHEMBL2014] [GtoPdb: 320] [UniProtKB: P41146] NOP receptor in Mouse [GtoPdb: 320] [UniProtKB: P35377] NOP receptor in Rat [GtoPdb: 320] [UniProtKB: P35370] There should be some charts here, you may need to enable JavaScript!

DB	Assay description	Assay Type	Standard value	Standard parameter	Original value	Original units	Original parameter	Reference
δ receptor/Delta opioid receptor in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL236] [GtoPdb: 317] [UniProtKB: P41143]
GtoPdb	Radioligand binding assay	-	5.54	pKi	2854	nM	Ki	J Pharmacol Exp Ther (2008) 326: 672-82 [PMID:18492950]
ChEMBL	Displacement of [3H]diprenorphine from human delta opioid receptor expressed in CHO cells	B	5.54	pKi	2854	nM	Ki	Bioorg Med Chem Lett (2009) 19: 2519-2523 [PMID:19339177]
κ receptor/Kappa opioid receptor in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL237] [GtoPdb: 318] [UniProtKB: P41145]
GtoPdb	Radioligand binding assay	-	6.88	pKi	131	nM	Ki	J Pharmacol Exp Ther (2008) 326: 672-82 [PMID:18492950]
ChEMBL	Displacement of [3H]diprenorphine from human kappa opioid receptor expressed in CHO cells	B	6.88	pKi	131	nM	Ki	Bioorg Med Chem Lett (2009) 19: 2519-2523 [PMID:19339177]
μ receptor/Mu opioid receptor in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL233] [GtoPdb: 319] [UniProtKB: P35372]
ChEMBL	Displacement of [3H]diprenorphine from human mu opioid receptor expressed in CHO cells	B	7.19	pKi	65	nM	Ki	Bioorg Med Chem Lett (2009) 19: 2519-2523 [PMID:19339177]
GtoPdb	Radioligand binding assay	-	7.19	pKi	65	nM	Ki	J Pharmacol Exp Ther (2008) 326: 672-82 [PMID:18492950]
ChEMBL	Agonist activity at human mu opioid assessed as stimulation of GDP-induced [35S]GTPgammaS binding	F	6.16	pEC50	693	nM	EC50	Bioorg Med Chem Lett (2009) 19: 2519-2523 [PMID:19339177]
NOP receptor/Nociceptin receptor in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2014] [GtoPdb: 320] [UniProtKB: P41146]
GtoPdb	Radioligand binding assay	-	9.52	pKi	0.3	nM	Ki	J Pharmacol Exp Ther (2008) 326: 672-82 [PMID:18492950]
ChEMBL	Displacement of [125I][Tyr14]nociceptin from human cloned NOP receptor expressed in CHO cells	B	9.52	pKi	0.3	nM	Ki	Bioorg Med Chem Lett (2009) 19: 2519-2523 [PMID:19339177]
GtoPdb	Stimulation of GTP-γ35S binding	-	7.92	pEC50	12	nM	EC50	J Pharmacol Exp Ther (2008) 326: 672-82 [PMID:18492950]
ChEMBL	Agonist activity at human NOP assessed as stimulation of GDP-induced [35S]GTPgammaS binding	F	7.92	pEC50	12	nM	EC50	Bioorg Med Chem Lett (2009) 19: 2519-2523 [PMID:19339177]
NOP receptor in Mouse [GtoPdb: 320] [UniProtKB: P35377]
GtoPdb	Radioligand binding assay	-	8.94	pKi	1.15	nM	Ki	J Pharmacol Exp Ther (2008) 326: 672-82 [PMID:18492950]
NOP receptor in Rat [GtoPdb: 320] [UniProtKB: P35370]
GtoPdb	Radioligand binding assay	-	9.38	pKi	0.42	nM	Ki	J Pharmacol Exp Ther (2008) 326: 672-82 [PMID:18492950]

ChEMBL data shown on this page come from version 33:

Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]