quinostatin [Ligand Id: 8978] activity data from GtoPdb

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  • phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha in Human [GtoPdb: 2153] [UniProtKB: P42336]
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  • phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma in Human [GtoPdb: 2156] [UniProtKB: P48736]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha in Human [GtoPdb: 2153] [UniProtKB: P42336]
GtoPdb In vitro binding affinity to recombinant complex of PI3K alpha regulatory and catalytic subunits. - 6.22 pKd 600 nM Kd Chem. Biol. (2007) 14: 371-7 [PMID:17462572]
GtoPdb Inhibition of lipid-kinase activity in vitro. - 4.82 pIC50 15000 nM IC50 Chem. Biol. (2007) 14: 371-7 [PMID:17462572]
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma in Human [GtoPdb: 2156] [UniProtKB: P48736]
GtoPdb Inhibition of lipid-kinase activity in vitro. - 4.52 pIC50 30000 nM IC50 Chem. Biol. (2007) 14: 371-7 [PMID:17462572]

Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.